3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Product Name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- CAS No.
- 1138443-83-0
- Chemical Name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Synonyms
- 3-Iodo-5-Methyl-7-azaindole ;3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine;1H-pyrrolo[2,3-b]pyridine, 3-iodo-5-Methyl-
- CBNumber
- CB82478625
- Molecular Formula
- C8H7IN2
- Formula Weight
- 258.06
- MOL File
- 1138443-83-0.mol
3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine Property
- Density
- 1.933
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 12.56±0.40(Predicted)
- Appearance
- Off-white to yellow Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- ADE000940
- Product name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $817
- Updated
- 2025/07/31
- Product number
- B449133
- Product name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 035134
- Product name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 250mg
- Price
- $149
- Updated
- 2021/12/16
- Product number
- CS-0041378
- Product name
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 250mg
- Price
- $187
- Updated
- 2021/12/16
- Product number
- LIP0000127
- Product name
- 3-IODO-5-METHYL-1H-PYRROLO[2,3-B]PYRIDINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $941.33
- Updated
- 2021/12/16
3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Usage,Production
Synthesis
918523-66-7
1138443-83-0
5-Methyl-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine (8, 1 g, 2.0 mmol) was used as a starting material and dissolved in 10 mL of tetrahydrofuran. In another vessel, iodine (0.43 g, 1.7 mmol) was dissolved in 5 mL of tetrahydrofuran, which was subsequently added to the tetrahydrofuran solution of the starting material. The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the reaction was quenched with 20 mL of aqueous 1 M sodium thiosulfate, followed by extraction with ethyl acetate. The organic layers were combined, washed sequentially with water and brine, and then dried over anhydrous sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated under vacuum. The resulting crude product was purified by silica gel column chromatography using ethyl acetate and hexane as eluents. The grades containing the target product were collected, combined and concentrated under vacuum to afford 3-iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine (10, 20 mg) as a white solid. The mass spectrum (ESI) showed [M + H]+ = 258.70.
References
[1] Patent: US2011/263595, 2011, A1. Location in patent: Page/Page column 78-79
[2] Patent: US9096593, 2015, B2. Location in patent: Page/Page column 90; 91
3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine Suppliers
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- Country
- India
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View Lastest Price from 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine manufacturers
- Product
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine 1138443-83-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 200g
- Release date
- 2020-02-01