2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE

Product Name: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE
CAS No.: 945-43-7
Chemical Name: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE
Synonyms: DMPH4;6,7-DIMETHYL-5,6,7,8-TETRAHYDRO-PTERINE MONOHYDROC;6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIN HYDROCHLORIDE;6,7-dimethyl-5,6,7,8-tetrahydropterin dihydrochloride;6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERINE MONOHYDROCHLORIDE;2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE;2-amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine;6,7-DiMethyl-5,6,7,8-tetrahydropterine hydrochloride >=95%;2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridineHCl;2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride
CBNumber: CB8160795
Molecular Formula: C8H14ClN5O
Formula Weight: 231.68
MOL File: 945-43-7.mol

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2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE Property

Melting point:: 244-247 °C (dec.)(lit.)
storage temp.: -20°C
solubility: PBS (pH 7.2): 1 mg/ml
form: White powder.

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-41-37/38
Safety Statements: 26-36-36/37/39-39
WGK Germany: -

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D0387
Product name: 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride
Purity: ≥95%
Packaging: 100mg
Price: $132
Updated: 2025/07/31

Cayman Chemical

Product number: 21050
Product name: 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $18
Updated: 2024/03/01

Cayman Chemical

Product number: 21050
Product name: 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride)
Purity: ≥98%
Packaging: 50mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 21050
Product name: 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride)
Purity: ≥98%
Packaging: 100mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 21050
Product name: 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride)
Purity: ≥98%
Packaging: 250mg
Price: $144
Updated: 2024/03/01

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2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes[1][2].

Biochem/physiol Actions

Synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4).

References

[1] Mayer B, et al. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351(5):453-63. DOI:10.1007/BF00171035
[2] Suckling CJ, et al. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1563-6. DOI:10.1016/j.bmcl.2008.01.079

2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

2,3-Butanedione Sodium sulfite Hydrochloric acid Sodium hydroxide 2,5,6-Triaminopyrimidin-4-ol sulphate Carbon Sodium carbonate

Preparation Products

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2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE Suppliers

China 29 Germany 1 Switzerland 2 United Kingdom 1 United States 8 Global 41

Shandong Xiya Chemical Co., Ltd

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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CONIER CHEM AND PHARMA LIMITED

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945-43-7, 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDERelated Search:

2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE Cyclohexane Dimethanol Dimethylacrylate Allyl methyl carbonate 2-Hydroxyethyl methacrylate

2-amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine

6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERINE MONOHYDROCHLORIDE

6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIN HYDROCHLORIDE

2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE

2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE

2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE

2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE

2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride

6,7-DIMETHYL-5,6,7,8-TETRAHYDRO-PTERINE MONOHYDROC

2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridineHCl

6,7-dimethyl-5,6,7,8-tetrahydropterin dihydrochloride

2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4

2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4, 2-Amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinol hydrochloride

2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridine-4-ol·hydrochloride

2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine hydrochloride,96%

DMPH4

6,7-DiMethyl-5,6,7,8-tetrahydropterine hydrochloride >=95%

2-Amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinol hydrochloride

2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one hydrochloride

945-43-7

C8H14ClN5O

C8H13N5O2ClH

C8H13N5OHCl

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Quinazolines

Heterocyclic Building Blocks

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Chemical Synthesis

Heterocyclic Building Blocks

Quinazolines