1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

Product Name: 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
CAS No.: 84468-24-6
Chemical Name: 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
Synonyms: C-1;IQSP;HA-100;HA-100 HYDROCHLORIDE;HA-100 DIHYDROCHLORIDE;1-(5-ISOQUINOLINESULFONYL)PIPERAZINE;1-(5-isoquinolinylsulfonyl)piperazine;1-(5-isoquinolinylsulfonyl)-piperazin;5-(Piperazin-1-ylsulfonyl)isoquinoline;Isoquinoline,5-(1-piperazinylsulfonyl)-
CBNumber: CB8193285
Molecular Formula: C13H15N3O2S
Formula Weight: 277.34
MOL File: 84468-24-6.mol

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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Property

Melting point:: >240°C (dec.)
Boiling point:: 497.4±55.0 °C(Predicted)
Density: 1.332±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO, Methanol, Water
form: Off-white lyophilized solid.
pka: 7.66±0.10(Predicted)
color: Off-White to Pale Yellow
CAS DataBase Reference: 84468-24-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: TM0862600

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris

Product number: 0543
Product name: C-1
Purity: ≥99%(HPLC)
Packaging: 10
Price: $163
Updated: 2021/12/16

Tocris

Product number: 0543
Product name: C-1
Purity: ≥99%(HPLC)
Packaging: 50
Price: $669
Updated: 2021/12/16

Usbiological

Product number: 366887
Product name: HA-100 Dihydrochloride
Packaging: 25mg
Price: $505
Updated: 2021/12/16

Usbiological

Product number: 254849
Product name: C-1
Packaging: 10mg
Price: $409
Updated: 2021/12/16

ApexBio Technology

Product number: B6343
Product name: C-1
Packaging: 25mg
Price: $441
Updated: 2021/12/16

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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Crystalline Solid

Uses

Exhibited potent inhibition toward protein kinase C and cyclic nucleotide dependent protein kinases

Definition

ChEBI: 5-(1-piperazinylsulfonyl)isoquinoline is a member of isoquinolines.

Biological Activity

Inhibitor of protein kinase C. Vasodilator.

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE Suppliers

Canada 1 China 61 Germany 2 South Korea 1 Switzerland 3 United Kingdom 2 United States 24 Global 94

3B Pharmachem (Wuhan) International Co.,Ltd.

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BOC Sciences

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Shanghai Raise Chemical Technology Co.,Ltd

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EMMX Biotechnology LLC

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Shanghai EFE Biological Technology Co., Ltd.

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Twochem Co.Ltd.

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Yujinpharma(Tianjin) Technology Co.,Ltd.

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Angel Pharmatech, Ltd.

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Fan De(Beijing) Biotechnology Co., Ltd.

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84468-24-6, 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDERelated Search:

Histamine dihydrochloride Piperazine 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE (S)-5-(3-Isobutyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride (S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE 1-(8-CHLORO-5-ISOQUINOLINE-SULFONYL)PIPERAZINE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE (R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride (S) 5-(3-Isopropyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride (S)-5-(3-Benzyl-piperazine-1-sulfonyl)-isoquinoline dihydrochloride H-7 DIHYDROCHLORIDE 1-(8-CHLORO-5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

1-(5-isoquinolinylsulfonyl)-piperazin

1-(5-isoquinolinylsulfonyl)piperazine

1-(5-ISOQUINOLINYLSULFONYL)PIPERAZINE 2HCL

1-(5-ISOQUINOLINYLSULFONYL)-PIPERAZINE HYDROCHLORIDE

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

C-1

HA-100

HA-100 DIHYDROCHLORIDE

HA-100 HYDROCHLORIDE

1-(5-isoquinolinesulfonyl)piperazine hydrochloride

1-[(Isoquinolin-5-yl)sulfonyl]piperazine

IQSP

(141543-63-7) 1-(5-isoquinolinesulfonyl)piperazine hydrochloride

Isoquinoline,5-(1-piperazinylsulfonyl)-

5-(Piperazin-1-ylsulfonyl)isoquinoline

protein,PKC,Rho-associated kinase,ROCK,kinase,PKG,HA100,inhibit,Inhibitor,Myosin,HA 100,MLCK,HA-100,Rho-associated protein kinase,ROK,PKA,Rho-kinase,Protein kinase C,Protein kinase A

84468-24-6

C13H17Cl2N3O2S

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Kinase/Phosphatase Biology

Protein Kinase A, C and myosin light chain kinase (PKA, PKC and MLCK)

Serine/Threonine Kinase Inhibitors

Protein Kinase Inhibitors and Activators

Protein Kinase