ChemicalBook > CAS DataBase List > 4-acetylbutyric acid

4-acetylbutyric acid

Product Name: 4-acetylbutyric acid
CAS No.: 3128-06-1
Chemical Name: 4-acetylbutyric acid
Synonyms: 5-OXOHEXANOIC ACID;4-ACETYLBUTYRIC ACID;Glurate;5-Oxohexanoate;Ketohexanoicacid;5-oxo-hexanoicaci;5-Ketocaproic acid;5-KETOHEXANOIC ACID;RARECHEM AL BO 0242;4-acetylbutyri acid
CBNumber: CB8196332
Molecular Formula: C6H10O3
Formula Weight: 130.14
MOL File: 3128-06-1.mol

Less

4-acetylbutyric acid Property

Melting point:: 13-14 °C(lit.)
Boiling point:: 274-275 °C(lit.)
Density: 1.09 g/mL at 25 °C(lit.)
refractive index: n20/D 1.4451(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Off-White Semi-Solid
pka: 4.63±0.10(Predicted)
color: Colorless to Red to Green
Water Solubility: Slightly soluble in water, chloroform and methanol.
BRN: 385840
CAS DataBase Reference: 3128-06-1(CAS DataBase Reference)
NIST Chemistry Reference: 4-Acetylbutyric acid(3128-06-1)
EPA Substance Registry System: Hexanoic acid, 5-oxo- (3128-06-1)

Less

Safety

Risk Statements: 36/38
Safety Statements: 26-36-24/25
WGK Germany: 3
TSCA: Yes
HS Code: 29183000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A13204
Product name: 4-Acetylbutyric acid
Purity: 97%
Packaging: 5g
Price: $88.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: A13204
Product name: 4-Acetylbutyric acid
Purity: 97%
Packaging: 25g
Price: $320
Updated: 2025/07/31

TCI Chemical

Product number: K0014
Product name: 5-Oxohexanoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $199
Updated: 2025/07/31

TCI Chemical

Product number: K0014
Product name: 5-Oxohexanoic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $642
Updated: 2025/07/31

TRC

Product number: A168440
Product name: 4-Acetylbutyric acid
Packaging: 50g
Price: $290
Updated: 2021/12/16

Less

4-acetylbutyric acid Chemical Properties,Usage,Production

Chemical Properties

Liquid

Uses

4-Acetylbutyric acid is used in the synthesis of selective indomethacin analogues for AKR1C3 inhibition in the treatment of castrate-resistant prostate cancer. It is also used to prepare PARP inhibitors for the treatment of cancer.

Uses

4-Acetylbutyric acid may be used in the preparation of the following compounds:
5-hydroxyhexanoic acid
6-methyl1-3,4-dihydro-pyran-2-one, precursor for 5-acetyl-tetrahydro-2-(3H)-furanone
substituted N-aminolactams
(±)-5-methyl-δ-valerolactone
Crystal Structure of T.th. HB8 O-acetylserine sulfhydrylase Complexed with 4-Acetylbutyric acid

Definition

ChEBI: 4-acetylbutyric acid is a medium-chain fatty acid comprising hexanoic acid carrying a 5-oxo group. It has a role as a bacterial xenobiotic metabolite. It is a 5-oxo monocarboxylic acid, an oxo fatty acid, a medium-chain fatty acid and a straight-chain fatty acid. It derives from a hexanoic acid. It is a conjugate acid of a 5-oxohexanoate.

Synthesis Reference(s)

Synthetic Communications, 10, p. 205, 1980 DOI: 10.1080/00397918008064223
Tetrahedron, 41, p. 2163, 1985 DOI: 10.1016/S0040-4020(01)96588-3

4-acetylbutyric acid Preparation Products And Raw materials

Raw materials

1,3-Cyclohexanedione

Preparation Products

Less

4-acetylbutyric acid Suppliers

Americas 1 China 105 Europe 1 Germany 4 India 4 Japan 1 Switzerland 1 United Kingdom 5 United States 16 Global 138

Chongqing TianyiHenghua Technology Co., Ltd.

Tel: 15086758486; 15086758486
Fax: -
Email: chemtyhh@163.com
Country: China
ProdList: 93
Advantage: 58

Anyang Xiyan Technology Co., LTD

Tel: 17525889330
Email: 17525889330@163.com
Country: China
ProdList: 7849
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chembon Pharmaceutical Co., Ltd.

Tel: 028-84252981
Fax: +86-28-84252965
Email: sales@chembon.com.cn
Country: China
ProdList: 850
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai YueChen International Trading Co. Ltd

Tel: 021-67256163
Fax: 021-67256081
Email: shanghailechen@163.com
Country: China
ProdList: 170
Advantage: 55

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Fax: 2880152141(QQ)
Email: youchemicals@gmail.com
Country: China
ProdList: 1839
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9986
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 13482386415
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 896
Advantage: 50

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10410
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886750 13927877953
Fax: 0751-2886750
Email: 3005811397@qq.com
Country: China
ProdList: 13305
Advantage: 58

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Nanjing ChemLin Chemical Industry Co., Ltd.

Tel: 025-83453353
Fax: 025-83453353
Email: nj.chemlin@chemlin.com.cn
Country: CHINA
ProdList: 853
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9992
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Wuhan yuqing jiaheng pharmaceutical co. LTD

Tel: 027-83855389 13545340383
Fax: 027-83855389
Email: 2586905842@qq.com
Country: China
ProdList: 995
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10237
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

Zhejiang Zetian Fine Chemical Co., Ltd

Tel: 0571-87682782 18957127338
Fax: QQ:3007632051
Email: sales@zetchem.com
Country: China
ProdList: 476
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Less

View Lastest Price from 4-acetylbutyric acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-acetylbutyri acid 3128-06-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-11

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Ketocaproic acid 3128-06-1
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Oxohexanoate 3128-06-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

3128-06-1, 4-acetylbutyric acidRelated Search:

Indole-3-butyric acid Allyl hexanoate EPA Methyl hexanoate CELLULOSE ACETATE BUTYRATE 4-Aminobutyric acid Folic acid 6-Aminocaproic acid Chlorambucil Hexyl hexanoate Butyric Acid Hydrocortisone-17-butyrate Ethyl Hexanoate Citric acid Ascoric Acid 4-BENZOYLBUTYRIC ACID Ethyl 4-acetylbutyrate DIETHYL 2-ACETYLGLUTARATE

5-Oxohexanoate

5-OXOHEXANOIC ACID

5-KETOHEXANOIC ACID

4-ACETYLBUTYRIC ACID

5-Ketohexanoic acid~5-Oxohexanoic acid

Ketohexanoicacid

γ-Acetylbutyric acid

4-Acetylbutyric acid,5-Ketohexanoic acid

RARECHEM AL BO 0242

5-Ketocaproic acid

5-oxo-hexanoicaci

delta-Ketocaproic acid

delta-Oxocaproic acid

gamma-Acetylbutyric acid

Hexanoic acid, 5-oxo-

5-OxohexanoicAcid&gt

4-Acetylbutyric acid-97%

Glurate

4-acetylbutyri acid

3128-06-1

3128-O6-1

128-06-1

CH3COCH23CO2H

Organic Building Blocks

CARBOXYLIC ACID

Carbonyl Compounds

Building Blocks

Carboxylic Acids