ChemicalBook > CAS DataBase List > CATHEPSIN L

CATHEPSIN L

Product Name
CATHEPSIN L
Chemical Name
CATHEPSIN L
Synonyms
CATHEPSIN L;EC 3.4.22.15;Caspases 3&7;Magic Red™HUMAN CATHEPSIN-L;CATHEPSIN L (HUMAN);CATHEPSIN L, HUMAN LIVER
CBNumber
CB8167880
Formula Weight
0
MOL File
Mol file
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CATHEPSIN L Property

storage temp. 
−20°C
form 
solution
biological source
human liver
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Safety

Hazard Codes 
B
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
219402
Product name
Cathepsin L, Human Liver
Packaging
25μg
Price
$456
Updated
2025/07/31
Usbiological
Product number
144288
Product name
Cathepsin L
Packaging
100ug
Price
$490
Updated
2021/12/16
Usbiological
Product number
C2097-70
Product name
Cathepsin L
Packaging
1ml
Price
$596
Updated
2021/12/16
Usbiological
Product number
024015
Product name
Cathepsin L
Packaging
96Tests
Price
$809
Updated
2021/12/16
Usbiological
Product number
153936
Product name
Cathepsin L
Packaging
10ug
Price
$350
Updated
2021/12/16
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CATHEPSIN L Chemical Properties,Usage,Production

Uses

life science and biopharma

Biological Activity

Cathepsin L (CTSL) has higher activity than cathepsins B and H in the degradation of a variety of physiological protein substrates. It is believed to be responsible for the generation of endostatin from the NC1 domain in collagen XVII. It is responsible for regulating cell cycle, nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3 (NLRP3) inflammasome activation, proteolytic processing of Bid during apoptosis, and TGF-β signaling. It can degrade a wide range of proteins, encompassing enzymes, receptors, and transcription factors. Additionally, it produces active enzymes, receptors, and biologically active peptides through controlled proteolysis. Moreover, Cathepsin L has been observed to enhance tumor cell migration by lowering cell-cell adhesion and breaking down elements of the extracellular matrix. The expression of CTSL escalates in several types of cancers, including glioma, melanoma, pancreatic, prostate, and breast cancer. It plays a major role in the proteolysis of both cellular and endocytosed macromolecules.

CATHEPSIN L Preparation Products And Raw materials

Raw materials

Preparation Products

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CATHEPSIN L Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai Huzhen Industrial Co., LTD
Tel
021-60345367 13916550749
Email
sales@shzbio.com
Country
China
ProdList
9965
Advantage
58
ACROBiosystems
Tel
13121935750
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
1354
Advantage
58
ZSGB-BIO
Tel
02-400-810-9781 400810978
Email
sales@zsbio.com
Country
China
ProdList
2887
Advantage
58
Merck Millipore
Tel
1-400-889-1988 400-889-1988
Email
bioscience@merckgroup.com
Country
China
ProdList
6839
Advantage
58
Bio Rad Laboratories Inc
Tel
65-64153170
Email
Sales.China@bio-rad.com
Country
China
ProdList
6054
Advantage
58
BioVendor R D
Tel
420-549124185
Email
info@biovendor.com
Country
China
ProdList
1266
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58
Beijing Biosynthesis Biotechnology Co Ltd
Tel
400-9019800
Email
sales@bioss.com.cn
Country
China
ProdList
6102
Advantage
58
Rockland Immunochemicals Inc
Tel
0512-65829739
Email
antibodies-onlinename@qq.com
Country
China
ProdList
0
Advantage
58

CATHEPSIN LRelated Search:


  • HUMAN CATHEPSIN-L
  • EC 3.4.22.15
  • CATHEPSIN L
  • CATHEPSIN L (HUMAN)
  • CATHEPSIN L, HUMAN LIVER
  • Magic Red&#8482
  • Caspases 3&7
  • BioChemical
  • Cathepsins and Granzymes
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Apoptosis and Cell Cycle
  • Enzymes