ChemicalBook > CAS DataBase List > trans-Zeatin

trans-Zeatin

Product Name
trans-Zeatin
CAS No.
1637-39-4
Chemical Name
trans-Zeatin
Synonyms
Zeatine;(E)-Zeatin;rans-zeatin;TRANS-ZEATIN;Zeatin (7CI);(e)-2-buten-1-o;trans-ZEATIN (Z);Trans-Zeatin HCl;TRANS ISOMER-ZEATIN;ZEATIN TRANS ISOMER
CBNumber
CB8177373
Molecular Formula
C10H13N5O
Formula Weight
219.24
MOL File
1637-39-4.mol
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trans-Zeatin Property

Melting point:
207 °C
Boiling point:
395.0±52.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: soluble
form 
powder
pka
14.77±0.10(Predicted)
color 
off-white to yellow
Merck 
14,10117
BRN 
616241
InChI
InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
InChIKey
UZKQTCBAMSWPJD-FARCUNLSSA-N
SMILES
C(O)/C(/C)=C/CNC1=C2C(=NC=N1)NC=N2
CAS DataBase Reference
1637-39-4(CAS DataBase Reference)
EPA Substance Registry System
Zeatin (1637-39-4)
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Safety

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
EM9506000
8-10-23
HS Code 
29335990
Hazardous Substances Data
1637-39-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Z0876
Product name
trans-Zeatin
Purity
BioReagent, plant cell culture tested, ≥97%
Packaging
5mg
Price
$67.9
Updated
2024/03/01
Sigma-Aldrich
Product number
Z0876
Product name
trans-Zeatin
Purity
BioReagent, plant cell culture tested, ≥97%
Packaging
10mg
Price
$118
Updated
2024/03/01
TCI Chemical
Product number
Z0012
Product name
trans-Zeatin
Purity
>98.0%(HPLC)(N)
Packaging
100mg
Price
$297
Updated
2024/03/01
Alfa Aesar
Product number
J61972
Product name
trans-Zeatin, 97%
Packaging
50mg
Price
$252.65
Updated
2024/03/01
Alfa Aesar
Product number
J61972
Product name
trans-Zeatin, 97%
Packaging
100mg
Price
$437
Updated
2024/03/01
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trans-Zeatin Chemical Properties,Usage,Production

Description

trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities. It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM. trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner. It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 μM. trans-Zeatin (25-100 μM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells. It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.

Chemical Properties

white to light yellow crystal powder

Physical properties

Trans-zeatin is freely soluble in acetic acid and water.

Uses

Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form. Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging.

Definition

Increased levels of cytokinins such as trans-zeatin, which are considered highly active, induced resistance against mainly (hemi)biotrophic pathogens in different plant species. In contrast, cis-zeatin is commonly regarded as a cytokinin exhibiting low or no activity [1].

Definition

ChEBI: The trans-isomer of zeatin.

General Description

trans-Zeatin contains a hydroxylated isoprenoid side chain.

Biochem/physiol Actions

Zeatin upon reduction forms zeatin O-glucoside, which is widely present in plants. It possesses transportation and storage functions, along with defence against zeatin oxidases.

Purification Methods

Purify zeatin by recrystallisation from EtOH or H2O. The UV has max at 207 and 275nm ( 1,400 and 14,650) in 0.1N aqueous HCl; 212 and 270nm ( 17,050 and 16,150) in aqueous buffer pH 7.2; 220 and 276nm ( 15,900 and 14,650) in 0.1N aqueous NaOH. The picrate has m 192-194o (from H2O) from which zeatin can be recovered by treatment with Dowex-1 x 8 (200-400 mesh, OH-form). [Letham et al. Aust J Chem 22 205 1969, Proc Chem Soc (London) 230 1964, Shaw & Wilson Proc Chem Soc (London) 231 1964.] It is a cell division factor (plant growth regulator) [Letham & Palni Ann Rev Plant Physiol 34 163 1983] and inhibits mitochondrial function [Miller Plant Physiol 69 1274 1982]. The commercially available trans -9-riboside derivative, [6025-53-2], M 351.4,is a cytokine which separates from aqueous AcOH with m 177-179o. It solubility in AcOH is ~5%. [McDonald & Morris Methods Enzymol 100 347 1985].

References

[1] Dominik K Gro?kinsky. “Cis- and trans-zeatin differentially modulate plant immunity.” Plant Signaling Behavior 8 7 (2013): e24798.

trans-Zeatin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from trans-Zeatin manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
trans-Zeatin 1637-39-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
trans-Zeatin 1637-39-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
1000kg/month
Release date
2023-01-04
Hebei Weibang Biotechnology Co., Ltd
Product
trans-Zeatin 1637-39-4
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-07-30

1637-39-4, trans-ZeatinRelated Search:


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