ChemicalBook > CAS DataBase List > 2-Amino-3-bromo-6-chloropyrazine

2-Amino-3-bromo-6-chloropyrazine

Product Name
2-Amino-3-bromo-6-chloropyrazine
CAS No.
212779-21-0
Chemical Name
2-Amino-3-bromo-6-chloropyrazine
Synonyms
104365;2-Amino-3-bromo-6-chL;3-Bromo-6-chloro-2-pyrazinamine;2-Amino-3-bromo-6-chloropyrazine;2-PyrazinaMine, 3-broMo-6-chloro-;3-Bromo-6-chloro-pyrazin-2-ylamine;2-Amino-3-bromo-6-chloropyrazine ISO 9001:2015 REACH
CBNumber
CB82500753
Molecular Formula
C4H3BrClN3
Formula Weight
208.44
MOL File
212779-21-0.mol
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2-Amino-3-bromo-6-chloropyrazine Property

Boiling point:
299.5±35.0 °C(Predicted)
Density 
1.960
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
0.05±0.10(Predicted)
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A594275
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
100mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
414996
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
100mg
Price
$305
Updated
2021/12/16
AK Scientific
Product number
J96339
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
1g
Price
$25
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA75138
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
10g
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA75138
Product name
2-Amino-3-bromo-6-chloropyrazine
Packaging
25g
Price
$500
Updated
2021/12/16
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2-Amino-3-bromo-6-chloropyrazine Chemical Properties,Usage,Production

Uses

2-amino-3-bromo-6-chloropyrazine has essential applications in the pharmaceutical industry and is an important intermediate for synthesizing an anti-tumor medicament SHP2 inhibitor.

Preparation

Currently, in thepreparing 2-amino-3-bromo-6-chloropyrazine, the 2-amino-6-chloropyrazine is mainly obtained by a one-step bromination reaction. According to the method, bromine is mainly positioned at an amino para position due to the activation effect of amino; generated byproducts are mainly 2-bromo-3-chloro-5-aminopyrazine and partial dibromo byproduct 2-amino-3, 5-dibromo-6-chloropyrazine, the product 2-amino-3-bromo-6-chloro is less, the yield is low. A process for preparing 2-amino-3-bromo-6-chloropyrazine uses 3-aminopyrazine-2-carboxylate as raw material and includes such steps as chlorination, diazotization bromination, ester hydrolysis, carboxyl rearrangement and removing tert-butyloxycarbonyl.

2-Amino-3-bromo-6-chloropyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3-bromo-6-chloropyrazine Suppliers

ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
28-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
510
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Carbott PharmTech Inc.
Tel
0535-6385396
Fax
+86 (535) 638-9971
Email
info@carbottpharm.com
Country
China
ProdList
921
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1347
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from 2-Amino-3-bromo-6-chloropyrazine manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
2-Amino-3-bromo-6-chloropyrazine 212779-21-0
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
3-bromo-6-chloropyrazin-2-amine 212779-21-0
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10KG
Release date
2021-09-16
Career Henan Chemical Co
Product
2-Amino-3-bromo-6-chloropyrazine 212779-21-0
Price
US $6.00/KG
Min. Order
1KG
Purity
95%-98%
Supply Ability
100
Release date
2019-09-04

212779-21-0, 2-Amino-3-bromo-6-chloropyrazineRelated Search:


  • 104365
  • 2-PyrazinaMine, 3-broMo-6-chloro-
  • 3-Bromo-6-chloro-2-pyrazinamine
  • 3-Bromo-6-chloro-pyrazin-2-ylamine
  • 2-Amino-3-bromo-6-chloropyrazine
  • 2-Amino-3-bromo-6-chL
  • 2-Amino-3-bromo-6-chloropyrazine ISO 9001:2015 REACH
  • 212779-21-0