ChemicalBook > CAS DataBase List > INDO 1-AM

INDO 1-AM

Product Name
INDO 1-AM
CAS No.
112926-02-0
Chemical Name
INDO 1-AM
Synonyms
INDO 1-AM;Indo-1-ame;Indo 1 Am Ester;INDO 1-AM SOLUTION;Indo-1, AM *SP-Pak*;INDO 1-AM, FOR FLUORESCENCE;INDO 1/AM (1SET = 10x100UG);Indo-1, AM *CAS 112926-02-0*;Indo-1, AM *UltraPure Grade*;indo-1pentaacetoxymethylester
CBNumber
CB8176659
Molecular Formula
C47H51N3O22
Formula Weight
1009.91
MOL File
112926-02-0.mol
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INDO 1-AM Property

Melting point:
>250 ℃
Boiling point:
1009.2±65.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble
form 
powder
pka
14.85±0.30(Predicted)
color 
Light yellow
Appearance
Solid Powder
λmax
356nm
Biological Applications
Calcium indicator; preventing arrhythmias
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
8-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20417
Product name
Indo-1 AM
Purity
≥90%
Packaging
1mg
Price
$110
Updated
2024/03/01
Tocris
Product number
6704
Product name
Indo 1-AM
Purity
≥90%(HPLC)
Packaging
1
Price
$195
Updated
2021/12/16
TRC
Product number
I655605
Product name
Indo 1-AM
Packaging
2.5mg
Price
$370
Updated
2021/12/16
TRC
Product number
I655605
Product name
Indo 1-AM
Packaging
10mg
Price
$1340
Updated
2021/12/16
AK Scientific
Product number
8853CA
Product name
Indo-1pentaacetoxymethylester
Packaging
1mg
Price
$220
Updated
2021/12/16
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INDO 1-AM Chemical Properties,Usage,Production

Description

Indo-1 AM is a cell-permeant acetoxymethyl ester of indo-1, a ratiometric fluorescent calcium indicator. Indo-1 AM is hydrolyzed by intracellular esterases to release Indo-1 in cells. Indo-1 is commonly used in flow cytometry. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when indo-1 binds calcium.

Chemical Properties

yellow solid

Uses

INDO 1/AM is a cell permeable derivative of INDO 1.

Uses

Cell permeable fluorescent probe for Ca2+; lower affinity than FURA?2; gives a large shift in fluorescent emission from 482?nm to 398?nm upon Ca2+ binding.

Uses

Cell-permeant derivative of Indo 1. Indo 1-AM is fluorescent probe for Ca2+. After crossing the membrane, the product is rapidly hydrolyzed by cytoplasmic esterases to the membrane impermeant INDO 1. Indo 1-AM is possible using for ratiometric fluorescenc

storage

-20°C

Excitation / Emission Maximum

349-364 nm/475-485 nm (no Ca2+), 400-410 nm (Ca2+-bound)

INDO 1-AM Preparation Products And Raw materials

Raw materials

Preparation Products

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INDO 1-AM Suppliers

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112926-02-0, INDO 1-AMRelated Search:

Methyl indole-6-carboxylate 2-Phenylindole Ethylene glycol diphenyl ether Iminodiacetic acid 1,2-Bis(3-methylphenoxy)ethane METHYLENE DIACETATE, 99 6-Methylindole Indole-6-carboxaldehyde N-PHENYLIMINODIACETIC ACID BAPTA 2,2'-(P-TOLYLIMINO)DIETHANOL N-Methyliminodiacetic acid 4-(1H-INDOL-2-YL)-PHENYLAMINE Indole-6-carboxylic acid 2-(2-phenoxyethoxy)phenylamine P-TOLYLAMINO-ACETIC ACID N-Methyl-bis(2-methoxyethyl)amine 1H-INDOLE, 2-(3-METHOXYPHENYL)-

  • indo-1pentaacetoxymethylester
  • 1-[2-AMINO-5-(6-CARBOXYINDOL-2-YL)PHENOXY]-2-(2'-AMINO-5'-METHYLPHENOXY) ETHANE-N,N,N',N'-TETRAACETIC ACID PENTAACETOXYMETHYL ESTER
  • 1-[2-AMINO-5-(6-CARBOXYINDOL-2-YL)PHENOXY]-2-(2'-AMINO-5'-METHYLPHENOXY) ETHANE-N,N,N,N-TETRAACETIC ACID PENTAACETOXY-METHYL ESTER
  • 4-(6-CARBOXY-2-INDOLYL)-4'-METHYL-2,2'-(ETHYLENEDIOXY)DIANILINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL) ESTER
  • ACETOXYMETHYL ESTER OF INDO 1
  • INDO 1/AM (1SET = 10x100UG)
  • INDO 1-AM >93% FLUORESCENT MARKER FO
  • INDO 1-AM, FOR FLUORESCENCE
  • 4-(6-Carboxy-2-indolyl)-4'-methyl-2,2'-(ethylenedioxy)dianiline-
  • Indo-1-ame
  • 1-[2-Amino-5-(6-carboxy-2-indolyl)phenoxy]-2-(2-amino-5-methylphenoxy)ethane-N,N,N',N'-tetraaceticacid,pentaacetoxymethylester
  • INDO 1-AM SOLUTION
  • INDO 1-AM
  • 2-[4-[Bis[2-[(acetoxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (acetoxy)methyl ester
  • 2-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoetyl]amino]-5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (acetyloxy)methyl ester
  • Indo-1, AM *SP-Pak*
  • Ind)-3-(p-nitrophenyl)-5-phenyltetrazolium Chloride
  • 3(p-nitrophenyl)-2-(p-iodophenyl)-5-phenyltetrazolium Chloride
  • P-iodonitrotetrazolium Violet O 1 Acetoxymethyl Ester
  • Indo 1 Am Ester
  • Indo-1, AM *CAS 112926-02-0*
  • Indo-1, AM *UltraPure Grade* *CAS 112926-02-0*
  • 1H-Indole-6-carboxylic acid, 2-[4-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-, (acetyloxy)methyl ester
  • Indo-1 AM ,(Synonyms: Indo-1 Acetoxymethyl ester)
  • Indo-1 AM, fluorescent Ca2+ indicator
  • Indo-1, AM *UltraPure Grade*
  • 112926-02-0
  • C47H51N3O22
  • Fluorescent Probes, Labels, Particles and Stains
  • Detection
  • BioChemical
  • Biochemicals and Reagents
  • Indole