1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol
- Product Name
- 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol
- CAS No.
- 685514-01-6
- Chemical Name
- 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol
- Synonyms
- 1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol;1-triisopropylsilylpyrrolo[2,3-b]pyridin-5-ol;1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-ol;1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[Tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-;1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-sulfonic acid
- CBNumber
- CB81871753
- Molecular Formula
- C16H26N2OSi
- Formula Weight
- 290.48
- MOL File
- 685514-01-6.mol
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Property
- Boiling point:
- 341.6±35.0 °C(Predicted)
- Density
- 1.03±0.1 g/cm3(Predicted)
- pka
- 8.50±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-B1523
- Product name
- 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- CS-B1523
- Product name
- 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
- Packaging
- 1g
- Price
- $112
- Updated
- 2021/12/16
- Product number
- ORS0004629
- Product name
- 1-[TRIS-(1-METHYLETHYL)SILYL]-1H-PYRROLO[2,3-B]PYRIDIN-5-OL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.83
- Updated
- 2021/12/16
- Product number
- CS-B1523
- Product name
- 1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
- Packaging
- 5g
- Price
- $336
- Updated
- 2021/12/16
- Product number
- 179557
- Product name
- 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol
- Packaging
- 1g
- Price
- $826
- Updated
- 2021/12/16
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Chemical Properties,Usage,Production
Synthesis
Add 10.8g (34mmol) of (1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid and 120mL of tetrahydrofuran to a round bottom flask equipped with a magnetic stirrer, an inert gas source and a separating funnel, and stir to dissolve; Add 34mL of 1mol/L sodium hydroxide solution and 4.60g (40.6mmol) of 30% hydrogen peroxide dropwise at 0°C. After the addition, React at 0°C for 1 hour and detect the reaction by TLC. Add 4.8g (20.24mmol) of sodium thiosulfate, adjust to pH=5 with 2mol/L hydrochloric acid, extract with ethyl acetate (2x200mL), combine the organic phases, wash with saturated brine in turn, dry with a sodium sulfate, and reduce Concentrate under pressure. The residue was purified by silica gel column chromatography [eluent: dichloromethane] to obtain 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 9.4g, yield 95.0%.
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol manufacturers
- Product
- 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 685514-01-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-02-14
- Product
- 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 685514-01-6
- Price
- US $0.00/KG
- Min. Order
- 0KG
- Purity
- 99%
- Supply Ability
- 100t
- Release date
- 2018-03-06