ChemicalBook > CAS DataBase List > 4-BROMO-2-IODOANILINE

4-BROMO-2-IODOANILINE

Product Name: 4-BROMO-2-IODOANILINE
CAS No.: 66416-72-6
Chemical Name: 4-BROMO-2-IODOANILINE
Synonyms: AKOS BB-7878;ASISCHEM T54343;4-BROMO-2-IODOANILINE;2-Iodine-4-bromoaniline;4-Bromo-2-iodoaNAine, 97%;4-Bromo-2-iodoaniline >4-Bromo-2-iodoaniline,97%;4-Bromo-2-iodoaniline 97%;4-BROMO-2-IODO-PHENYLAMINE;4-bromo-2-iodo-benzenamine
CBNumber: CB8248299
Molecular Formula: C6H5BrIN
Formula Weight: 297.92
MOL File: 66416-72-6.mol

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4-BROMO-2-IODOANILINE Property

Melting point:: 69-72 °C(lit.)
Boiling point:: 297.9±30.0 °C(Predicted)
Density: 2.292±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: soluble in Methanol
pka: 1.83±0.10(Predicted)
form: Powder
color: Gray to purple
InChI: InChI=1S/C6H5BrIN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
InChIKey: HHTYEQWCHQEJNV-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(Br)C=C1I
CAS DataBase Reference: 66416-72-6(CAS DataBase Reference)

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Safety

Hazard Codes: T,N,Xi
Risk Statements: 25-37/38-41-51/53
Safety Statements: 26-36/37/39-45-61
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 29214200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 523267
Product name: 4-Bromo-2-iodoaniline
Purity: 97%
Packaging: 5g
Price: $71.06
Updated: 2025/07/31

TCI Chemical

Product number: B3164
Product name: 4-Bromo-2-iodoaniline
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $22
Updated: 2025/07/31

TCI Chemical

Product number: B3164
Product name: 4-Bromo-2-iodoaniline
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $64
Updated: 2025/07/31

TRC

Product number: B687523
Product name: 4-Bromo-2-iodoaniline
Packaging: 10g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB70320
Product name: 4-Bromo-2-iodoaniline
Packaging: 25g
Price: $70
Updated: 2021/12/16

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4-BROMO-2-IODOANILINE Chemical Properties,Usage,Production

Chemical Properties

Grey to purple powder

Uses

4-Bromo-2-iodoaniline may be used in the following:

Preparation of quinolone derivatives.
Synthesis of a resin-bound sulfonamide, which was used as a starting material for the preparation of 2,3,5-trisubstituted indoles.

General Description

4-Bromo-2-iodoaniline is a 2-iodoaniline derivative. It can be prepared by reacting 4-bromoaniline with iodine.

Synthesis

106-40-1

66416-72-6

General procedure: Iodination of aryl amines was carried out under solvent-free conditions. DBDABCODCI (0.5 mmol) was co-milled with 4-bromoaniline (1 mmol) in a porcelain mortar at room temperature. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, ethyl acetate was added to the mixture and subsequently filtered. The organic layer was washed with 5% aqueous sodium thiosulfate and dried with anhydrous magnesium sulfate. The solvent was removed under reduced pressure and the resulting crude product was purified by column chromatography, the eluent being a solvent mixture of ethyl acetate and hexane. The purified product was characterized by melting point determination and 1H NMR spectroscopy.

References

[1] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 2, p. 600 - 602
[2] Bulletin of the Chemical Society of Ethiopia, 2015, vol. 29, # 1, p. 157 - 162
[3] RSC Advances, 2018, vol. 8, # 54, p. 30761 - 30776
[4] Synthesis, 2008, # 13, p. 2039 - 2044
[5] Patent: US9212182, 2015, B2. Location in patent: Page/Page column 198; 199

4-BROMO-2-IODOANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-BROMO-2-IODOANILINE manufacturers

Career Henan Chemical Co

Product: 4-BROMO-2-IODOANILINE 66416-72-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

66416-72-6, 4-BROMO-2-IODOANILINERelated Search:

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ASISCHEM T54343

4-BROMO-2-IODOANILINE

4-BROMO-2-IODO-PHENYLAMINE

AKOS BB-7878

4-Bromo-2-iodoaniline 97%

4-bromo-2-iodo-benzenamine

BenzenaMine, 4-broMo-2-iodo-

4-Bromo-2-iodoaniline,97%

4-Bromo-2-iodoaniline &gt

4-BROMO-2-IODOANILINE ISO 9001：2015 REACH

4-Bromo-2-iodoaNAine, 97%

2-Iodine-4-bromoaniline

66416-72-6

BrC6H3INH2

Organic Building Blocks

Nitrogen Compounds

Building Blocks

Amines

C2 to C6

Anilines, Aromatic Amines and Nitro Compounds

Anilines, Amides & Amines

Bromine Compounds

Iodine Compounds

Amines

C2 to C6

Nitrogen Compounds