ChemicalBook > CAS DataBase List > 7-Chloro-1H-indole-3-carbaldehyde

7-Chloro-1H-indole-3-carbaldehyde

Product Name
7-Chloro-1H-indole-3-carbaldehyde
CAS No.
1008-07-7
Chemical Name
7-Chloro-1H-indole-3-carbaldehyde
Synonyms
7-CHLORO-3-FORMYLINDOLE;7-Chloro-3-formyl-1H-indole;7-Chloroindole-3-carbaldehyde;7-Chloro-3-indolecarboxaldehyde;7-Chloro-1H-indol-3-carbaldehyde;7-CHLORO-1H-INDOLE-3-CARBALDEHYDE;1H-Indole-3-carboxaldehyde, 7-chloro-;7-chloro-3-formylindole, CAS 1008-07-7
CBNumber
CB81519693
Molecular Formula
C9H6ClNO
Formula Weight
179.6
MOL File
1008-07-7.mol
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7-Chloro-1H-indole-3-carbaldehyde Property

Melting point:
181-182 °C(Solv: ethyl acetate (141-78-6))
Boiling point:
373.4±22.0 °C(Predicted)
Density 
1.431±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
13.92±0.30(Predicted)
Appearance
White to yellow Solid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B418635
Product name
7-Chloro-1H-indole-3-carbaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
0274AA
Product name
7-Chloro-1H-indole-3-carbaldehyde
Packaging
100mg
Price
$73
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC144366
Product name
7-Chloro-1H-indole-3-carbaldehyde
Packaging
500mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
024709
Product name
7-Chloroindole-3-carboxaldehyde
Purity
98%
Packaging
1g
Price
$92
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC144366
Product name
7-Chloro-1H-indole-3-carbaldehyde
Packaging
1g
Price
$120
Updated
2021/12/16
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7-Chloro-1H-indole-3-carbaldehyde Chemical Properties,Usage,Production

Synthesis

53924-05-3

1008-07-7

The general procedure for the synthesis of 7-chloro-1H-indole-3-aldehyde from 7-chloro-1H-indole was as follows: phosphoryl chloride (0.66 mL, 7 mmol) was slowly added dropwise to anhydrous DMF (5 mL) at 0 °C and under argon protection. Subsequently, a solution of 7-chloro-1H-indole (1 g, 6.6 mmol) dissolved in anhydrous DMF (15 mL) was added dropwise to the above mixture at room temperature. The reaction mixture was stirred continuously for 2 hours at room temperature. After completion of the reaction, the mixture was slowly poured into a mixture of ice water and saturated NaHCO3 solution and extracted with ethyl acetate. The organic phases were combined, washed with saturated NaCl solution (10 mL x 3), dried over anhydrous MgSO4, filtered and concentrated to give 990 mg of the target product 7-chloro-1H-indole-3-aldehyde as a yellow-orange solid in 83% yield.

References

[1] Patent: US2005/119260, 2005, A1. Location in patent: Page/Page column 36

7-Chloro-1H-indole-3-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7-Chloro-1H-indole-3-carbaldehyde manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
7-Chloro-1H-indole-3-carbaldehyde 1008-07-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-19
Shaanxi Dideu Medichem Co. Ltd
Product
7-CHLORO-3-FORMYLINDOLE 1008-07-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2024-07-30
Zhuozhou Wenxi import and Export Co., Ltd
Product
7-chloro-3-forMylindole 1008-07-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

1008-07-7, 7-Chloro-1H-indole-3-carbaldehydeRelated Search:

7-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID 3-HYDROXY-7-CHLORO 1H-INDAZOLE METHYL 7-CHLORO-1H-INDAZOLE-3-CARBOXYLATE 7-Chloroindole 7-CHLORO-1H-INDAZOL-3-YLAMINE 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE 7-Chloro-3H-[1,2,3]triazolo[4,5-b]pyridine 7-chloro-1H-pyrrolo[3,2-b]pyridin-3-aMine 7-Chloro-1H-imidazo[4,5-c]pyridine 7-CHLORO-1H-INDOL-3-METHYLAMINE 7-CHLORO-1H-INDOLE-3-CARBOXYLIC ACID 1H-Indole-3-carboxylic acid, 2-aminomethyl-1-ethyl-4,5,6,7-tetrachloro -, ethyl ester 7-CHLORO-ALPHA-OXO-1H-INDOLE-3-ACETYL CHLORIDE 8-chloro-2,2-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-4-one 7-CHLORO-3-FORMYLINDOLE

  • 7-CHLORO-3-FORMYLINDOLE
  • 7-Chloro-3-indolecarboxaldehyde
  • 1H-Indole-3-carboxaldehyde, 7-chloro-
  • 7-Chloro-3-formyl-1H-indole
  • 7-Chloroindole-3-carbaldehyde
  • 7-CHLORO-1H-INDOLE-3-CARBALDEHYDE
  • 7-chloro-3-formylindole, CAS 1008-07-7
  • 7-Chloro-1H-indol-3-carbaldehyde
  • 1008-07-7