Sodium Phosphate, Dibasic
- Product Name
- Sodium Phosphate, Dibasic
- CAS No.
- 7558-79-4
- Chemical Name
- Sodium Phosphate, Dibasic
- Synonyms
- DISODIUM PHOSPHATE;DSP;DISODIUM HYDROGEN PHOSPHATE;DIBASIC SODIUM PHOSPHATE;DSPA;DISODIUM PHOSPHATE DIHYDRATE;BUFFER SOLUTION;Sodium phosphate dibasic anhydrous;SODIUM HYDROGENPHOSPHATE;SODIUM MONOHYDROGEN PHOSPHATE
- CBNumber
- CB1242667
- Molecular Formula
- Na2HPO4
- Formula Weight
- 141.96
- MOL File
- 7558-79-4.mol
Sodium Phosphate, Dibasic Property
- Melting point:
- 243-245 °C
- Density
- 1.064 g/mL at 20 °C
- vapor density
- 4.9 (vs air)
- vapor pressure
- 0Pa at 20℃
- FEMA
- 2398 | DISODIUM PHOSPHATE
- storage temp.
- Store at +5°C to +30°C.
- solubility
- H2O: 0.5 M at 20 °C, clear, colorless
- form
- powder
- color
- White
- PH
- 8.9-9.2 (25℃, 50g/L in water)
- pka
- (1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
- Odor
- odorless
- Water Solubility
- >=10 g/100 mL at 20 ºC
- Sensitive
- Hygroscopic
- λmax
- λ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016 - Merck
- 14,8659
- Stability:
- Stable. Incompatible with strong acids. Hygroscopic.
- InChIKey
- BNIILDVGGAEEIG-UHFFFAOYSA-L
- LogP
- -2.15
- CAS DataBase Reference
- 7558-79-4(CAS DataBase Reference)
- EPA Substance Registry System
- Disodium phosphate (7558-79-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- RTECS
- WC4500000
- F
- 3
- TSCA
- Yes
- HS Code
- 28352200
- Hazardous Substances Data
- 7558-79-4(Hazardous Substances Data)
- Toxicity
- LD50 orally in Rabbit: > 2000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 94046
- Product name
- Sodium phosphate dibasic solution
- Purity
- BioUltra, 0.5?M in H2O
- Packaging
- 100mL
- Price
- $64.9
- Updated
- 2024/03/01
- Product number
- NIST2186II
- Product name
- Disodium hydrogen phosphate
- Purity
- NISTSRM2186II
- Packaging
- 30g
- Price
- $947
- Updated
- 2024/03/01
- Product number
- 94046
- Product name
- Sodium phosphate dibasic solution
- Purity
- BioUltra, 0.5?M in H2O
- Packaging
- 500mL
- Price
- $196
- Updated
- 2024/03/01
- Product number
- 567550
- Product name
- Sodium Phosphate, Dibasic - CAS 7558-79-4 - Calbiochem
- Purity
- ACS Reagent Grade. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
- Packaging
- 500g
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 567547
- Product name
- Sodium Phosphate, Dibasic, Molecular Biology Grade - CAS 7558-79-4 - Calbiochem
- Purity
- Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
- Packaging
- 250g
- Price
- $63.3
- Updated
- 2024/03/01
Sodium Phosphate, Dibasic Chemical Properties,Usage,Production
Description
Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.
Chemical Properties
Disodium phosphate is anhydrous or contains two molecules of water of hydration
Chemical Properties
Sodium hydrogen phosphate,NaH2P04·H20, is hygroscopic, transparent, water-soluble crystals. Used as a purgative, reagent,and buffer.
Chemical Properties
The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.
Physical properties
The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.
Occurrence
Disodium phosphate is anhydrous or contains two molecules of water of hydration
Uses
Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.
Uses
It is used in pH buffer solutions.
Uses
Sodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.
Definition
ChEBI: Disodium hydrogenphosphate is a sodium phosphate.
Preparation
Dibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4
General Description
Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.
Safety Profile
Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.
Purification Methods
Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.
Sodium Phosphate, Dibasic Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sodium Phosphate, Dibasic manufacturers
- Product
- Disodium Phosphate 7558-79-4
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-08
- Product
- Sodium Phosphate 7558-79-4
- Price
- US $3.60/kg
- Min. Order
- 1kg
- Purity
- ≥99%
- Supply Ability
- 3000tons/month
- Release date
- 2024-07-30
- Product
- Sodium Phosphate, Dibasic 7558-79-4
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-06