Talaporfin sodium
- Product Name
- Talaporfin sodium
- CAS No.
- 220201-34-3
- Chemical Name
- Talaporfin sodium
- Synonyms
- NPe6;Laserphyrin;D01985;ME2906;Taporfin sodiuM;Laserphyrin (tn);Talaporfin sodium;Talaporfin sodiuM salt;Talaporfin sodium (jan/usan);Mono-L-Aspartyl Chlorin e6 Tetrasodium Salt (NPe6)
- CBNumber
- CB82128759
- Molecular Formula
- C38H42N5NaO9
- Formula Weight
- 735.77
- MOL File
- 220201-34-3.mol
Talaporfin sodium Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO:2.0(Max Conc. mg/mL);2.5(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);62.52(Max Conc. mM) - form
- A solid
- color
- Purple to black
N-Bromosuccinimide Price
- Product number
- SML3520
- Product name
- Talaporfin sodium
- Purity
- ≥95% (HPLC)
- Packaging
- 1 unit
- Price
- $824
- Updated
- 2025/07/31
- Product number
- API0005324
- Product name
- TALAPORFIN SODIUM
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2001.04
- Updated
- 2021/12/16
- Product number
- Y1938
- Product name
- Talaporfinsodium
- Packaging
- 10mg
- Price
- $585
- Updated
- 2021/12/16
- Product number
- Y1938
- Product name
- Talaporfinsodium
- Packaging
- 5mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- API0005324
- Product name
- TALAPORFIN SODIUM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $345.4
- Updated
- 2021/12/16
Talaporfin sodium Chemical Properties,Usage,Production
Uses
Talaporfin sodium is photosensitizer for use in photodynamic therapy to destroy tumor tissue.
in vivo
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs) [1].
Labeling in vivo:
1. Use the rat brain tumor model produced by the inoculation of resuspended tumor cells into the frontal rat brain. Feed animals according to your normal protocol.
2. Intravenous injection of 5 mg/kg body weight talaporfin sodium, the concentration of the talaporfin sodium is 5 mg/1 ml 0.9% saline.
3. For the control group, intraperitoneal injection of 100 mg/kg body weight 5-ALA, the concentration of the 5-ALA is 20 mg/1 ml 0.9% saline.
4. Obtain the tissue samples corresponding to the tumor (or edema) brain tissue with 5 mm thickness.
5. The samples are well homogenized with 1 ml of 100% dimethyl sulfoxide (DMSO) and the 100 ul aliquots of the supernatant are put into each well of a 96-well plate.
6. Measure the relative fluorescence intensities of the samples by using a microplate readerin emission wavelength of 670 ±10 nm. The relative fluorescence intensities of the samples (a.u.) were normalized to the relative fluorescence intensities per 1 g-weight of the samples (a.u.).
| Animal Model: | Rat brain tumor model[1] |
| Dosage: | 5 mg/kg |
| Administration: | Intravenous injection |
| Result: | Showed high fluorescence intensity and retention in brain tumor differentiated from vasogenic edema. |
Talaporfin sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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