(1R,2R)-1,2-Cyclohexanedimethanol

Product Name: (1R,2R)-1,2-Cyclohexanedimethanol
CAS No.: 65376-05-8
Chemical Name: (1R,2R)-1,2-Cyclohexanedimethanol
Synonyms: [(1R,2R)-2-(hydroxymethyl)cyclohexyl]methanol;Lurasidone KSM / (1R,2R)-1,2-;(1R,2R)-cyclohexane-1,2-diyldimethanol;(1R,2R)-1,2-Bis(hydroxymethyl)cyclohexane;Lurasidone INT 3;(1R,2R)-1,2-CYCLOHEXANEDI;Lurasidone HCL Intermediates;(R,R)-Cyclohexane-1,2-dimethanol;(1R,2R)-1,2-CYCLOHEXANEDIMETHANO;(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL
CBNumber: CB82474687
Molecular Formula: C8H16O2
Formula Weight: 144.21
MOL File: 65376-05-8.mol

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(1R,2R)-1,2-Cyclohexanedimethanol Property

Melting point:: 63.0 to 67.0 °C
Boiling point:: 270℃
Density: 1.004
Flash point:: 129℃
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.75±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C8H16O2/c9-5-7-3-1-2-4-8(7)6-10/h7-10H,1-6H2/t7-,8-/m0/s1
InChIKey: XDODWINGEHBYRT-YUMQZZPRSA-N
SMILES: [C@@H]1(CO)CCCC[C@H]1CO

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Safety

HS Code: 2906.19.5000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2978
Product name: (1R,2R)-1,2-Cyclohexanedimethanol
Purity: >98.0%(GC)
Packaging: 1g
Price: $127
Updated: 2025/07/31

TCI Chemical

Product number: C2978
Product name: (1R,2R)-1,2-Cyclohexanedimethanol
Purity: >98.0%(GC)
Packaging: 5g
Price: $382
Updated: 2025/07/31

TRC

Product number: C987945
Product name: (1R,2R)-1,2-Cyclohexanedimethanol
Packaging: 250mg
Price: $1355
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20697
Product name: (1R,2R)-1,2-Cyclohexanedimethanol
Packaging: 250mg
Price: $1530
Updated: 2021/12/16

ChemScene

Product number: CS-0028229
Product name: (1R,2R)-Cyclohexane-1,2-diyldimethanol
Purity: 99.99%
Packaging: 25g
Price: $105
Updated: 2021/12/16

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(1R,2R)-1,2-Cyclohexanedimethanol Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

(1R,2R)-1,2-Cyclohexanedimethanol (cas# 65376-05-8) is a compound useful in organic synthesis.

Synthesis

46022-05-3

65376-05-8

General procedure for the synthesis of (1R,2R)-1,2-cyclohexanedicarboxylic acid as a raw material for the synthesis of (1R,2R)-1,2-cyclohexanedimethanol: A mixture of (1R,2R)-1,2-cyclohexanedicarboxylic acid (248 g, 1.41 mol), sodium borohydride (159.8 g, 4.2 mol), and iodine (156 g, 0.7 mol) was added to tetrahydrofuran ( THF, 1000 mL), stirred, and reacted at reflux for 5 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C and methanol (500 mL) was added slowly and dropwise. The organic layer was separated, dried with anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure and dried to give the white solid product (1R,2R)-1,2-cyclohexanedimethanol (178 g, 1.709 mol, 88.4% yield) with a melting point of 57-59 °C.

References

[1] Patent: CN105732644, 2016, A. Location in patent: Paragraph 0006; 0007
[2] Synthetic Communications, 2015, vol. 45, # 23, p. 2676 - 2682
[3] Tetrahedron, 1965, vol. 21, p. 1701 - 1709
[4] Patent: WO2013/121440, 2013, A1. Location in patent: Page/Page column 27
[5] Patent: WO2016/59649, 2016, A1. Location in patent: Paragraph 20

(1R,2R)-1,2-Cyclohexanedimethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(1R,2R)-1,2-Cyclohexanedimethanol Suppliers

Americas 1 Canada 2 China 314 Europe 1 Germany 1 India 35 Japan 1 United Kingdom 6 United States 16 Global 377

Jiangxi Jinfeng Pharmaceutical Co., Ltd

Tel: 793-5181188 18170363299
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Jinan zhongdaoanran chemical Co;Ltd

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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Chemvon Biotechnology Co., Ltd

Tel: 021-50790412
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View Lastest Price from (1R,2R)-1,2-Cyclohexanedimethanol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: (1R,2R)-1,2-CYCLOHEXANEDIMETHANOL 65376-05-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Jinan Million Pharmaceutical Co., Ltd

Product: (1R,2R)-1,2-CYCLOHEXANEDIMETHANOL 65376-05-8
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1200KG/M
Release date: 2023-08-15

Henan Aochuang Chemical Co.,Ltd.

Product: (1R,2R)-1,2-CYCLOHEXANEDIMETHANOL 65376-05-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

65376-05-8, (1R,2R)-1,2-Cyclohexanedimethanol Related Search:

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(1R,2R)-1,2-CYCLOHEXANEDI

(1<i>R</i>,2<i>R</i>)-1,2-Cyclohexanedimethanol

(1R,2R)-cyclohexane-1,2-diyldimethanol

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(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL

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(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL in stock Factory

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Lurasidone KSM / (1R,2R)-1,2-

1,2-Cyclohexanedimethanol, (1R-trans)-

(1R,2R)-1,2-Cyclohexanedimethanol(For export only)

(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL ISO 9001：2015 REACH

(R,R)-Cyclohexane-1,2-dimethanol

RSSYY(Perospirone Hydrochloride Hydrate)-10

(+)-(1R,2R)-1,2-cyclohexanedimethanol

(1R,2R)-1,2-CYCLOHEXANEDIMETHANO

Lurasidone HCL Intermediates

(1R,2R)Cyclohexan-1,2-diyldimethanol

65376-05-8

Miscellaneous Reagents