2-Nitrobenzenesulfonamide
- Product Name
- 2-Nitrobenzenesulfonamide
- CAS No.
- 5455-59-4
- Chemical Name
- 2-Nitrobenzenesulfonamide
- Synonyms
- NSC 23381;NSC 629275;2-NITROPHENYLSULFAMIDE;2-Nitrobenzolsulfonamid;2-Nitro-benzenesulfomide;O-NITROBENZENESULFONAMIDE;2-Nitrobenaenesulfonamide;2-NITROBENZENESULFONAMIDE;2-NITROBENZENESULPHONAMIDE;2-NITROBENZENESULFONYLAMINE
- CBNumber
- CB8240167
- Molecular Formula
- C6H6N2O4S
- Formula Weight
- 202.19
- MOL File
- 5455-59-4.mol
2-Nitrobenzenesulfonamide Property
- Melting point:
- 190-192 °C (lit.)
- Boiling point:
- 418.8±47.0 °C(Predicted)
- Density
- 1.505 (estimate)
- refractive index
- 1.6490 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol (Slightly, Heated, Sonicated)
- form
- solid
- pka
- 9.24±0.60(Predicted)
- color
- Off-White to Brown
- Water Solubility
- Slightly soluble in water.
- BRN
- 2214215
- InChI
- InChI=1S/C6H6N2O4S/c7-13(11,12)6-4-2-1-3-5(6)8(9)10/h1-4H,(H2,7,11,12)
- InChIKey
- GNDKYAWHEKZHPJ-UHFFFAOYSA-N
- SMILES
- C1(S(N)(=O)=O)=CC=CC=C1[N+]([O-])=O
- CAS DataBase Reference
- 5455-59-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Nitrobenzenesulfonamide(5455-59-4)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 36/37/39-26-22-37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29350090
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 228907
- Product name
- 2-Nitrobenzenesulfonamide
- Purity
- 98%
- Packaging
- 5g
- Price
- $73.7
- Updated
- 2025/07/31
- Product number
- 228907
- Product name
- 2-Nitrobenzenesulfonamide
- Purity
- 98%
- Packaging
- 25g
- Price
- $115
- Updated
- 2025/07/31
- Product number
- N0705
- Product name
- 2-Nitrobenzenesulfonamide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $56
- Updated
- 2025/07/31
- Product number
- N0705
- Product name
- 2-Nitrobenzenesulfonamide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $165
- Updated
- 2025/07/31
- Product number
- N493545
- Product name
- 2-Nitro-benzenesulfonamide
- Packaging
- 5g
- Price
- $250
- Updated
- 2021/12/16
2-Nitrobenzenesulfonamide Chemical Properties,Usage,Production
Chemical Properties
yellow to light brown crystalline powder
Uses
2-Nitro-benzenesulfonamide is a carbonic anhydrase inhibitor.
Synthesis
1694-92-4
5455-59-4
The general procedure for the synthesis of 2-nitrobenzenesulfonamide from o-nitrobenzenesulfonyl chloride was as follows: 120.0 g of 2-nitrobenzenesulfonyl chloride (Compound 1, 0.78 mol) was dissolved in 280 mL of tetrahydrofuran (THF) with 360.0 g of ammonium acetate (4.7 mol), heated to reflux and stirred overnight. After completion of the reaction, the solid product was collected by filtration and processed by vacuum drying to afford 86.0 g of 2-nitrobenzenesulfonamide (compound 2) as a yellow solid in 80% yield.
References
[1] Journal of Organic Chemistry, 2018, vol. 83, # 16, p. 9088 - 9095
[2] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0023-0025
[3] Patent: JP2005/314398, 2005, A. Location in patent: Page/Page column 25
[4] Justus Liebigs Annalen der Chemie, 1875, vol. 177, p. 62
[5] Magnetic Resonance in Chemistry, 1987, vol. 25, p. 189 - 193
2-Nitrobenzenesulfonamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Nitrobenzenesulfonamide manufacturers
- Product
- 2-Nitrobenzenesulfonamide 5455-59-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2018-12-19