ChemicalBook > CAS DataBase List > 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER

Product Name
4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER
CAS No.
1049004-32-1
Chemical Name
4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER
Synonyms
ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylate;ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate;Bpin-Cyclohexene-COOEt;Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);1-Ethoxycarbonylcyclohex-3-ene-4-boronic acid pinacol ester;4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester;4-(ETHOXY(HYDROXY)BORYL)CYCLOHEX-3-ENECARBOXYLATE PINACOL ESTER;4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester 97%;Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cycl...;ethyl 4-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boryl)cyclohex-
CBNumber
CB82460101
Molecular Formula
C15H25BO4
Formula Weight
280.17
MOL File
1049004-32-1.mol
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4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER Property

Boiling point:
312.6±52.0 °C(Predicted)
Density 
1.03
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C15H25BO4/c1-6-18-13(17)11-7-9-12(10-8-11)16-19-14(2,3)15(4,5)20-16/h9,11H,6-8,10H2,1-5H3
InChIKey
ZREZDODZGZVRBD-UHFFFAOYSA-N
SMILES
C1(C(OCC)=O)CCC(B2OC(C)(C)C(C)(C)O2)=CC1
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Safety

HS Code 
2931900090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
E894945
Product name
4-(Ethoxycarbonyl)cyclohexene-1-boronicAcidPinacolEster
Packaging
50mg
Price
$55
Updated
2021/12/16
TRC
Product number
E894945
Product name
4-(Ethoxycarbonyl)cyclohexene-1-boronicAcidPinacolEster
Packaging
100mg
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-W006635
Product name
Ethyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate
Purity
>97.0%
Packaging
250mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR360085
Product name
4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester
Purity
96%
Packaging
100mg
Price
$104
Updated
2021/12/16
ChemScene
Product number
CS-W006635
Product name
Ethyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate
Purity
>97.0%
Packaging
1g
Price
$140
Updated
2021/12/16
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4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester

Synthesis

122948-57-6

73183-34-3

1049004-32-1

Ethyl 4-((trifluoromethanesulfonyl)oxy)-3-cyclohexene-1-carboxylate (303 mg, 1 mmol) and pinacol ester of bis(boronic acid) (370 mg, 1.5 mmol) were added to KOAc (400 mg, 4 mmol) and Pd(dppf)Cl2 (10 mg, 0.05 mmol) in dioxane (5 mL). The reaction mixture was heated at 110 °C for 16 hours. After completion of the reaction, it was cooled to room temperature and the mixture was partitioned between EtOAc (10 mL) and saturated NaHCO3 solution (10 mL). The aqueous phase was extracted with EtOAc (10 mL × 2). The combined organic phases were washed with brine, dried over anhydrous MgSO4, filtered, and concentrated. Purification by fast chromatography (25% EtOAc in petroleum ether solution) afforded ethyl 4-boronic acid pinacol ester-3-cyclohexenecarboxylate (250 mg, 89% yield).LRMS m/z (M + H)+: 281 (measured value), 281 (calculated value).

References

[1] Patent: WO2014/81619, 2014, A1. Location in patent: Page/Page column 128
[2] Patent: US2011/251183, 2011, A1. Location in patent: Page/Page column 18
[3] Patent: US2011/263578, 2011, A1. Location in patent: Page/Page column 34
[4] Patent: WO2011/128265, 2011, A1. Location in patent: Page/Page column 34
[5] Patent: US2011/275801, 2011, A1. Location in patent: Page/Page column 49

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER Suppliers

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View Lastest Price from 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co
Product
4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER 1049004-32-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-100%
Supply Ability
1
Release date
2018-08-10

1049004-32-1, 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTERRelated Search:

4-Chloro-3-methoxyphenylboronic acid pinacolester 2-[(3-chlorophenyl)Methyl]-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane (2-BROMOMETHYLPHENYL)BORONIC ACID, PINACOL ESTER 4-ISOXAZOLEBORONIC ACID PINACOL ESTER Ethyl 2-Methyl-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate methyl 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 2-(2,5-DibroMophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane 3-Methoxybenzylboronic acid pinacol ester

  • 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-Cyclohexene-1-carboxylic acid ethyl ester
  • ethyl 4-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boryl)cyclohex-3-enecarboxylate
  • Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)
  • 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)CYCLOHEX-3-ENE-1-CARBOXYLIC ACID ETHYL ESTER
  • 1-Ethoxycarbonylcyclohex-3-ene-4-boronic acid pinacol ester
  • ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate
  • 3-Cyclohexene-1-carboxylic acid, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester
  • 4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester
  • 4-(4,4,5,5-TetraMethyl-[1,3,2]dioxaborolan-2-yl)-cyclohex-3-enecarboxylic acid ethyl ester
  • 4-(ETHOXY(HYDROXY)BORYL)CYCLOHEX-3-ENECARBOXYLATE PINACOL ESTER
  • ethyl 4-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boryl)cyclohex-
  • ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylate
  • Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate
  • 4-(Ethoxycarbonyl)cyclohexene-1-boronic acid, pinacol ester 97%
  • Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cycl...
  • ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylateethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylate
  • Bpin-Cyclohexene-COOEt
  • Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate 97%min
  • 1049004-32-1