ChemicalBook > CAS DataBase List > ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

Product Name: ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
CAS No.: 721-63-1
Chemical Name: ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
Synonyms: Penbutolol-d9A;2-[4-(trifluoroMethyl)phenyl]butanoate;Ethyl 4-(trifluoromethyl)benzeneacetate;ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE;ethyl 2-(4-(trifluoromethyl)phenyl)acetate;REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate;4-(Trifluoromethyl)benzeneacetic acid ethyl ester;(4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER;Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester
CBNumber: CB8190406
Molecular Formula: C11H11F3O2
Formula Weight: 232.2
MOL File: 721-63-1.mol

Less

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Property

Melting point:: 34-35 °C
Boiling point:: 104-105 °C(Press: 7 Torr)
Density: 1.207
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: Solid
color: Colorless

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2916340000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: E1152
Product name: Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging: 1G
Price: $59
Updated: 2025/07/31

TCI Chemical

Product number: E1152
Product name: Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging: 5G
Price: $176
Updated: 2025/07/31

TRC

Product number: E930578
Product name: Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 072938
Product name: Ethyl 2-(4-(trifluoromethyl)phenyl)acetate
Purity: 95+%
Packaging: 5g
Price: $74
Updated: 2021/12/16

Oakwood

Product number: 076725
Product name: Ethyl 4-(Trifluoromethyl)phenylacetate
Purity: 99%
Packaging: 5g
Price: $75
Updated: 2021/12/16

Less

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Chemical Properties,Usage,Production

Synthesis

402-43-7

6148-64-7

721-63-1

General procedure: Under standard Schlenk operating conditions, the reaction system is first evacuated and backfilled three times with dry pure nitrogen. To a pre-dried Schlenk tube fitted with a magnetic stirring bar, palladium catalyst (see Tables 1 to 4 for specific types and amounts), ligand (see Tables 1 to 4), N,N-dimethylpyridin-4-amine (DMAP, see Tables 1 to 4), and monoethyl malonate potassium salt (see Tables 1 to 4) are added sequentially. Subsequently, the reaction tube was evacuated and backfilled with argon, and this process was repeated three times. Under argon protection, p-bromobenzotrifluoride (see Tables 1 through 4) and an appropriate amount of solvent (see Tables 1 through 4) were added via syringe. The reaction tube was sealed and stirred for 10 minutes at room temperature. Afterwards, the reaction tube is connected to a Schlenk line pre-filled with argon and placed in an oil bath preheated to 140-150°C and the reaction is stirred for 20-25 hours. After completion of the reaction, the reaction was cooled to room temperature, the reaction mixture was diluted with ether and the yield of ethyl 4-(trifluoromethyl)phenylacetate was determined by gas chromatography using 1,3-dimethoxybenzene as an internal standard.

References

[1] Tetrahedron, 2012, vol. 68, # 9, p. 2113 - 2120

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Suppliers

Americas 1 Belgium 1 Canada 1 China 78 Europe 1 France 2 Germany 8 Hungary 1 India 6 Japan 2 Poland 1 Switzerland 2 United Kingdom 9 United States 28 Global 141

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Jovan Biochemical Technology Co. Ltd.

Tel: +86-021-61654350
Fax: +86-021-61654350
Email: 1245958370@qq.com
Country: China
ProdList: 2982
Advantage: 50

Changzhou Tianrui Pharmaceutical Technology Co., Ltd.

Tel: 0519-85386832 13382812559
Fax: 0519-85386832
Email: sales@cztrchem.com
Country: China
ProdList: 1185
Advantage: 56

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

DebyeTec.com Inc.

Tel: 18-086626237 18086626237
Fax: qq:2693528373
Email: 2693528373@qq.com
Country: China
ProdList: 2973
Advantage: 56

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
Fax: 1014988033@qq
Email: 1014988033@qq.com
Country: China
ProdList: 4941
Advantage: 55

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9754
Advantage: 58

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Huaian Hyperion pharmaceutical R&D Co.,Ltd.

Tel: 18114966287
Fax: -
Email: sales@hyperionpharm.com
Country: China
ProdList: 449
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9852
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10267
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: alfa10@alfachem.cn
Country: China
ProdList: 12921
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Baoji Guokang Healthchem Co., Ltd.

Tel: +86-0917-3909592 +86-13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9209
Advantage: 58

Baoji Guokang Healthchem co.,ltd

Tel: +8615604608665 15604608665
Email: dominicguo@gk-bio.com
Country: CHINA
ProdList: 9414
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Shanghai Jiegu Biotechnology Co., Ltd.

Tel: 021-51698675
Email: sales@jiejiegroup.com
Country: China
ProdList: 8020
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18717800556
Email: sales@finebiotech.com
Country: China
ProdList: 2182
Advantage: 58

Shanghai UCHEM Inc.

Tel: 18939844854
Fax: QQ3004479448
Email: sales6@myuchem.com
Country: China
ProdList: 4996
Advantage: 58

Shanghai Boer Chemical Reagent Co., LTD

Tel: 19102157732
Email: zhangmin@boerchina.net
Country: China
ProdList: 7849
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Shandong Welt Chem. Co.,Ltd.

Tel: 531-87153728 13805401165
Email: xufeng192@126.com
Country: China
ProdList: 3964
Advantage: 58

Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd.

Tel: 0371-55695890 15637198702
Email: 1677336983@qq.com
Country: China
ProdList: 13191
Advantage: 58

Less

View Lastest Price from ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-30

721-63-1, ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATERelated Search:

4-(Trifluoromethyl)phenyl acetate 4-(Trifluoromethyl)phenylacetic acid Ethyl phenylacetate RARECHEM AL BI 1336 ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 6-CHLORO-2,3-DIFLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID ETHYL ESTER ETHYL 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLACETATE ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE (S)-2-(2'-OXOCYCLOHEXYL)-2-(4''-TRIFLUOROMETHYLPHENYL)GLYCOLIC ACID ETHYL ESTER 3,3,4,4,4-PENTAFLUORO-2-HYDROXY-2-[4-(TRIFLUOROMETHYL)PHENYL]BUTYRIC ACID ETHYL ESTER RARECHEM AL BW 0991 2,3,6-TRIFLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID ETHYL ESTER ETHYL OXO-(4-TRIFLUOROMETHYLPHENYL)ACETATE ETHYL ALPHA-CYANO-2-NITRO-4-(TRIFLUOROMETHYL)PHENYLACETATE 3,3,3-TRIFLUORO-2-HYDROXY-2-(4-TRIFLUOROMETHYLPHENYL)PROPIONIC ACID ETHYL ESTER ETHYL 3,5-BIS(TRIFLUOROMETHYL)PHENYL ACETATE

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

ethyl 2-(4-(trifluoromethyl)phenyl)acetate

REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate

4-(Trifluoromethyl)benzeneacetic acid ethyl ester

2-[4-(trifluoroMethyl)phenyl]butanoate

Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester

(4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER

Ethyl 4-(trifluoromethyl)benzeneacetate

Penbutolol-d9A

721-63-1