7-BROMO-4-CHLOROQUINOLINE

Product Name: 7-BROMO-4-CHLOROQUINOLINE
CAS No.: 75090-52-7
Chemical Name: 7-BROMO-4-CHLOROQUINOLINE
Synonyms: BUTTPARK 89\09-07;4-Chloro-7-bromoquinoline;7-BROMO-4-CHLOROQUINOLINE;Quinoline, 7-bromo-4-chloro-;7-Bromo-4-chloroquinoline 98%;7-Bromo-4-chloro-1-azanaphthalene
CBNumber: CB9319394
Molecular Formula: C9H5BrClN
Formula Weight: 242.5
MOL File: 75090-52-7.mol

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7-BROMO-4-CHLOROQUINOLINE Property

Melting point:: 105-106 °C
Boiling point:: 314.6±22.0 °C(Predicted)
Density: 1.673±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 1.99±0.27(Predicted)
color: Beige
InChI: InChI=1S/C9H5BrClN/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChIKey: JJUTYYVZDKDLBC-UHFFFAOYSA-N
SMILES: N1C2C(=CC=C(Br)C=2)C(Cl)=CC=1

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Safety

Hazard Codes: T
Risk Statements: 25-41
Safety Statements: 26-39-45
RIDADR: 2811
WGK Germany: 3
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BBO000274
Product name: 7-Bromo-4-chloroquinoline
Purity: Aldrich
Packaging: 1g
Price: $216
Updated: 2025/07/31

TRC

Product number: B684818
Product name: 7-Bromo-4-chloroquinoline
Packaging: 2.5g
Price: $330
Updated: 2021/12/16

AK Scientific

Product number: W8258
Product name: 7-Bromo-4-chloroquinoline
Packaging: 5g
Price: $316
Updated: 2021/12/16

Matrix Scientific

Product number: 072607
Product name: 7-Bromo-4-chloroquinoline
Purity: 95+%
Packaging: 5g
Price: $357
Updated: 2021/12/16

Apolloscientific

Product number: OR43544
Product name: 7-Bromo-4-chloroquinoline
Purity: 98%
Packaging: 5g
Price: $376
Updated: 2021/12/16

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7-BROMO-4-CHLOROQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Synthesis

82121-06-0

75090-52-7

General procedure for the synthesis of 4-chloro-7-bromoquinoline from 4-hydroxy-7-bromoquinoline: Phosphorus oxychloride (106.76 g, 696.28 mmol) was added in batches to a solution of dioxane (660 mL) containing 4-hydroxy-7-bromoquinoline (60 g, 267.8 mmol) at 30 °C. The reaction mixture was stirred at 100 °C for 40 min before confirming that 4-hydroxy-7-bromoquinoline had been completely converted to 4-chloro-7-bromoquinoline by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, the reaction was quenched with water (200 mL) and subsequently extracted with ethyl acetate (200 mL x 2). The combined organic phases were washed with saturated sodium chloride solution (100 mL x 2) and dried with anhydrous sodium sulfate. After concentration under reduced pressure, the target compound 4-chloro-7-bromoquinoline (light yellow solid, 59 g, 81.77% yield) was obtained. It was analyzed by liquid chromatography-mass spectrometry (LC-MS, ESI), and the molecular ion peak m/z was 243.8 ([M+H]+).

References

[1] Patent: EP3293177, 2018, A1. Location in patent: Paragraph 0459; 0460
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 3236
[3] Journal of the American Chemical Society, 1946, vol. 68, p. 113,115
[4] Journal of Medicinal Chemistry, 1998, vol. 41, # 25, p. 4918 - 4926
[5] Patent: WO2018/34918, 2018, A1. Location in patent: Page/Page column 71

7-BROMO-4-CHLOROQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-BROMO-4-CHLOROQUINOLINE Suppliers

China 121 Germany 2 India 1 United Kingdom 3 United States 17 Global 144

Quzhou AMK BioTech Co., Ltd

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View Lastest Price from 7-BROMO-4-CHLOROQUINOLINE manufacturers

Career Henan Chemical Co

Product: 7-BROMO-4-CHLOROQUINOLINE 75090-52-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-19

75090-52-7, 7-BROMO-4-CHLOROQUINOLINERelated Search:

7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine 1H-INDAZOLE, 5-BROMO-3-(TRIFLUOROMETHYL)- 7-Bromo-4-methyl-1H-indazole 7-BroMo-4,4-diMethyl-1,2,3,4-tetrahydro-isoquinoline 7-BROMOQUINOLIN-2(1H)-ONE 7-BROMO-5H-PYRIDO[4,3-B]INDOLE 6-BROMO-4-CHLOROQUINOLINE,6-Bromo-4-chloroquinoline ,97% 2-bromo-6-chloroquinoline 4-BROMO-8-CHLOROQUINOLINE 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97,6-Bromo-2-chloroquinoline-4-carboxylic acid 6-BROMO-2-CHLORO-QUINOLINE 8-BROMO-4-CHLOROQUINOLINE METHYL 6-BROMO-4-CHLOROQUINOLINE-2-CARBOXYLATE METHYL 8-BROMO-4-CHLOROQUINOLINE-2-CARBOXYLATE 4-Bromo-5-chloroquinoline 3-BROMO-2-CHLOROQUINOLINE 2-BROMO-4-CHLOROQUINOLINE 6-BROMO-2-CHLOROQUINOLINE-4-CARBONYL CHLORIDE

BUTTPARK 89\09-07

7-BROMO-4-CHLOROQUINOLINE

4-Chloro-7-bromoquinoline

7-Bromo-4-chloro-1-azanaphthalene

7-Bromo-4-chloroquinoline 98%

Quinoline, 7-bromo-4-chloro-

75090-52-7

CHIRAL CHEMICALS