7-BROMOQUINOLIN-2(1H)-ONE
- Product Name
- 7-BROMOQUINOLIN-2(1H)-ONE
- CAS No.
- 99465-10-8
- Chemical Name
- 7-BROMOQUINOLIN-2(1H)-ONE
- Synonyms
- 7-broMoquinolin-2-ol;7-Bromo-2(1H)-quinolinone;7-BROMOQUINOLIN-2(1H)-ONE;7-BroMo-1H-quinolin-2-one;7-Bromo-2-hydroxyquinoline;2(1H)-Quinolinone, 7-broMo-;7-broMo-1,2-dihydroquinolin-2-one
- CBNumber
- CB82449870
- Molecular Formula
- C9H6BrNO
- Formula Weight
- 224.05
- MOL File
- 99465-10-8.mol
7-BROMOQUINOLIN-2(1H)-ONE Property
- Melting point:
- 270-272℃
- Boiling point:
- 375.4±42.0 °C(Predicted)
- Density
- 1.620
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 10.91±0.70(Predicted)
- Appearance
- Off-white to light brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B686953
- Product name
- 7-Bromo-1H-quinolin-2-one
- Packaging
- 250mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- Y4894
- Product name
- 7-Bromoquinolin-2(1H)-one
- Packaging
- 250mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- FB142575
- Product name
- 7-Bromoquinolin-2(1H)-one
- Packaging
- 250mg
- Price
- $52.5
- Updated
- 2021/12/16
- Product number
- FB142575
- Product name
- 7-Bromoquinolin-2(1H)-one
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FB142575
- Product name
- 7-Bromoquinolin-2(1H)-one
- Packaging
- 2g
- Price
- $273
- Updated
- 2021/12/16
7-BROMOQUINOLIN-2(1H)-ONE Chemical Properties,Usage,Production
Synthesis
99455-15-9
99465-10-8
The general procedure for the synthesis of 7-bromo-2-chloroquinolin-2(1H)-one from 7-bromo-2-chloroquinoline was as follows: 7-bromo-2-chloroquinoline (5.0 g, 20.6 mmol) was dissolved in a mixed solvent of 5 M aqueous hydrochloric acid (133 mL) and 1,4-dioxane (14 mL) with stirring and heated to reflux for 2 hours. After completion of the reaction, it was cooled to room temperature, the precipitate precipitated was collected by filtration and washed with deionized water to afford 7-bromoquinolin-2(1H)-one as a colorless solid (4.3 g, 93% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 11.80 (s, 1H), 7.91 (d, J=8.0 Hz, 1H), 7.63 (d, J=8.0 Hz, 1H), 7.48 (d, J=8.0 Hz, 1H), 7.34 (dd, J=8.0, 4.0 Hz, 1H), 6.53 (d, J= 4.0 Hz, 1H).
References
[1] Patent: US2015/210655, 2015, A1. Location in patent: Paragraph 0291
[2] Patent: US9522894, 2016, B2. Location in patent: Page/Page column 34
[3] Patent: WO2008/71961, 2008, A1. Location in patent: Page/Page column 103-104
[4] Patent: WO2006/134378, 2006, A1. Location in patent: Page/Page column 61-62
7-BROMOQUINOLIN-2(1H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-BROMOQUINOLIN-2(1H)-ONE manufacturers
- Product
- 7-BROMOQUINOLIN-2(1H)-ONE 99465-10-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25