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Sodium Phosphate, Dibasic

Product Name
Sodium Phosphate, Dibasic
CAS No.
7558-79-4
Chemical Name
Sodium Phosphate, Dibasic
Synonyms
DISODIUM PHOSPHATE;DSP;DISODIUM HYDROGEN PHOSPHATE;DIBASIC SODIUM PHOSPHATE;DSPA;DISODIUM PHOSPHATE DIHYDRATE;BUFFER SOLUTION;Sodium phosphate dibasic anhydrous;SODIUM HYDROGENPHOSPHATE;SODIUM MONOHYDROGEN PHOSPHATE
CBNumber
CB1242667
Molecular Formula
Na2HPO4
Formula Weight
141.96
MOL File
7558-79-4.mol
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Sodium Phosphate, Dibasic Property

Melting point:
243-245 °C
Density 
1.064 g/mL at 20 °C
vapor density 
4.9 (vs air)
vapor pressure 
0Pa at 20℃
FEMA 
2398 | DISODIUM PHOSPHATE
storage temp. 
Store at +5°C to +30°C.
solubility 
H2O: 0.5 M at 20 °C, clear, colorless
form 
powder
color 
White
PH
8.9-9.2 (25℃, 50g/L in water)
pka
(1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odor
odorless
Water Solubility 
>=10 g/100 mL at 20 ºC
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016
Merck 
14,8659
Stability:
Stable. Incompatible with strong acids. Hygroscopic.
InChIKey
BNIILDVGGAEEIG-UHFFFAOYSA-L
LogP
-2.15
CAS DataBase Reference
7558-79-4(CAS DataBase Reference)
EPA Substance Registry System
Disodium phosphate (7558-79-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
WC4500000
3
TSCA 
Yes
HS Code 
28352200
Hazardous Substances Data
7558-79-4(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
94046
Product name
Sodium phosphate dibasic solution
Purity
BioUltra, 0.5?M in H2O
Packaging
100mL
Price
$64.9
Updated
2024/03/01
Sigma-Aldrich
Product number
NIST2186II
Product name
Disodium hydrogen phosphate
Purity
NISTSRM2186II
Packaging
30g
Price
$947
Updated
2024/03/01
Sigma-Aldrich
Product number
94046
Product name
Sodium phosphate dibasic solution
Purity
BioUltra, 0.5?M in H2O
Packaging
500mL
Price
$196
Updated
2024/03/01
Sigma-Aldrich
Product number
567550
Product name
Sodium Phosphate, Dibasic - CAS 7558-79-4 - Calbiochem
Purity
ACS Reagent Grade. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
Packaging
500g
Price
$97
Updated
2024/03/01
Sigma-Aldrich
Product number
567547
Product name
Sodium Phosphate, Dibasic, Molecular Biology Grade - CAS 7558-79-4 - Calbiochem
Purity
Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
Packaging
250g
Price
$63.3
Updated
2024/03/01
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Sodium Phosphate, Dibasic Chemical Properties,Usage,Production

Description

Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Chemical Properties

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Chemical Properties

Sodium hydrogen phosphate,NaH2P04·H20, is hygroscopic, transparent, water-soluble crystals. Used as a purgative, reagent,and buffer.

Chemical Properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.

Physical properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.

Occurrence

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Uses

Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Uses

It is used in pH buffer solutions.

Uses

Sodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.

Definition

ChEBI: Disodium hydrogenphosphate is a sodium phosphate.

Preparation

Dibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4

General Description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.

Purification Methods

Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.

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Sodium Phosphate, Dibasic Suppliers

Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
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China
ProdList
24842
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Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
21450
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Lianyungang Kexin Chemical Co., Ltd.
Tel
518-+86-188051 +86-18805133257
Fax
051885110578
Email
sales3257@jskolod.com
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China
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Guangzhou Yunmen Biotechnology Co., Ltd
Tel
18902340307 18902340307
Fax
0751-2819901
Email
3356812514@qq.com
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China
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Watson Biotechnology Co.,Ltd
Tel
027-027-59207879 18140587686
Fax
QQ:1972026995
Email
kf@3600chem.com
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China
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Shanghai hongrui chemical co., ltd
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13906273813 13485185589
Email
834955168@qq.com
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China
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Yonghua Chemical Co., Ltd.
Tel
0512-52549999-873 13706235395
Fax
+86-52546337
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2851087488@qq.com
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China
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Hubei Taihechang Biotechnology Co., Ltd
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18607169902 18607169902
Email
18607169902@163.com
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China
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
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market03@meryer.com
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China
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View Lastest Price from Sodium Phosphate, Dibasic manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Sodium Phosphate, Dibasic 7558-79-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-20
Hebei Jingbo New Material Technology Co., Ltd
Product
Sodium Phosphate, Dibasic 7558-79-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000000
Release date
2023-12-12
Henan Fengda Chemical Co., Ltd
Product
Sodium Phosphate, Dibasic 7558-79-4
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22

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