4-Azabenzimidazole
- Product Name
- 4-Azabenzimidazole
- CAS No.
- 273-21-2
- Chemical Name
- 4-Azabenzimidazole
- Synonyms
- 4H-Imidazo[4,5-b]pyridine;PBTFL44;1-deazapurine;3,4-diazaindole;4-AZABENZIMIDAZOLE;7-azabenzimidazole;TIMTEC-BB SBB004292;Imidazo(4,5-b)pyridine;4-AZABENZIMIDAZOLE 99%;pyrido(2,3-d)imidazole
- CBNumber
- CB8165215
- Molecular Formula
- C6H5N3
- Formula Weight
- 119.12
- MOL File
- 273-21-2.mol
4-Azabenzimidazole Property
- Melting point:
- 148-151 °C (lit.)
- Boiling point:
- 140-150°C/0.1mm
- Density
- 1.2058 (rough estimate)
- refractive index
- 1.5589 (estimate)
- Flash point:
- 140-150°C/0.1mm
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in dimethylformamide.
- form
- powder
- pka
- 8.46±0.20(Predicted)
- Appearance
- Off-white to light brown Solid
- BRN
- 2600
- CAS DataBase Reference
- 273-21-2(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Imidazo[4,5-b]pyridine (273-21-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A93607
- Product name
- 4-Azabenzimidazole
- Purity
- 99%
- Packaging
- 1g
- Price
- $92.2
- Updated
- 2025/07/31
- Product number
- A93607
- Product name
- 4-Azabenzimidazole
- Purity
- 99%
- Packaging
- 5g
- Price
- $347
- Updated
- 2023/06/20
- Product number
- A795195
- Product name
- 4-Azabenzimidazole
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- CHM0025447
- Product name
- 4-AZABENZIMIDAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $169.05
- Updated
- 2021/12/16
- Product number
- CHM0025447
- Product name
- 4-AZABENZIMIDAZOLE
- Purity
- 95.00%
- Packaging
- 20G
- Price
- $1218.4
- Updated
- 2021/12/16
4-Azabenzimidazole Chemical Properties,Usage,Production
Chemical Properties
yellow to light brown powder
Uses
4-Azabenzimidazole is used in the preparation of imidazo[4,5-b]pyridine 4-oxide. It is also used as a reagent to prepare benzoylmethyl-substituted azoles which are inhibitors of nitric oxide synthase with antioxidant properties.
Definition
ChEBI: The [4,5-b]-fused isomer of imidazopyridine.
Synthesis
452-58-4
122-51-0
273-21-2
The general procedure for the synthesis of 4-azabenzimidazole from 2,3-diaminopyridine and triethyl orthoformate was as follows: to evaluate the catalytic performance of different γ-Fe2O3@SiO2-HA catalysts, a catalytic amount of γ-Fe2O3@SiO2-HA (2.5 mol%) was added to a glass flask containing 1.2 mmol of triethyl orthoformate and stirred at room temperature for 15 minutes. Subsequently, 2 mmol of 2,3-diaminopyridine was added to the reaction mixture and the reaction was continued until a predetermined time was reached. The progress of the reaction was monitored by thin layer chromatography (TLC) and the unfolding agent was a solvent mixture of hexane and ethyl acetate (ratio 4:1 or 7:3 for diamines). Upon completion of the reaction, 5 mL of dichloromethane (ethyl acetate was used for entries 8 and 9) was added to the mixture, followed by separation of the catalyst by an external magnet for subsequent use. Finally, the resulting solution was concentrated on a rotary evaporator to give the purified 4-azabenzimidazole solid product.
References
[1] Asian Journal of Chemistry, 2013, vol. 25, # 6, p. 3446 - 3448
[2] Journal of Molecular Structure, 2012, vol. 1027, p. 156 - 161
4-Azabenzimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Azabenzimidazole manufacturers
- Product
- 4-Azabenzimidazole 273-21-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- 4-Azabenzimidazole 273-21-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-02