ChemicalBook > CAS DataBase List > Monoclonal antibody 6B1 igg4
Monoclonal antibody 6B1 igg4
- Product Name
- Monoclonal antibody 6B1 igg4
- CAS No.
- 285985-06-0
- Chemical Name
- Monoclonal antibody 6B1 igg4
- Synonyms
- Cat-152;Lerdelimumab;Lerdelimumab [inn];Research Grade Lerdelimumab;Monoclonal antibody 6B1 igg4;Human igg-4 anti-tgfb2 monoclonal antibody;Human igg4 anti-transforming growth factor-beta 2 monoclonal antibody
- CBNumber
- CB82492997
- Formula Weight
- 0
- MOL File
- Mol file
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Monoclonal antibody 6B1 igg4 Chemical Properties,Usage,Production
Uses
Lerdelimumab (CAT-152) is an IgG4 human anti-TGF-β2 recombinant monoclonal antibody. Lerdelimumab can be used as an anti-scarring agent for glaucoma research[1][2].
in vivo
Lerdelimumab (100 μL, 1 mg/mL; subconjunctival injection; on days 2, 3, 4, 7, 9, 11 and 14 after surgery) significantly improves glaucoma surgical outcome and reduces the risk of corneal side effects[1].
References
[1] Mead AL, et al. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3394-401. DOI:10.1167/iovs.02-0978
[2] Wormstone IM, et al. TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag. Invest Ophthalmol Vis Sci. PMID:12091431
Monoclonal antibody 6B1 igg4 Preparation Products And Raw materials
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Preparation Products
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