PTEROIC ACID

Product Name: PTEROIC ACID
CAS No.: 119-24-4
Chemical Name: PTEROIC ACID
Synonyms: 4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid;Pyrofolic acid;4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid;NSC 14972;PTEROIC ACID;Butterfly acid;Pteroic Acid (>Pteroic acid >=93%;Pteroic Acid (>85%);Folic acid iMpurity D
CBNumber: CB8254618
Molecular Formula: C14H12N6O3
Formula Weight: 312.28
MOL File: 119-24-4.mol

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PTEROIC ACID Property

Melting point:: >400℃
Boiling point:: 610.0±65.0 °C(Predicted)
Density: 1.69
storage temp.: 2-8°C
solubility: Aqueous Base (Slightly), DMSO (Slightly)
pka: 4.65±0.10(Predicted)
color: Light Yellow to Brown

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Safety

WGK Germany: 3
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P1781
Product name: Pteroic acid
Purity: ≥93%
Packaging: 25mg
Price: $81.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1781
Product name: Pteroic acid
Purity: ≥93%
Packaging: 50mg
Price: $131
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2002
Product name: Folic Acid Impurity D
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 100mg
Price: $647
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001243
Product name: Folic acid impurity D
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001243
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1781
Product name: Pteroic acid
Purity: ≥93%
Packaging: 100mg
Price: $255
Updated: 2024/03/01

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PTEROIC ACID Chemical Properties,Usage,Production

Uses

Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.

Uses

Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.

Definition

ChEBI: 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid is a pteroic acid. It is functionally related to a 2-aminopteridin-4-ol. It is a conjugate base of a 2-amino-6-{[(4-carboxyphenyl)amino]methyl}-4-hydroxypteridin-1-ium. It is a conjugate acid of a 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoate. It is a tautomer of a 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid and a 4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoic acid.

General Description

Folic Acid Impurity D is an impurity of the water-soluble B-vitamin, folic acid. Folic Acid is generally used in the treatment of certain types of anemia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Enzyme inhibitor

This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.

Purification Methods

Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]

PTEROIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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PTEROIC ACID Suppliers

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View Lastest Price from PTEROIC ACID manufacturers

Wuhan Demeikai Biotechnology Co., Ltd

Product: Pteroic Acid 119-24-4
Price: US $10.00/g/Bag
Min. Order: 10g
Purity: 99
Supply Ability: 100KG
Release date: 2021-11-16

Hebei Minshang Biological Technology Co. LTD

Product: Pteroic Acid 119-24-4
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000t
Release date: 2021-05-07

Career Henan Chemical Co

Product: PTEROIC ACID 119-24-4
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2018-08-15

119-24-4, PTEROIC ACIDRelated Search:

(2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid 2-Amino-7-(chloromethyl)pteridin-4(1H)-one 2-Amino-4-hydroxy-1H-pteridine Erinacine A Erinacin A 5-formyl-5,6,7,8-tetrahydropteroic acid 2-Amino-6-(chloromethyl)-4(3H)-pteridinone Folitixorin (Mixture of DiastereoMers) N-(4-aminobenzoyl)- D-Glutamic acid Folic acid 5-Methyl Tetrahedropteroic Acid (Mixture of DiastereoMers) Folic Acid Impurity C N-(p-Aminobenzoyl)glutamic acid folic acid 5-Methyltetrahydrofolic acid 10-Formylfolic Acid Folinic acid 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE L-Tetrahydrofolic Acid

4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid

4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid

4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid

4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid

4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid

NSC 14972

p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid

Pyrofolic acid

Benzoic acid, 4-[[(2-aMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]-

4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid

Folic acid iMpurity D

Folic acid iMpurity D Pteroic acid

Pteroic Acid (>85%)

Pteroic acid - min95%

Pteroic acid >=93%

NSC 14972 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid

4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)

PTEROIC ACID

p-((2-amino-4-hydroxypteridin-6-yl)methylamino)benzoic acid

PTEROIC ACID HYDRATE, 90%

Folic acid EP Impurity D

Folic Acid Impurity 6

Pteroic acid(Instant type)

Methotrexate EP Impurity D N-Desmethyl Impurity

4-(((2-amino-4-hydroxypteridin-6-yl)

Folic acid impurity D CRS

4-[[(2-Amino-4-oxo-1,4-dihydropteri

Pteroic Acid (&gt

Methotrexate EP Impurity D Desmethyl Impurity

Folic Acid Impurity 6（Folic Acid EP Impurity D）

4-[(2-amino-4-oxo-8H-pteridin-6-yl)methylamino]benzoic acid

Folic acid impurity DQ: What is Folic acid impurity D Q: What is the CAS Number of Folic acid impurity D Q: What is the storage condition of Folic acid impurity D Q: What are the applications of Folic acid impurity D

4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid(119-24-4)

Butterfly acid

4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoicaci

Pteroic acid (7CI, 8CI)

Folic Acid Hydrate Impurity D

Folic Acid Hydrate EP Impurity D

119-24-4

C14H12N6O3

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