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ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

Product Name
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
CAS No.
721-63-1
Chemical Name
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
Synonyms
Penbutolol-d9A;2-[4-(trifluoroMethyl)phenyl]butanoate;Ethyl 4-(trifluoromethyl)benzeneacetate;ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE;ethyl 2-(4-(trifluoromethyl)phenyl)acetate;REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate;4-(Trifluoromethyl)benzeneacetic acid ethyl ester;(4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER;Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester
CBNumber
CB8190406
Molecular Formula
C11H11F3O2
Formula Weight
232.2
MOL File
721-63-1.mol
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ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Property

Melting point:
34-35 °C
Boiling point:
104-105 °C(Press: 7 Torr)
Density 
1.207
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Solid
color 
Colorless
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
2916340000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1152
Product name
Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging
1G
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
E1152
Product name
Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging
5G
Price
$176
Updated
2025/07/31
TRC
Product number
E930578
Product name
Ethyl 4-(Trifluoromethyl)phenylacetate
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
072938
Product name
Ethyl 2-(4-(trifluoromethyl)phenyl)acetate
Purity
95+%
Packaging
5g
Price
$74
Updated
2021/12/16
Oakwood
Product number
076725
Product name
Ethyl 4-(Trifluoromethyl)phenylacetate
Purity
99%
Packaging
5g
Price
$75
Updated
2021/12/16
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ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Chemical Properties,Usage,Production

Synthesis

402-43-7

6148-64-7

721-63-1

General procedure: Under standard Schlenk operating conditions, the reaction system is first evacuated and backfilled three times with dry pure nitrogen. To a pre-dried Schlenk tube fitted with a magnetic stirring bar, palladium catalyst (see Tables 1 to 4 for specific types and amounts), ligand (see Tables 1 to 4), N,N-dimethylpyridin-4-amine (DMAP, see Tables 1 to 4), and monoethyl malonate potassium salt (see Tables 1 to 4) are added sequentially. Subsequently, the reaction tube was evacuated and backfilled with argon, and this process was repeated three times. Under argon protection, p-bromobenzotrifluoride (see Tables 1 through 4) and an appropriate amount of solvent (see Tables 1 through 4) were added via syringe. The reaction tube was sealed and stirred for 10 minutes at room temperature. Afterwards, the reaction tube is connected to a Schlenk line pre-filled with argon and placed in an oil bath preheated to 140-150°C and the reaction is stirred for 20-25 hours. After completion of the reaction, the reaction was cooled to room temperature, the reaction mixture was diluted with ether and the yield of ethyl 4-(trifluoromethyl)phenylacetate was determined by gas chromatography using 1,3-dimethoxybenzene as an internal standard.

References

[1] Tetrahedron, 2012, vol. 68, # 9, p. 2113 - 2120

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Suppliers

Americas 1 Belgium 1 Canada 1 China 78 Europe 1 France 2 Germany 8 Hungary 1 India 6 Japan 2 Poland 1 Switzerland 2 United Kingdom 9 United States 28 Global 141
Toronto Research Chemicals Inc.
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6668
Advantage
58
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View Lastest Price from ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 721-63-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-30

721-63-1, ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATERelated Search:

4-(Trifluoromethyl)phenyl acetate 4-(Trifluoromethyl)phenylacetic acid Ethyl phenylacetate RARECHEM AL BI 1336 ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE 6-CHLORO-2,3-DIFLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID ETHYL ESTER ETHYL 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLACETATE ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE (S)-2-(2'-OXOCYCLOHEXYL)-2-(4''-TRIFLUOROMETHYLPHENYL)GLYCOLIC ACID ETHYL ESTER 3,3,4,4,4-PENTAFLUORO-2-HYDROXY-2-[4-(TRIFLUOROMETHYL)PHENYL]BUTYRIC ACID ETHYL ESTER RARECHEM AL BW 0991 2,3,6-TRIFLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID ETHYL ESTER ETHYL OXO-(4-TRIFLUOROMETHYLPHENYL)ACETATE ETHYL ALPHA-CYANO-2-NITRO-4-(TRIFLUOROMETHYL)PHENYLACETATE 3,3,3-TRIFLUORO-2-HYDROXY-2-(4-TRIFLUOROMETHYLPHENYL)PROPIONIC ACID ETHYL ESTER ETHYL 3,5-BIS(TRIFLUOROMETHYL)PHENYL ACETATE

  • ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
  • ethyl 2-(4-(trifluoromethyl)phenyl)acetate
  • REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate
  • 4-(Trifluoromethyl)benzeneacetic acid ethyl ester
  • 2-[4-(trifluoroMethyl)phenyl]butanoate
  • Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester
  • (4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER
  • Ethyl 4-(trifluoromethyl)benzeneacetate
  • Penbutolol-d9A
  • 721-63-1