ChemicalBook > CAS DataBase List > Talaporfin sodium

Talaporfin sodium

Product Name
Talaporfin sodium
CAS No.
220201-34-3
Chemical Name
Talaporfin sodium
Synonyms
NPe6;Laserphyrin;D01985;ME2906;Taporfin sodiuM;Laserphyrin (tn);Talaporfin sodium;Talaporfin sodiuM salt;Talaporfin sodium (jan/usan);Mono-L-Aspartyl Chlorin e6 Tetrasodium Salt (NPe6)
CBNumber
CB82128759
Molecular Formula
C38H42N5NaO9
Formula Weight
735.77
MOL File
220201-34-3.mol
More
Less

Talaporfin sodium Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO:2.0(Max Conc. mg/mL);2.5(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);62.52(Max Conc. mM)
form 
A solid
color 
Purple to black
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3520
Product name
Talaporfin sodium
Purity
≥95% (HPLC)
Packaging
1 unit
Price
$824
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
API0005324
Product name
TALAPORFIN SODIUM
Purity
95.00%
Packaging
5G
Price
$2001.04
Updated
2021/12/16
AK Scientific
Product number
Y1938
Product name
Talaporfinsodium
Packaging
10mg
Price
$585
Updated
2021/12/16
AK Scientific
Product number
Y1938
Product name
Talaporfinsodium
Packaging
5mg
Price
$325
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005324
Product name
TALAPORFIN SODIUM
Purity
95.00%
Packaging
5MG
Price
$345.4
Updated
2021/12/16
More
Less

Talaporfin sodium Chemical Properties,Usage,Production

Uses

Talaporfin sodium is photosensitizer for use in photodynamic therapy to destroy tumor tissue.

in vivo

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs) [1].
Labeling in vivo:
1. Use the rat brain tumor model produced by the inoculation of resuspended tumor cells into the frontal rat brain. Feed animals according to your normal protocol.
2. Intravenous injection of 5 mg/kg body weight talaporfin sodium, the concentration of the talaporfin sodium is 5 mg/1 ml 0.9% saline.
3. For the control group, intraperitoneal injection of 100 mg/kg body weight 5-ALA, the concentration of the 5-ALA is 20 mg/1 ml 0.9% saline.
4. Obtain the tissue samples corresponding to the tumor (or edema) brain tissue with 5 mm thickness.
5. The samples are well homogenized with 1 ml of 100% dimethyl sulfoxide (DMSO) and the 100 ul aliquots of the supernatant are put into each well of a 96-well plate.
6. Measure the relative fluorescence intensities of the samples by using a microplate readerin emission wavelength of 670 ±10 nm. The relative fluorescence intensities of the samples (a.u.) were normalized to the relative fluorescence intensities per 1 g-weight of the samples (a.u.).

Animal Model:Rat brain tumor model[1]
Dosage:5 mg/kg
Administration:Intravenous injection
Result:Showed high fluorescence intensity and retention in brain tumor differentiated from vasogenic edema.

Talaporfin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Talaporfin sodium Suppliers

Shanghai Xianhui Pharmaceutical Co., Ltd.
Tel
13564796979
Fax
86 21 67792654
Email
shxh2006@aliyun.com
Country
China
ProdList
32
Advantage
62
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Shanghai Brain Biotechnology Co., Ltd.
Tel
13564638271
Fax
021-68948280
Email
shhjiang1977@163.com
Country
China
ProdList
2987
Advantage
55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Aktin Chemicals, Inc.
Tel
028-85159085
Email
info@aktinchem.com
Country
China
ProdList
1860
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Wuhan Brin Technology Co., Ltd.
Tel
3456065315 13260619011
Email
3456065315@qq.com
Country
China
ProdList
2192
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
029-029-81123119 17391733320
Email
1021@dideu.com
Country
China
ProdList
9995
Advantage
58
Chongqing Botao Biotechnology Co., LTD
Tel
15223382610
Email
danny@chemdad.com
Country
China
ProdList
2032
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29423
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11146
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Shanghai Chenchu Chemical Co.,ltd.
Tel
13651748127
Email
2684615189@qq.com
Country
China
ProdList
224
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
14580
Advantage
58
Xingji Pharmaceutical (Shanghai) Co., Ltd
Tel
15705593425
Email
support@utgene.com
Country
China
ProdList
316
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
DAYANG CHEM (HANGZHOU) CO.,LTD
Tel
+86-88938639 +86-17705817739
Email
info@dycnchem.com
Country
China
ProdList
53899
Advantage
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
Email
cooperation@kean-chem.com
Country
China
ProdList
40066
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
+undefined18143011203
Email
info@chemextension.com
Country
China
ProdList
42056
Advantage
58
Shanghai Acmec Biochemical Technology Co., Ltd.
Tel
+86-18621343501; +undefined18621343501
Email
product@acmec-e.com
Country
China
ProdList
33338
Advantage
58
Nanjing Doge Biomedical Technology Co., Ltd
Tel
+86-25-58227606 +86-15305155328
Email
sales@dogechemical.com
Country
China
ProdList
4128
Advantage
58
Guangzhou Yiran Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
ProdList
141
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

220201-34-3, Talaporfin sodiumRelated Search:


  • D01985
  • Laserphyrin
  • Laserphyrin (tn)
  • Talaporfin sodium (jan/usan)
  • N-[2-[(7S,8S)-3-Carboxy-7-(2-carboxyethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetraMethyl-21H
  • N-[2-[(7S,8S)-3-Carboxy-7-(2-carboxyethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetraMethyl-21H,23H-porphin-5-yl]acetyl]-L-aspartic acid sodiuM salt
  • Talaporfin sodiuM salt
  • Taporfin sodiuM
  • TetrasodiuM (2S)-2-((((7S,8S)-3-carboxylato-7-(2-carboxylatoethyl)-13-ethenyl-18-ethyl-2,8,12,17-tet
  • Talaporfin sodium
  • Tetrasodium (2S)-2-((((7S,8S)-3-carboxylato-7-(2-carboxylatoethyl)-13-ethenyl-18-ethyl-2,8,12,17-tetramethyl-7,8-dihydroporphyrin-5-yl)acetyl)amino)butanedioate
  • ME2906
  • NPe6
  • Mono-L-Aspartyl Chlorin e6 Tetrasodium Salt (NPe6)
  • 220201-34-3
  • C38H37N5Na4O9