4-BROMO-2-IODOANILINE
- Product Name
- 4-BROMO-2-IODOANILINE
- CAS No.
- 66416-72-6
- Chemical Name
- 4-BROMO-2-IODOANILINE
- Synonyms
- AKOS BB-7878;ASISCHEM T54343;4-BROMO-2-IODOANILINE;2-Iodine-4-bromoaniline;4-Bromo-2-iodoaNAine, 97%;4-Bromo-2-iodoaniline >4-Bromo-2-iodoaniline,97%;4-Bromo-2-iodoaniline 97%;4-BROMO-2-IODO-PHENYLAMINE;4-bromo-2-iodo-benzenamine
- CBNumber
- CB8248299
- Molecular Formula
- C6H5BrIN
- Formula Weight
- 297.92
- MOL File
- 66416-72-6.mol
4-BROMO-2-IODOANILINE Property
- Melting point:
- 69-72 °C(lit.)
- Boiling point:
- 297.9±30.0 °C(Predicted)
- Density
- 2.292±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- soluble in Methanol
- pka
- 1.83±0.10(Predicted)
- form
- Powder
- color
- Gray to purple
- InChI
- InChI=1S/C6H5BrIN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
- InChIKey
- HHTYEQWCHQEJNV-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(Br)C=C1I
- CAS DataBase Reference
- 66416-72-6(CAS DataBase Reference)
Safety
- Hazard Codes
- T,N,Xi
- Risk Statements
- 25-37/38-41-51/53
- Safety Statements
- 26-36/37/39-45-61
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 523267
- Product name
- 4-Bromo-2-iodoaniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $71.06
- Updated
- 2025/07/31
- Product number
- B3164
- Product name
- 4-Bromo-2-iodoaniline
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $22
- Updated
- 2025/07/31
- Product number
- B3164
- Product name
- 4-Bromo-2-iodoaniline
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $64
- Updated
- 2025/07/31
- Product number
- B687523
- Product name
- 4-Bromo-2-iodoaniline
- Packaging
- 10g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FB70320
- Product name
- 4-Bromo-2-iodoaniline
- Packaging
- 25g
- Price
- $70
- Updated
- 2021/12/16
4-BROMO-2-IODOANILINE Chemical Properties,Usage,Production
Chemical Properties
Grey to purple powder
Uses
4-Bromo-2-iodoaniline may be used in the following:
- Preparation of quinolone derivatives.
- Synthesis of a resin-bound sulfonamide, which was used as a starting material for the preparation of 2,3,5-trisubstituted indoles.
General Description
4-Bromo-2-iodoaniline is a 2-iodoaniline derivative. It can be prepared by reacting 4-bromoaniline with iodine.
Synthesis
106-40-1
66416-72-6
General procedure: Iodination of aryl amines was carried out under solvent-free conditions. DBDABCODCI (0.5 mmol) was co-milled with 4-bromoaniline (1 mmol) in a porcelain mortar at room temperature. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, ethyl acetate was added to the mixture and subsequently filtered. The organic layer was washed with 5% aqueous sodium thiosulfate and dried with anhydrous magnesium sulfate. The solvent was removed under reduced pressure and the resulting crude product was purified by column chromatography, the eluent being a solvent mixture of ethyl acetate and hexane. The purified product was characterized by melting point determination and 1H NMR spectroscopy.
References
[1] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 2, p. 600 - 602
[2] Bulletin of the Chemical Society of Ethiopia, 2015, vol. 29, # 1, p. 157 - 162
[3] RSC Advances, 2018, vol. 8, # 54, p. 30761 - 30776
[4] Synthesis, 2008, # 13, p. 2039 - 2044
[5] Patent: US9212182, 2015, B2. Location in patent: Page/Page column 198; 199
4-BROMO-2-IODOANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-BROMO-2-IODOANILINE Suppliers
- Tel
- 0371-63336364 17344886665
- Fax
- 0371-65511872
- 209932355@qq.com
- Country
- China
- ProdList
- 489
- Advantage
- 55
- Tel
- 18839185240
- 2148319152@qq.com
- Country
- China
- ProdList
- 428
- Advantage
- 58
- Tel
- 18602598900，18605190599 18602598900
- 1669093670@qq.com
- Country
- China
- ProdList
- 94
- Advantage
- 58
- Tel
- 15855184105
- 3150278607@qq.com
- Country
- China
- ProdList
- 63
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
View Lastest Price from 4-BROMO-2-IODOANILINE manufacturers
- Product
- 4-BROMO-2-IODOANILINE 66416-72-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-25