4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

Product Name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
CAS No.: 35808-68-5
Chemical Name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
Synonyms: NSC 344519;4-Chloro-6-Methyl-7H-pyrr...;4-chloro-6-methyl-1H-pyrrolo[2,3-d]pyrimidine;4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-;1H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-
CBNumber: CB82471237
Molecular Formula: C7H6ClN3
Formula Weight: 167.6
MOL File: 35808-68-5.mol

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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Property

Boiling point:: 292.2±50.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 11.49±0.40(Predicted)
Appearance: Off-white to light yellow Solid

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C384620
Product name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-D]pyrimidine
Packaging: 50mg
Price: $155
Updated: 2021/12/16

TRC

Product number: C384620
Product name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-D]pyrimidine
Packaging: 100mg
Price: $240
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-37
Product name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
Purity: 95%
Packaging: 1g
Price: $675
Updated: 2021/12/16

Matrix Scientific

Product number: 112374
Product name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
Packaging: 1g
Price: $1286
Updated: 2021/12/16

AK Scientific

Product number: W5733
Product name: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
Packaging: 10g
Price: $2028
Updated: 2021/12/16

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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production

Synthesis

252723-16-3

35808-68-5

Synthesis of compound 18.3. A mixture of potassium tert-butoxide (450 mg, 4 mmol) and 7-benzenesulfonyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (250 mg, 0.8 mmol) in tetrahydrofuran (7.5 mL) was stirred for 16 hours at room temperature. After completion of the reaction, saturated sodium bicarbonate solution was added to the reaction mixture. The reaction mixture was extracted with ethyl acetate (3 × 100 mL), the organic layers were combined, washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was purified by fast column chromatography with petroleum ether/ethyl acetate (100/0 to 0/100, v/v) as eluent to afford 4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (Compound 18.3, 118 mg, 87% yield).1H NMR (200 MHz, DMSO-d6) δ 12.5 (br s, 1H) 8.47 (s, 1H), 6.29 (s, 1H), 2.42 (s, 3H). Mass spectrum (MS) m/z 168 [M + H]+.

References

[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 26
[2] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 1103 - 1110
[3] Patent: WO2012/158795, 2012, A1. Location in patent: Page/Page column 102
[4] Patent: WO2012/158764, 2012, A1. Location in patent: Page/Page column 215-216
[5] Patent: WO2013/191965, 2013, A1. Location in patent: Page/Page column 191

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Suppliers

China 89 India 1 United Kingdom 1 United States 7 Global 98

Pure Chemistry Scientific Inc.

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Wuhan Kaymke Chemical Co., Ltd.,

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View Lastest Price from 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 35808-68-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-15

Career Henan Chemical Co

Product: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 35808-68-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-02

35808-68-5, 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidineRelated Search:

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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

4-chloro-6-methyl-1H-pyrrolo[2,3-d]pyrimidine

NSC 344519

1H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-

4-Chloro-6-Methyl-7H-pyrr...

7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-

35808-68-5

Heterocycle-Pyrimidine series