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Talaporfin sodium

Product Name
Talaporfin sodium
CAS No.
220201-34-3
Chemical Name
Talaporfin sodium
Synonyms
NPe6;Laserphyrin;D01985;ME2906;Taporfin sodiuM;Laserphyrin (tn);Talaporfin sodium;Talaporfin sodiuM salt;Talaporfin sodium (jan/usan);Mono-L-Aspartyl Chlorin e6 Tetrasodium Salt (NPe6)
CBNumber
CB82128759
Molecular Formula
C38H42N5NaO9
Formula Weight
735.77
MOL File
220201-34-3.mol
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Talaporfin sodium Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO:2.0(Max Conc. mg/mL);2.5(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);62.52(Max Conc. mM)
form 
A solid
color 
Purple to black
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3520
Product name
Talaporfin sodium
Purity
≥95% (HPLC)
Packaging
1 unit
Price
$824
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
API0005324
Product name
TALAPORFIN SODIUM
Purity
95.00%
Packaging
5G
Price
$2001.04
Updated
2021/12/16
AK Scientific
Product number
Y1938
Product name
Talaporfinsodium
Packaging
10mg
Price
$585
Updated
2021/12/16
AK Scientific
Product number
Y1938
Product name
Talaporfinsodium
Packaging
5mg
Price
$325
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005324
Product name
TALAPORFIN SODIUM
Purity
95.00%
Packaging
5MG
Price
$345.4
Updated
2021/12/16
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Talaporfin sodium Chemical Properties,Usage,Production

Uses

Talaporfin sodium is photosensitizer for use in photodynamic therapy to destroy tumor tissue.

in vivo

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs) [1].
Labeling in vivo:
1. Use the rat brain tumor model produced by the inoculation of resuspended tumor cells into the frontal rat brain. Feed animals according to your normal protocol.
2. Intravenous injection of 5 mg/kg body weight talaporfin sodium, the concentration of the talaporfin sodium is 5 mg/1 ml 0.9% saline.
3. For the control group, intraperitoneal injection of 100 mg/kg body weight 5-ALA, the concentration of the 5-ALA is 20 mg/1 ml 0.9% saline.
4. Obtain the tissue samples corresponding to the tumor (or edema) brain tissue with 5 mm thickness.
5. The samples are well homogenized with 1 ml of 100% dimethyl sulfoxide (DMSO) and the 100 ul aliquots of the supernatant are put into each well of a 96-well plate.
6. Measure the relative fluorescence intensities of the samples by using a microplate readerin emission wavelength of 670 ±10 nm. The relative fluorescence intensities of the samples (a.u.) were normalized to the relative fluorescence intensities per 1 g-weight of the samples (a.u.).

Animal Model:Rat brain tumor model[1]
Dosage:5 mg/kg
Administration:Intravenous injection
Result:Showed high fluorescence intensity and retention in brain tumor differentiated from vasogenic edema.

Talaporfin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Talaporfin sodium Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

220201-34-3, Talaporfin sodiumRelated Search:


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  • Laserphyrin
  • Laserphyrin (tn)
  • Talaporfin sodium (jan/usan)
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  • TetrasodiuM (2S)-2-((((7S,8S)-3-carboxylato-7-(2-carboxylatoethyl)-13-ethenyl-18-ethyl-2,8,12,17-tet
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  • ME2906
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  • 220201-34-3
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