P-XYLENOLPHTHALEIN

Product Name: P-XYLENOLPHTHALEIN
CAS No.: 50984-88-8
Chemical Name: P-XYLENOLPHTHALEIN
Synonyms: Xylenolphthalein;P-XYLENOLPHTHALEIN;P-xylenolphthaleine;p-diphenolphthalein;p-Xylenolphthalein;p-xylenolphthalein (pH 9.0-10.5);3,3-bis(4-hydroxy-2,5-xylyl)phthalide;2',5',2'',5''-TETRAMETHYLPHENOLPHTHALEIN;3,3-bis(4-hydroxy-2,5-dimethylphenyl)-2-benzofuran-1-one;P-xylenolphthalein, 2′,5′,2″,5″-tetramethylphenolphthalein
CBNumber: CB8233468
Molecular Formula: C24H22O4
Formula Weight: 374.43
MOL File: 50984-88-8.mol

More

Less

P-XYLENOLPHTHALEIN Property

Melting point:: 276°C
Boiling point:: 569.6±50.0 °C(Predicted)
Density: 1.270±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Solubility Insoluble in water; soluble in ethanol, acetone
pka: 9.7(at 25℃)
form: powder
color: Pale yellow or cream-colored
PH Range: Colorless (9.0) to indigo-blue (10.5)
BRN: 346799
Major Application: Inks, detergent, photoresist, toothpaste and mouthwash, disinfectant, cosmetics, paints
InChI: InChI=1S/C24H22O4/c1-13-11-21(25)15(3)9-19(13)24(20-10-16(4)22(26)12-14(20)2)18-8-6-5-7-17(18)23(27)28-24/h5-12,25-26H,1-4H3
InChIKey: PXCIPOXPHMTCIL-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC=C2)C(C2=CC(C)=C(O)C=C2C)(C2=CC(C)=C(O)C=C2C)O1

More

Less

Safety

WGK Germany: 3
HS Code: 2932.99.7000

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 95620
Product name: p-Xylenolphthalein
Purity: for microscopy
Packaging: 5g
Price: $468
Updated: 2022/05/15

TCI Chemical

Product number: X0017
Product name: p-Xylenolphthalein
Packaging: 1g
Price: $31
Updated: 2025/07/31

Matrix Scientific

Product number: 094350
Product name: 3,3-Bis(4-hydroxy-2,5-dimethylphenyl)-isobenzofuran-1(3H)-one
Purity: 95+%
Packaging: 1g
Price: $189
Updated: 2021/12/16

Matrix Scientific

Product number: 094350
Product name: 3,3-Bis(4-hydroxy-2,5-dimethylphenyl)-isobenzofuran-1(3H)-one
Purity: 95+%
Packaging: 5g
Price: $504
Updated: 2021/12/16

Matrix Scientific

Product number: 094350
Product name: 3,3-Bis(4-hydroxy-2,5-dimethylphenyl)-isobenzofuran-1(3H)-one
Purity: 95+%
Packaging: 10g
Price: $788
Updated: 2021/12/16

More

Less

P-XYLENOLPHTHALEIN Chemical Properties,Usage,Production

Uses

p-Xylenolphthalein is related to phenolphthalein which is used as a pH change indicator.

Synthesis

95-87-4

85-44-9

50984-88-8

General procedure for the synthesis of 3,3-bis-(4-hydroxy-3,6-dimethylphenyl)-1-(3H)-isobenzofuranone from 2,5-dimethylphenol and phthalic anhydride: a mixture of 2,5-dimethylphenol (0.133 mol), phthalic anhydride (0.074 mol), reaction medium (0.416 mol) and Lewis acid (0.029 mol ) were placed in a reaction flask, stirred and heated at 90 °C for 5 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature and subsequently slowly poured into an ice-water mixture to induce precipitation of the product. The precipitate was collected by filtration and washed with plenty of water to remove impurities. The crude product was dried and recrystallized from methanol to afford pure 3,3-bis-(4-hydroxy-3,6-dimethylphenyl)-1-(3H)-isobenzofuranone as light yellow crystals in 85% yield. The product was analyzed by IR (KBr) showing that the characteristic absorption peaks were located at 3393 cm^-1 (O-H stretching vibration), 1729 cm^-1 (C=O stretching vibration), and 1611 cm^-1 (C=C stretching vibration of the aromatic ring).The 1H-NMR (DMSO-d6) spectrum showed the following: δ 9.40 (s, 2H, 2×OH), 1.95 (s, 12H, 4 × CH3), 6.59-6.63 (m, 4H, aromatic protons), 7.46-7.91 (m, 4H, aromatic protons) ppm. mass spectrometry analysis showed the molecular ion peak m/z 374 (M+).

References

[1] Patent: US2006/222601, 2006, A1. Location in patent: Page/Page column 25
[2] Tetrahedron Letters, 2009, vol. 50, # 46, p. 6261 - 6263
[3] Zeitschrift fuer Anorganische und Allgemeine Chemie, 1929, vol. 178, p. 54,56
[4] Roczniki Chemii, 1931, vol. 11, p. 103,109; dtsch. Ref. S. 111
[5] Chem. Zentralbl., 1931, vol. 102, # I, p. 2473

P-XYLENOLPHTHALEIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

P-XYLENOLPHTHALEIN Suppliers

China 89 Germany 2 India 2 Japan 1 Switzerland 1 United Kingdom 3 United States 10 Global 108

Anhui Tianjia Chemical Science & Technology Co.,Ltd.

Tel: 0550-2392698 18355069969
Fax: 0550-2392698
Email: tianjiachem@hotmail.com
Country: China
ProdList: 18
Advantage: 57

Wuhan haorong Biotechnology Co., Ltd

Tel: 18186132299; 18186132299
Fax: 18186132299
Email: 489527785@qq.com
Country: China
ProdList: 521
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

More

Less

View Lastest Price from P-XYLENOLPHTHALEIN manufacturers

Career Henan Chemical Co

Product: P-XYLENOLPHTHALEIN 50984-88-8
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-08

50984-88-8, P-XYLENOLPHTHALEINRelated Search:

Thymolphthalein o-Cresolphthalein Complexone Methyl Orange o-Cresolphthalein alpha-Naphtholphthalein Phenolphthalein Thymolphthalein monophosphate magnesium salt THYMOL VIOLET THYMOLPHTHALEIN MONOPHOSPHATE DISODIUM SALT Thymolphthalein monophosphate 2-amino-2-methyl-1,3-propanediol salt Thymolphthalein Complexone Thymolphthalein complexone disodium salt P-XYLENOLPHTHALEIN Thymolphthalein phosphoric acid diammonium salt Thymolphthalein monophosphoric acid disodium salt trihydrate THYMOLPHTHALEIN MONOPHOSPHATE MAGNESIUM SALT THYMOLPHTHALEIN MONOPHOSPHORIC ACID, DI-2-AMINO-2-METHYL-1,3-PROPANEDIOL SALT PHENOLPHTHALEIN-THYMOLPHTHALEIN

P-XYLENOLPHTHALEIN

2',5',2'',5''-TETRAMETHYLPHENOLPHTHALEIN

3,3-Bis(2,5-dimethyl-4-hydroxyphenyl)isobenzofuran-1(3H)-one

3,3-Bis(4-hydroxy-2,5-dimethylphenyl)-1(3H)-isobenzofuranone

3,3-Bis(4-hydroxy-2,5-dimethylphenyl)isobenzofuran-1(3H)-one

4,4'-[(3-Oxo-1,3-dihydroisobenzofuran)-1,1-diyl]bis(2,5-dimethylphenol)

p-xylenolphthalein (pH 9.0-10.5)

P-xylenolphthaleine

3,3-bis(4-hydroxy-2,5-xylyl)phthalide

P-xylenolphthalein, 2′,5′,2″,5″-tetramethylphenolphthalein

Xylenolphthalein

3,3-bis(4-hydroxy-2,5-dimethylphenyl)-2-benzofuran-1-one

1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-2,5-dimethylphenyl)-

p-diphenolphthalein

<i>p</i>-Xylenolphthalein

50984-88-8

C24H22O4

Phthalein