2-Amino-3-bromo-6-chloropyrazine
- Product Name
- 2-Amino-3-bromo-6-chloropyrazine
- CAS No.
- 212779-21-0
- Chemical Name
- 2-Amino-3-bromo-6-chloropyrazine
- Synonyms
- 104365;2-Amino-3-bromo-6-chL;3-Bromo-6-chloro-2-pyrazinamine;2-Amino-3-bromo-6-chloropyrazine;2-PyrazinaMine, 3-broMo-6-chloro-;3-Bromo-6-chloro-pyrazin-2-ylamine;2-Amino-3-bromo-6-chloropyrazine ISO 9001:2015 REACH
- CBNumber
- CB82500753
- Molecular Formula
- C4H3BrClN3
- Formula Weight
- 208.44
- MOL File
- 212779-21-0.mol
2-Amino-3-bromo-6-chloropyrazine Property
- Boiling point:
- 299.5±35.0 °C(Predicted)
- Density
- 1.960
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.05±0.10(Predicted)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A594275
- Product name
- 2-Amino-3-bromo-6-chloropyrazine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 414996
- Product name
- 2-Amino-3-bromo-6-chloropyrazine
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- J96339
- Product name
- 2-Amino-3-bromo-6-chloropyrazine
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
- Product number
- FA75138
- Product name
- 2-Amino-3-bromo-6-chloropyrazine
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FA75138
- Product name
- 2-Amino-3-bromo-6-chloropyrazine
- Packaging
- 2g
- Price
- $100
- Updated
- 2021/12/16
2-Amino-3-bromo-6-chloropyrazine Chemical Properties,Usage,Production
Uses
2-amino-3-bromo-6-chloropyrazine has essential applications in the pharmaceutical industry and is an important intermediate for synthesizing an anti-tumor medicament SHP2 inhibitor.
Preparation
Currently, in thepreparing 2-amino-3-bromo-6-chloropyrazine, the 2-amino-6-chloropyrazine is mainly obtained by a one-step bromination reaction. According to the method, bromine is mainly positioned at an amino para position due to the activation effect of amino; generated byproducts are mainly 2-bromo-3-chloro-5-aminopyrazine and partial dibromo byproduct 2-amino-3, 5-dibromo-6-chloropyrazine, the product 2-amino-3-bromo-6-chloro is less, the yield is low. A process for preparing 2-amino-3-bromo-6-chloropyrazine uses 3-aminopyrazine-2-carboxylate as raw material and includes such steps as chlorination, diazotization bromination, ester hydrolysis, carboxyl rearrangement and removing tert-butyloxycarbonyl.
2-Amino-3-bromo-6-chloropyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-3-bromo-6-chloropyrazine Suppliers
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- 28-83379370 13880556291
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View Lastest Price from 2-Amino-3-bromo-6-chloropyrazine manufacturers
- Product
- 2-Amino-3-bromo-6-chloropyrazine 212779-21-0
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2021-09-14
- Product
- 3-bromo-6-chloropyrazin-2-amine 212779-21-0
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10KG
- Release date
- 2021-09-16
- Product
- 2-Amino-3-bromo-6-chloropyrazine 212779-21-0
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 95%-98%
- Supply Ability
- 100
- Release date
- 2019-09-04