ChemicalBook > CAS DataBase List > (R)-2-HYDROXY-4-METHYLPENTANOIC ACID

(R)-2-HYDROXY-4-METHYLPENTANOIC ACID

Product Name
(R)-2-HYDROXY-4-METHYLPENTANOIC ACID
CAS No.
20312-37-2
Chemical Name
(R)-2-HYDROXY-4-METHYLPENTANOIC ACID
Synonyms
D-Leucic acid;(2R)-2-hydroxy-4-methylpentanoic acid;(R)-Leucic acid;2-hydroxy-4-Methyl-;(-)-??-hydroxyisocaproate;D-a-Hydroxyisocaproic acid;D-2-Hydroxyisocaproic acid;D-α-Hydroxyisocaproic acid;D-ALPHA-HYDROXYISOCAPROIC ACID;R-2-Hydroxy-4-methylvaleric acid
CBNumber
CB8178880
Molecular Formula
C6H12O3
Formula Weight
132.16
MOL File
20312-37-2.mol
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(R)-2-HYDROXY-4-METHYLPENTANOIC ACID Property

Melting point:
76-80℃
Boiling point:
251.3±13.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
pka
3.86±0.21(Predicted)
form 
Solid
color 
White to off-white
LogP
0.522 (est)
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Safety

HS Code 
2918199890
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
H972440
Product name
(R)-2-Hydroxy-4-methylpentanoicacid
Packaging
100mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
279949
Product name
D-alpha-Hydroxyisocaproic acid
Packaging
500mg
Price
$333
Updated
2021/12/16
ChemScene
Product number
CS-0000170
Product name
(R)-Leucicacid
Purity
≥97.0%
Packaging
10g
Price
$345
Updated
2021/12/16
Apolloscientific
Product number
OR964438
Product name
(R)-2-Hydroxy-4-methylpentanoicacid
Purity
97%
Packaging
5g
Price
$443
Updated
2021/12/16
AK Scientific
Product number
V4198
Product name
(R)-2-Hydroxy-4-methylpentanoicacid
Packaging
5g
Price
$455
Updated
2021/12/16
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(R)-2-HYDROXY-4-METHYLPENTANOIC ACID Chemical Properties,Usage,Production

Uses

(R)-Leucic acid is an amino acid metabolite[1].

Definition

ChEBI: The (R)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Found in patients with short-bowel syndrome (an inborn error of metabolism), and in maple syrup urine disease, MSUD.

References

[1] Buck, S. B., et al. Total Synthesis and Anti-Tubulin Activity of Epi-C3 Analogues of Cryptophycin-24. Journal of Medicinal Chemistry, 2004. 47(14), 3697–3699.

(R)-2-HYDROXY-4-METHYLPENTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-HYDROXY-4-METHYLPENTANOIC ACID Suppliers

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20312-37-2, (R)-2-HYDROXY-4-METHYLPENTANOIC ACIDRelated Search:

MONOCROTALINE AZADIRACHTIN H(SH) PICROTOXININ Bilobalide PICROTOXIN Vincristine sulfate Azadirachtin (2S,3S)-(2S,3R)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID (2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid 2-hydroxy-4-methylpentanoic acid L-LEUCIC ACID (2R,3S)-(-)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID, 99+% E.E., 99.5+%,(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid (R)-2-HYDROXY-4-METHYLPENTANOIC ACID (1R)-(+)-CAMPHANIC ACID bruceine D bruceine E BOC-(2R,3S)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID FMOC-(2S,3R)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID

  • D-ALPHA-HYDROXYISOCAPROIC ACID
  • (R)-2-HYDROXY-4-METHYLPENTANOIC ACID
  • (2R)-2-hydroxy-4-methylpentanoic acid
  • D-Leucic acid
  • D-2-Hydroxy-4-methylpentanoic acid
  • D-a-Hydroxyisocaproic acid
  • (R)-Leucic acid
  • (2R)-2-hydroxy-4-methyl-valeric acid
  • 2-hydroxy-4-Methyl-
  • D-2-Hydroxyisocaproic acid
  • R-2-Hydroxy-4-methylvaleric acid
  • Pentanoic acid, 2-hydroxy-4-methyl-, (2R)-
  • D-α-Hydroxyisocaproic acid
  • (R)-2-hydroxy-4-methylpentanoicaci
  • (-)-??-hydroxyisocaproate
  • 20312-37-2
  • API intermediates
  • pharmacetical