o-Cresolphthalein
- Product Name
- o-Cresolphthalein
- CAS No.
- 596-27-0
- Chemical Name
- o-Cresolphthalein
- Synonyms
- cresolphthalein;o-Cresolphalein;o-Cresolphthalei;o-cresolphtaleine;O-CRESOLPHTHALEIN;O-Cresolphtnalein;Cresolphthanalein;3,3-Bis(4-hydroxy-;o-CRESOLPHTHLALEIN;TIMTEC-BB SBB006498
- CBNumber
- CB6392671
- Molecular Formula
- C22H18O4
- Formula Weight
- 346.38
- MOL File
- 596-27-0.mol
o-Cresolphthalein Property
- Melting point:
- 223-225 °C
- Boiling point:
- 401.12°C (rough estimate)
- Density
- 1.1425 (rough estimate)
- refractive index
- 1.4400 (estimate)
- solubility
- Solubility Slightly soluble in water; soluble in ethanol
- form
- powder
- pka
- 9.40(at 25℃)
- color
- Clear colorless
- PH Range
- 8.2 (colorless) - 9.8 (violet/red)
- Water Solubility
- slightly soluble
- λmax
- 566nm, 381nm
- Merck
- 14,2576
- BRN
- 310554
- Major Application
- Sensors, display device, photoresists, recording materials, imaging materials, authentication system for secure documents, decoder system, lithium cells, electroplating process, inks, markers, toners, correction fluid, paints, adhesives, floor coatings, gas leaking detector for safety in industries, toys, food storage, diapers, determination of calcium, lotions, urine analysis test strips, drugs, blood analysis
- InChIKey
- CPBJMKMKNCRKQB-UHFFFAOYSA-N
- CAS DataBase Reference
- 596-27-0(CAS DataBase Reference)
- EPA Substance Registry System
- 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- (596-27-0)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 40-36/37/38-20/21/22
- Safety Statements
- 36/37-36-26
- RIDADR
- 1170
- WGK Germany
- 3
- RTECS
- SM8390000
- TSCA
- Yes
- HS Code
- 3822.19.0080
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H340May cause genetic defects
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C85778
- Product name
- o-Cresolphthalein
- Purity
- indicator grade
- Packaging
- 10g
- Price
- $58.4
- Updated
- 2024/03/01
- Product number
- C0404
- Product name
- o-Cresolphthalein
- Packaging
- 25g
- Price
- $65
- Updated
- 2024/03/01
- Product number
- C0404
- Product name
- o-Cresolphthalein
- Packaging
- 100g
- Price
- $171
- Updated
- 2024/03/01
- Product number
- A12899
- Product name
- o-Cresolphthalein
- Packaging
- 10g
- Price
- $35.7
- Updated
- 2024/03/01
- Product number
- A12899
- Product name
- o-Cresolphthalein
- Packaging
- 50g
- Price
- $113
- Updated
- 2024/03/01
o-Cresolphthalein Chemical Properties,Usage,Production
Chemical Properties
white to pink or beige to tan powder. soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali and turns purple, slightly soluble in water, hardly soluble in benzene.
Uses
O-Cresolphthalein has been used as a component in calcifying media for calcification assay. It is also used as an indicator (pH range, 8.2 colorless, 9.8 red) and analytical reagent.
Application
O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.
Biochem/physiol Actions
o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.
o-Cresolphthalein Preparation Products And Raw materials
Raw materials
Preparation Products
o-Cresolphthalein Suppliers
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View Lastest Price from o-Cresolphthalein manufacturers
- Product
- o-Cresolphthalein 596-27-0
- Price
- US $18.50/Kg/Drum
- Min. Order
- 25KG
- Purity
- 95.0%
- Supply Ability
- 500kg per month
- Release date
- 2020-08-11
- Product
- o-Cresolphthalein 596-27-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 50000kg
- Release date
- 2023-08-11
- Product
- o-Cresolphthalein 596-27-0
- Price
- US $48.00/Kg/Drum
- Min. Order
- 25KG
- Purity
- 98%
- Supply Ability
- 1-10mt
- Release date
- 2021-06-02