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Tris(hydroxymethyl)nitromethane

Product Name
Tris(hydroxymethyl)nitromethane
CAS No.
126-11-4
Chemical Name
Tris(hydroxymethyl)nitromethane
Synonyms
2-(Hydroxymethyl)-2-nitropropane-1,3-diol;Nitroisobutylglycerol;2-(HYDROXYMETHYL)-2-NITRO-1,3-PROPANEDIOL;AKOS 374;trisnitro;Tris Nitro;cimcoolwafers;Cimcool wafers;Trishydroxymethyl;SPECTRIS(TM) NITRO
CBNumber
CB8163079
Molecular Formula
C4H9NO5
Formula Weight
151.12
MOL File
126-11-4.mol
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Tris(hydroxymethyl)nitromethane Property

Melting point:
160 °C (dec.) (lit.)
Boiling point:
273.1°C (rough estimate)
Density 
1.5652 (rough estimate)
refractive index 
1.4183 (estimate)
storage temp. 
Store at room temperature
solubility 
H2O: soluble220g/100ml at 20°C
pka
12.32±0.10(Predicted)
form 
powder to lump
color 
White to Almost white
Water Solubility 
It is soluble in water.
Merck 
14,9753
BRN 
742427
LogP
0.350 (est)
CAS DataBase Reference
126-11-4(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-(126-11-4)
EPA Substance Registry System
2-(Hydroxymethyl)-2-nitro-1,3-propanediol (126-11-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
26-36
WGK Germany 
3
RTECS 
TY7350000
F 
4.10
TSCA 
Yes
HS Code 
29221990
Hazardous Substances Data
126-11-4(Hazardous Substances Data)
Toxicity
mouse,LD50,intraperitoneal,4gm/kg (4000mg/kg),Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 11(1), Pg. 73, 1977.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108189
Product name
Tris(hydroxymethyl)nitromethane
Purity
98%
Packaging
100g
Price
$68.59
Updated
2025/07/31
Sigma-Aldrich
Product number
108189
Product name
Tris(hydroxymethyl)nitromethane
Purity
98%
Packaging
500g
Price
$270.75
Updated
2025/07/31
TCI Chemical
Product number
H0271
Product name
2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Purity
>99.0%(GC)
Packaging
25g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
H0271
Product name
2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Purity
>99.0%(GC)
Packaging
500g
Price
$163
Updated
2025/07/31
TRC
Product number
T884953
Product name
Tris(hydroxymethyl)nitromethane
Packaging
1g
Price
$45
Updated
2021/12/16
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Tris(hydroxymethyl)nitromethane Chemical Properties,Usage,Production

Chemical Properties

Off-white to orange solid. It crystallizes as white crystals in the mixed solution of ethyl acetate and benzene. Soluble in alcohol, slightly soluble in benzene and other hydrocarbons. Solubility in water (20°C) 220g/100ml.

Uses

Tris(hydroxymethyl)nitromethane, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is used as a primary and secondary intermediate.

Preparation

Tris(hydroxymethyl)nitromethane is prepared by the condensation of nitromethane and formaldehyde under basic conditions.

Application

Tris(hydroxymethyl)nitromethane is a bactericide and slimicide for use in cooling fluids, paper and pulp industry; as a curing agent for certain adhesives; viscositycontrolling agent in cosmetics.To inhibit bacterial growth in circulating industrial water systems, cutting oils, nonprotein glues and sizings.

General Description

Tris(hydroxymethyl)nitromethane undergoes crosslinking with hexamethylene diisocyanate to form monolithic energetic gels. It is an effective hardener for variety of tannin-based adhesives.

Hazard

Moderate fire risk. Irritant to skin and eyes.

Purification Methods

Crystallise it from CHCl3/ethyl acetate or ethyl acetate/*benzene. It is an acid and a 0.1M solution in H2O has pH 4.5. IRRITANT. [Beilstein 1 H 520.]

Tris(hydroxymethyl)nitromethane Preparation Products And Raw materials

Raw materials

Nitromethane

Preparation Products

Tris(hydroxymethyl)aminomethane
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Tris(hydroxymethyl)nitromethane Suppliers

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View Lastest Price from Tris(hydroxymethyl)nitromethane manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Tris(hydroxymethyl)nitromethane 126-11-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-11-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tris(hydroxymethyl)nitromethane 126-11-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-08-19
Hebei Chuanghai Biotechnology Co., Ltd
Product
Tris(hydroxymethyl)nitromethane 126-11-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-11-11

126-11-4, Tris(hydroxymethyl)nitromethaneRelated Search:

BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE) 2-Hydroxyethyl methacrylate BIS-Tris Trimethylolpropane CARBOXYMETHYLCELLULOSE SODIUM SALT 1,3-Propanediol Tricine 2-Methyl-2-nitropropane 2-Nitroethanol 2-METHYL-1,3-PROPANEDIOL 1,1,1-Tris(hydroxymethyl)ethane Tris(dibenzylideneacetone)dipalladium-chloroform adduct Tris(dibenzylideneacetone)dipalladium TRIS(HYDROXYPROPYL)PHOSPHINE Tris(dimethylaminomethyl)phenol Tris(hydroxymethyl)aminomethane Tris(triphenylphosphine)chlororhodium Trisodium methanetrisulfonate

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