ChemicalBook > CAS DataBase List > 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER

2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER

Product Name
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
CAS No.
957198-30-0
Chemical Name
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
Synonyms
2-(Morpholino)pyrimidine-5-boronic acid pinacol ester;2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester;2-(4-Morphelino)pyrimidine-5-boronic acid pinacol ester;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol eser;9 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester;2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol ester 97%;2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;4-(5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidin-2-yl)Morpholine;2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER ISO 9001:2015 REACH
CBNumber
CB8233024
Molecular Formula
C14H22BN3O3
Formula Weight
291.15
MOL File
957198-30-0.mol
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2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Property

Density 
1.16
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BML00298
Product name
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
Purity
Aldrich
Packaging
1g
Price
$330
Updated
2025/07/31
TRC
Product number
M725233
Product name
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
M725233
Product name
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
Packaging
100mg
Price
$60
Updated
2021/12/16
Usbiological
Product number
281839
Product name
2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester
Packaging
500mg
Price
$496
Updated
2021/12/16
AK Scientific
Product number
AMTB1306
Product name
2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
Packaging
250mg
Price
$24
Updated
2021/12/16
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2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

84539-22-0

73183-34-3

957198-30-0

4-(5-bromopyrimidin-2-yl)morpholine (2.01 g, 8.23 mmol), pinacol ester of bis(boronic acid) (3.8 g, 15 mmol), potassium acetate (2.5 g, 25 mmol) and Pd(dppf)Cl2 (0.61 g, 0.83 mmol) were mixed in 1,4-dioxane (30 mL). The reaction mixture was stirred at 90 °C overnight under nitrogen protection. After completion of the reaction, the mixture was cooled to room temperature and diluted with water (20 mL). The reaction mixture was extracted with dichloromethane (30 mL x 3). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with petroleum ether/ethyl acetate (v/v = 7/3) as eluent to give a white solid product (0.4 g, 88% yield). m/z MS (ESI, cationic): 292.0 [M + 1]+.

References

[1] Patent: WO2016/615, 2016, A1. Location in patent: Paragraph 00730

2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER Suppliers

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View Lastest Price from 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 957198-30-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

957198-30-0, 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTERRelated Search:


  • 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
  • 2-(4-Morphelino)pyrimidine-5-boronic acid pinacol ester
  • 9 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester
  • 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
  • 2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester
  • 4-(5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidin-2-yl)Morpholine
  • 2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol eser
  • 2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol ester 97%
  • 2-(Morpholino)pyrimidine-5-boronic acid pinacol ester
  • Morpholine, 4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyrimidinyl]-
  • 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER ISO 9001:2015 REACH
  • 957198-30-0
  • C14H22BN3O3
  • Organoborons
  • Pyrimidine