Sodium Phosphate, Dibasic

Product Name: Sodium Phosphate, Dibasic
CAS No.: 7558-79-4
Chemical Name: Sodium Phosphate, Dibasic
Synonyms: DISODIUM PHOSPHATE;DSP;DISODIUM HYDROGEN PHOSPHATE;DIBASIC SODIUM PHOSPHATE;DSPA;DISODIUM PHOSPHATE DIHYDRATE;BUFFER SOLUTION;Sodium phosphate dibasic anhydrous;SODIUM HYDROGENPHOSPHATE;SODIUM MONOHYDROGEN PHOSPHATE
CBNumber: CB1242667
Molecular Formula: Na2HPO4
Formula Weight: 141.96
MOL File: 7558-79-4.mol

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Sodium Phosphate, Dibasic Property

Melting point:: 243-245 °C
Density: 1.064 g/mL at 20 °C
vapor density: 4.9 (vs air)
vapor pressure: 0Pa at 20℃
FEMA: 2398 | DISODIUM PHOSPHATE
storage temp.: Store at +5°C to +30°C.
solubility: H₂O: 0.5 M at 20 °C, clear, colorless
form: powder
color: White
PH: 8.9-9.2 (25℃, 50g/L in water)
pka: (1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odor: odorless
Water Solubility: >=10 g/100 mL at 20 ºC
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016
Merck: 14,8659
Stability:: Stable. Incompatible with strong acids. Hygroscopic.
InChIKey: BNIILDVGGAEEIG-UHFFFAOYSA-L
LogP: -2.15
CAS DataBase Reference: 7558-79-4(CAS DataBase Reference)
EPA Substance Registry System: Disodium phosphate (7558-79-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS: WC4500000
F: 3
TSCA: Yes
HS Code: 28352200
Hazardous Substances Data: 7558-79-4(Hazardous Substances Data)
Toxicity: LD50 orally in Rabbit: > 2000 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 94046
Product name: Sodium phosphate dibasic solution
Purity: BioUltra, 0.5?M in H2O
Packaging: 100mL
Price: $64.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: NIST2186II
Product name: Disodium hydrogen phosphate
Purity: NISTSRM2186II
Packaging: 30g
Price: $947
Updated: 2024/03/01

Sigma-Aldrich

Product number: 94046
Product name: Sodium phosphate dibasic solution
Purity: BioUltra, 0.5?M in H2O
Packaging: 500mL
Price: $196
Updated: 2024/03/01

Sigma-Aldrich

Product number: 567550
Product name: Sodium Phosphate, Dibasic - CAS 7558-79-4 - Calbiochem
Purity: ACS Reagent Grade. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
Packaging: 500g
Price: $97
Updated: 2024/03/01

Sigma-Aldrich

Product number: 567547
Product name: Sodium Phosphate, Dibasic, Molecular Biology Grade - CAS 7558-79-4 - Calbiochem
Purity: Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.
Packaging: 250g
Price: $63.3
Updated: 2024/03/01

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Sodium Phosphate, Dibasic Chemical Properties,Usage,Production

Description

Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Chemical Properties

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Chemical Properties

Sodium hydrogen phosphate,NaH2P04·H20, is hygroscopic, transparent, water-soluble crystals. Used as a purgative, reagent,and buffer.

Chemical Properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.

Physical properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm³; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm³ at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm³; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm³; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.

Occurrence

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Uses

Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Uses

It is used in pH buffer solutions.

Uses

Sodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.

Definition

ChEBI: Disodium hydrogenphosphate is a sodium phosphate.

Preparation

Dibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4

General Description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.

Purification Methods

Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.

Sodium Phosphate, Dibasic Preparation Products And Raw materials

Raw materials

Sodium phosphate dibasic dodecahydrate N-(Isoxazol-5-yl)sulphanilamide Phosphoric acid Sodium hydroxide White phosphorus Phosphorus Sulfuric acid Sodium carbonate

Preparation Products

Tartrazine Sodium phosphite ribonucleic acid for injection Penetrating agent 5881D Pigment Fast Rose Toner a new super water absorbent resin 1,2-EPOXYCYCLODODECANE Fosfomycin Flour improver Diethyl malonate

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Sodium Phosphate, Dibasic Suppliers

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View Lastest Price from Sodium Phosphate, Dibasic manufacturers

Hebei Andu Technology Com.,Ltd

Product: Sodium Phosphate 7558-79-4
Price: US $3.60/kg
Min. Order: 1kg
Purity: ≥99%
Supply Ability: 3000tons/month
Release date: 2024-07-30

Shaanxi Dideu Medichem Co. Ltd

Product: Sodium Phosphate, Dibasic 7558-79-4
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50ton
Release date: 2020-05-20

Hebei Longbang Technology Co., Ltd

Product: Sodium Phosphate, Dibasic 7558-79-4
Price: US $6.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20TONS
Release date: 2024-05-15

7558-79-4, Sodium Phosphate, DibasicRelated Search:

Trisodium phosphate Potassium Phosphate Monobasic FERRIC PHOSPHATE Sodium Phosphate Monobasic Monohydrate Hydrogen Calcium phosphate Ethylenediaminetetraacetic acid disodium salt Ammonium dihydrogen phosphate Zinc phosphate Creatine phosphate Sodium phosphate monobasic Sodium Monofluorophosphate Ammonium phosphate dibasic Potassium Phosphate Dibasic Potassium phosphate tribasic CERIUM(III) CHLORIDE Calcium silicate Calcium chloride Dibasic Sodium Phosphate Sodium Hydrogenphosphate Sodium Phosphate Dibasic Anhydrous

SODIUM PHOSPHATE, DIBASIC ANHYDROUS, TECHNICAL

SODIUM PHOSPHATE, DIBASIC BIO-REFINED

Sodiumhydrogenphosphate,99+%(ACS)

buffer solution from di-sodium hydrogen phosphate

sodium hydrogen phosphate, anhydrous, acs

sodium phosphate dibasic solution

DIBASICSODIUMPHOSPHATE,DRIED,USP

SODIUMPHOSPHATE,DIBASIC,ANHYDROUS,BIOTECHGRADE

SODIUMPHOSPHATE,DIBASIC,ANHYDROUS,FCC

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DISODIUMMONOPHOSPHATE

DINATRIUMHYDROGENPHOSPHATE

SODIUM HYDROGEN PHOSPHATE (ACS)

DI-SODIUM HYDROGEN PHOSPHATE ANHYDROUS USP, BP, PH EUR

DI-SODIUM HYDROGEN PHOSPHATE R. G., BUFF ER SUBSTANCE, REAG. ACS

SODIUM PHOSPHATE DIBASIC ANHYDROUS POWDER FCC

SODIUM PHOSPHATE DIBASIC DRIED POWDER USP/NF

Sodium phophate, dibasic

CREATINE ESTER SODIUM PHOSPHATE

Disodium hydrogen phosphate, anhydrous, 98+%

"Sodium hydrogen phosphate, anhydrous/ 98+%"

"Sodium hydrogen phosphate, anhydrous/ 99+%/ ACS"

EMPROVE(R) di-SodiuM Hydrogen Phosphate, Anhydrous, USP, BP, Ph Eur

SodiuM Phosphate Dibasic, Dried, USP, EP

SodiuM Phosphate Dibasic, Reagent, ACS

ADSP

SodiuM phosphate, dibasic, anhydrous, for analysis, 99+% 100GR

SodiuM phosphate, dibasic, anhydrous, for analysis, 99+% 500GR

SodiuM phosphate, dibasic, suitable for buffer solutions, for analysis ACS, 99+% 500GR

DIBASIC SODIUM PHOSPHATE

DINATRII PHOSPHAS DIHYDRICUS

DINATRII PHOSPHAS ANHYDRICUS

DISODIUM PHOSHATE

DISODIUM PHOSPHATE DIHYDRATE

DISODIUM PHOSPHATE

DI-SODIUM HYDROGEN ORTHOPHOSPHATE

DI-SODIUM HYDROGEN ORTHOPHOSPHATE 2H2O

acetest

disodiumacidorthophosphate

disodiumacidphosphate

di-Sodiumhydrogenphosphate,a

disodiumhydrophosphate

disodiumorthophosphate

disodiumphosphate,anhydrous

disodiumphosphoricacid

exsiccatedsodiumphosphate

femanumber2398.

natriumphosphat

orthophosphatedisodique

phosphateofsoda

sodaphosphate

sodiummonohydrogenorthophosphate

sodiummonohydrogenphosphate(2:1:1)

sodiumorthophosphate,secondary

sodiumphosphate(na2hpo4)

sodiumphosphatedibasic(sodium

sodiumphosphatedibasic(sodiumhydrogenphosphate)