ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
- Product Name
- ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
- CAS No.
- 721-63-1
- Chemical Name
- ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
- Synonyms
- Penbutolol-d9A;2-[4-(trifluoroMethyl)phenyl]butanoate;Ethyl 4-(trifluoromethyl)benzeneacetate;ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE;ethyl 2-(4-(trifluoromethyl)phenyl)acetate;REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate;4-(Trifluoromethyl)benzeneacetic acid ethyl ester;(4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER;Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester
- CBNumber
- CB8190406
- Molecular Formula
- C11H11F3O2
- Formula Weight
- 232.2
- MOL File
- 721-63-1.mol
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Property
- Melting point:
- 34-35 °C
- Boiling point:
- 104-105 °C(Press: 7 Torr)
- Density
- 1.207
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- Solid
- color
- Colorless
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 2916340000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E1152
- Product name
- Ethyl 4-(Trifluoromethyl)phenylacetate
- Packaging
- 1G
- Price
- $59
- Updated
- 2025/07/31
- Product number
- E1152
- Product name
- Ethyl 4-(Trifluoromethyl)phenylacetate
- Packaging
- 5G
- Price
- $176
- Updated
- 2025/07/31
- Product number
- E930578
- Product name
- Ethyl 4-(Trifluoromethyl)phenylacetate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 072938
- Product name
- Ethyl 2-(4-(trifluoromethyl)phenyl)acetate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 076725
- Product name
- Ethyl 4-(Trifluoromethyl)phenylacetate
- Purity
- 99%
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Chemical Properties,Usage,Production
Synthesis
402-43-7
6148-64-7
721-63-1
General procedure: Under standard Schlenk operating conditions, the reaction system is first evacuated and backfilled three times with dry pure nitrogen. To a pre-dried Schlenk tube fitted with a magnetic stirring bar, palladium catalyst (see Tables 1 to 4 for specific types and amounts), ligand (see Tables 1 to 4), N,N-dimethylpyridin-4-amine (DMAP, see Tables 1 to 4), and monoethyl malonate potassium salt (see Tables 1 to 4) are added sequentially. Subsequently, the reaction tube was evacuated and backfilled with argon, and this process was repeated three times. Under argon protection, p-bromobenzotrifluoride (see Tables 1 through 4) and an appropriate amount of solvent (see Tables 1 through 4) were added via syringe. The reaction tube was sealed and stirred for 10 minutes at room temperature. Afterwards, the reaction tube is connected to a Schlenk line pre-filled with argon and placed in an oil bath preheated to 140-150°C and the reaction is stirred for 20-25 hours. After completion of the reaction, the reaction was cooled to room temperature, the reaction mixture was diluted with ether and the yield of ethyl 4-(trifluoromethyl)phenylacetate was determined by gas chromatography using 1,3-dimethoxybenzene as an internal standard.
References
[1] Tetrahedron, 2012, vol. 68, # 9, p. 2113 - 2120
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE manufacturers
- Product
- ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-30