Methyl eugenol
Description Occurrence Application- Product Name
- Methyl eugenol
- CAS No.
- 93-15-2
- Chemical Name
- Methyl eugenol
- Synonyms
- 4-ALLYL-1,2-DIMETHOXYBENZENE;EUGENOL METHYL ETHER;1,2-DIMETHOXY-4-(2-PROPENYL)BENZENE;EUGENYL METHYL ETHER;jiaji;O-Methyleugenol;Benzene, 1,2-dimethoxy-4-(2-propenyl)-;4-Allylveratrol;3-METHYLEUGENOL;4-ALLYLVERATROLE
- CBNumber
- CB8198972
- Molecular Formula
- C11H14O2
- Formula Weight
- 178.23
- MOL File
- 93-15-2.mol
Methyl eugenol Property
- Melting point:
- -4 °C (lit.)
- Boiling point:
- 254-255 °C (lit.)
- Density
- 1.036 g/mL at 25 °C (lit.)
- vapor pressure
- 0.463-1.983Pa at 25℃
- refractive index
- n20/D 1.534(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- 0.5g/l
- form
- Oil
- color
- Colourless to Pale Yellow
- Odor
- at 1.00 % in dipropylene glycol. sweet fresh warm spicy clove carnation cinnamon
- Odor Type
- spicy
- Water Solubility
- insoluble
- Merck
- 14,6073
- BRN
- 1910871
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- ZYEMGPIYFIJGTP-UHFFFAOYSA-N
- LogP
- 2.74-3.03
- CAS DataBase Reference
- 93-15-2(CAS DataBase Reference)
- IARC
- 2B (Vol. 101) 2013
- NIST Chemistry Reference
- Benzene, 1,2-dimethoxy-4-(2-propenyl)-(93-15-2)
- EPA Substance Registry System
- Methyleugenol (93-15-2)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-40
- Safety Statements
- 26-36/37/39
- WGK Germany
- 1
- RTECS
- CY2450000
- HS Code
- 29093090
- Hazardous Substances Data
- 93-15-2(Hazardous Substances Data)
- Toxicity
- LD50 orally in rats: 1560 mg/kg (Jenner)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- W247502
- Product name
- Methyl eugenol
- Purity
- ≥98%, FCC
- Packaging
- 1kg
- Price
- $101
- Updated
- 2024/03/01
- Product number
- W247502
- Product name
- Methyl eugenol
- Purity
- ≥98%, FCC
- Packaging
- 10Kg
- Price
- $769
- Updated
- 2024/03/01
- Product number
- W247502
- Product name
- Methyl eugenol
- Purity
- ≥98%, FCC
- Packaging
- 25kg
- Price
- $1740
- Updated
- 2024/03/01
- Product number
- 284424
- Product name
- 4-Allyl-1,2-dimethoxybenzene
- Purity
- 99%
- Packaging
- 5g
- Price
- $30.2
- Updated
- 2024/03/01
- Product number
- 04607
- Product name
- Methyl eugenol
- Purity
- analytical standard
- Packaging
- 50mg
- Price
- $116
- Updated
- 2024/03/01
Methyl eugenol Chemical Properties,Usage,Production
Description
Methyleugenol (ME) (4-alkyl-1, 2-dimethoxybenzene-carboxylate) is a natural chemical compound classified as a type of phenylpropanoid and it is the methyl ether of eugenol. ME is a widely distributed natural plant product and occurs in > 200 plant species in 32 families found mainly in the tropics. It is consumed by humans and animals in many plants and fruits (e.g., anise, nutmeg, basil, blackberry essence, bananas, and citrus), and ME is a yellowish, oily, naturally occurring liquid with a clove-like aroma and is present in many essential oils.
Occurrence
Methyl eugenol is not very common in higher concentrations in the essential oils of Ocimum species. However, 20% methyl eugenol has been found in the oil of O. sanctum (Hegnauer 1966). Methyl eugenol has been detected as the main compound in an essential oil of O.basilicum var. minimum of Taiwanese origin (42.9-64.3%) and in the stem oil of O.basilicum (53.1%) of the same origin (Cheng and Liu 1983). In an oil of O.gratissimum of Brazilian origin, 46.8% methyl eugenol was found (Vostrowsky 1990). A high methyl eugenol concentration (24.7%) was reported by Brophy and Jogia (1986) from plant material of O.basilicum grown locally in Fiji.
Application
Methyl eugenol is used as a flavouring agent in jellies, baked goods, non-alcoholic beverages, chewing gum, candy, puddings, relishes and ice cream and it is also widely used as a fragrance ingredient in perfumes (0.3–0.8%), creams and lotions (0.01–0.05%), toiletries and detergents. Moreover, ME has been used as an anaesthetic in rodents and it also is used as an insect attractant in combination with insecticides.
Methyleugenol is also a component of several essential oils that are sold for use in aromatherapy, massage oils and alternative medicines. Some essential oils, including citronella (Cymbopogon spp.), basil (Ocimum spp.), bay (Laurus nobilis) and tea tree (Melaleuca spp.), which may contain a high percentage of methyleugenol are used as fragrances in consumer products, such as personal care products and household cleaners. For example, citronella oil, which may contain methyleugenol, is an active ingredient in some commercially available personal insect repellent lotions and sprays that are applied to the skin and it is also used in outdoor candles and torches as an ambient insect repellent.
Description
Clear colorless to pale yellow liquid. Spicy,earthy odor. Bitter burning taste. This chemical is combustible. Molecular weight = 178.23; Specific gravity 5 1.0396at 20℃; Vapor density 5 .1.0; Boiling point = 249℃;254.7℃ at 760 mmHg; Melting point 5 2 4℃; Vaporpressure 5 0.02 mmHg at 20℃; 1 mmHg at 85℃; Flashpoint 5 99℃; 109℃. Hazard Identification (based on NFPA704 M Rating System): Health 2; Flammability 1; Reactivity0. Practically insoluble in water; solubility 5 ,1 mg/mL at66F; 500 mg/L.
Chemical Properties
colourless to light yellow liquid
Chemical Properties
Clear colorless to pale yellow liquid. Spicy, earthy odor. Bitter burning taste. This chemical is combustible.
Chemical Properties
Eugenol Methyl Ethe occurs in numerous essential oils, sometimes at a very high concentration. The ether is an almost colorless liquid with a mild-spicy, slightly herbal odor. It is prepared by methylation of eugenol and is used in perfumery (e.g., in carnation and lilac compositions) and in flavor compositions.
Chemical Properties
Eugenyl methyl ether has a delicate clove–carnation odor with a bitter, burning taste.
Occurrence
Reported in the essential oils of Myrtaceae and Luraceae; it was identifed originally in the essential oil from roots of Asarum europaeum L and Asarum canadense L Subsequently, it was identifed as the main constituent of the oil from wood of Dacrydium franklinii Hook (97 5%), in Melaleuca bracteata F v M (leaves, 90 to 95%), in Cinnamomum oliveri Bail (leaves, 90 to 95%), and as a minor constituent in the oils of betel, citronella, Japanese calamus, pimenta, hyacinth, rose, basil, bay, cajeput and others Reported found in heated blackberry, pepper, lovage seed, chervil, lemon balm, alpinia species, clove buds, nutmeg, pepper, mace, tarragon, Ocimum sanctum, laurel, myrtle leaf and berry, rosemary, pimento berry and mastic gum leaf oil
Uses
Fragrance ingredient in perfumes, toiletries and detergents; flavor ingredient in baked goods.
Uses
Methyleugenol is a phenylpropene that is commonly found in plants such as nutmeg, pimento, lemongrass, tarragon, basil, star anise, and fennel. Methyleugenol has been shown to inhibit histone deacetylase (HDAC) activity in the human colon carcinoma cell line HT29. Compounds that exhibit HDAC-inhibitory properties or disrupt the HDAC complex have potential applications in cancer therapy and chemoprevention. In addition, Methyleugenol is a flavoring agent often used in consumer products such as jellies, baked goods, beverages,chewing gums, ice cream, and fragrance.
Uses
Methyl eugenol may be used as an analytical reference standard for the quantification of the analyte in the following:????????
- Essential oil of Pimenta pseudocaryophyllus using high-performance liquid chromatography (HPLC). The purity of the extracted compound is then determined by gas chromatography coupled to flame ionization detector (GC/FID).???????
- Stem bark of Cinnamomum zeylanicum Blume using reversed-phase high-performance liquid chromatography (RP-HPLC) with UV-visible detection.???????
- Rosa hybrida using gas-chromatography coupled to mass spectrometry (GC-MS) technique.
Definition
ChEBI: O-methyleugenol is a phenylpropanoid. It is functionally related to a eugenol.
Preparation
Usually prepared by methylation of eugenol.
Aroma threshold values
Detection: 68 ppb to 8 5 ppm.
Taste threshold values
Taste characteristics at 5.0 ppm: spice, cinnamon and clove, mouth tingle, fresh, peppery and woody.
General Description
Clear colorless to pale yellow liquid with a spicy earthy odor. Bitter burning taste.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Methyl eugenol is incompatible with strong oxidizers . May react exothermically with reducing agents to release hydrogen gas.
Hazard
Possible carcinogen.
Fire Hazard
Methyl eugenol is combustible.
Biochem/physiol Actions
Taste at 1.5 ppm
Safety Profile
Confirmed carcinogen. Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. A skin irritant. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. Some other alkenylbenzenes have carcinogenic activity. See also EUGENOL, ALLYL COMPOUNDS, and ETHERS
Potential Exposure
Methyl eugenol is a naturally occurring substance found in the essential oils of several plant species. Methyleugenol is used as a flavoring agent in jellies, baked goods, nonalcoholic beverages, chewing gum, candy, pudding, relish, and ice cream. Methyleugenol has been used as an anesthetic in rodents. It also is used as an insect attractant in combination with insecticides.
First aid
Eyes: Consideration should be given to the skin,eyes, and respiratory tract (lung function tests) in any placement or periodic examinations. Evaluation by a qualifiedallergist, including careful exposure history and special testing, may help diagnose skin or respiratory tract allergy.
Carcinogenicity
Methyleugenol is reasonably anticipated to be a human carcinogenbased on sufficient evidence of carcinogenicity from studies in experimental animals.
Solubility in organics
Soluble in alcohol and oils
storage
Color Code—Green: General storage may be used.You should protect this material from exposure to light, andstore it under ambient temperatures
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Recrystallise the ether from hexane at low temperature and redistil it (preferably in vacuo). [Hillmer & Schorning Z Phys Chem [A] 167 407 1934, Briner & Fliszár Helv Chim Acta 42 2063 1959, Beilstein 6 H 963, 6 IV 6337.]
Incompatibilities
Methyleugenol is Incompatible with strong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact with reducing agents may cause the release of hydrogen gas
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.
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View Lastest Price from Methyl eugenol manufacturers
- Product
- Methyl eugenol 93-15-2
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-05
- Product
- Methyl eugenol 93-15-2
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-29
- Product
- Methyl eugenol 93-15-2
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- More than 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-05-27