2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
- Product Name
- 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
- CAS No.
- 957198-30-0
- Chemical Name
- 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
- Synonyms
- 2-(Morpholino)pyrimidine-5-boronic acid pinacol ester;2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester;2-(4-Morphelino)pyrimidine-5-boronic acid pinacol ester;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol eser;9 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester;2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol ester 97%;2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;4-(5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidin-2-yl)Morpholine;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER ISO 9001:2015 REACH
- CBNumber
- CB8233024
- Molecular Formula
- C14H22BN3O3
- Formula Weight
- 291.15
- MOL File
- 957198-30-0.mol
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Property
- Density
- 1.16
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BML00298
- Product name
- 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $330
- Updated
- 2025/07/31
- Product number
- M725233
- Product name
- 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M725233
- Product name
- 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 281839
- Product name
- 2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester
- Packaging
- 500mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- AMTB1306
- Product name
- 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
- Packaging
- 250mg
- Price
- $24
- Updated
- 2021/12/16
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production
Synthesis
84539-22-0
73183-34-3
957198-30-0
4-(5-bromopyrimidin-2-yl)morpholine (2.01 g, 8.23 mmol), pinacol ester of bis(boronic acid) (3.8 g, 15 mmol), potassium acetate (2.5 g, 25 mmol) and Pd(dppf)Cl2 (0.61 g, 0.83 mmol) were mixed in 1,4-dioxane (30 mL). The reaction mixture was stirred at 90 °C overnight under nitrogen protection. After completion of the reaction, the mixture was cooled to room temperature and diluted with water (20 mL). The reaction mixture was extracted with dichloromethane (30 mL x 3). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with petroleum ether/ethyl acetate (v/v = 7/3) as eluent to give a white solid product (0.4 g, 88% yield). m/z MS (ESI, cationic): 292.0 [M + 1]+.
References
[1] Patent: WO2016/615, 2016, A1. Location in patent: Paragraph 00730
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER manufacturers
- Product
- 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-12
- Product
- 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09