2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate

Product Name: 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
CAS No.: 1041026-71-4
Chemical Name: 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
Synonyms: tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate;tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1);2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate;6-diazaspiro[3.3]heptane-2-carboxylate oxalate;1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%;1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%;2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1);2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate;ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate;tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
CBNumber: CB82548539
Molecular Formula: C22H38N4O8
Formula Weight: 486.56
MOL File: 1041026-71-4.mol

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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Property

Melting point:: 206-209℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
form: Solid
color: White to Off-White
Water Solubility: Slightly soluble in water.
Stability:: Hygroscopic

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Alfa Aesar

Product number: H63763
Product name: 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97%
Packaging: 250mg
Price: $163
Updated: 2023/06/20

Alfa Aesar

Product number: H63763
Product name: 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97%
Packaging: 1g
Price: $519
Updated: 2023/06/20

TRC

Product number: D417620
Product name: 2,6-Diazaspiro[3.3]heptane-2-carboxylicAcidtert-ButylEsterHemioxalate
Packaging: 100mg
Price: $70
Updated: 2021/12/16

Synthonix

Product number: D6051
Product name: 2,6-Diazaspiro[3.3]heptane-2-carboxylicacidtert-butylesterhemioxalate
Purity: 97.0%
Packaging: 1g
Price: $30
Updated: 2021/12/16

Apolloscientific

Product number: OR312002
Product name: 2,6-Diazaspiro[3.3]heptane,N2-BOCprotectedhemioxalate
Purity: 97%
Packaging: 1g
Price: $58
Updated: 2021/12/16

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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Chemical Properties,Usage,Production

Chemical Properties

white to yellow Solid.

Uses

It is employed as a intermediate for pharmaceutical.

Uses

2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.

Preparation

Synthesis of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate: Take a 500mL single-necked bottle, add 6-toluenesulfonyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester (7g, 20mmol), dissolve in methanol (200mL), add magnesium chips (3.84 g) g, 0.16 mol, 8 equiv) and stirred at room temperature. The reaction solution gradually turned into a white viscous state with the dissolution of the magnesium scraps, and TLC showed that the reaction of the raw materials was completed. The solvent was removed by rotary evaporation, ether (150 mL) was added, stirred at room temperature for 1 h, filtered through celite, the filtrate was dried over anhydrous sodium sulfate, and an ethanol solution (3 mL) of anhydrous oxalic acid (0.89 g, 9.9 mmol, 0.5 equiv) was added dropwise, A white precipitate appeared immediately, which was filtered under reduced pressure to give 3.2 g of a colorless solid, 82%.

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Suppliers

China 142 India 1 United Kingdom 1 United States 9 Global 153

Hefei zhongxing Biomedical Co., Ltd.

Tel: 15955174703
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Hefei Xiuhe Biotechnology Co. Ltd.

Tel: 0551-62887095 13856031416
Email: 65854417@qq.com
Country: China
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Suzhou Victorypharm Co.,Ltd.

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Shandong Shenganbei New Energy Co. , Ltd. . Nanjing branch

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PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
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Energy Chemical

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Beijing Ouhe Technology Co., Ltd

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Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
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Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376090521
Fax: 025-85766769
Email: sales@habotech.com
Country: China
ProdList: 996
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View Lastest Price from 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate 1041026-71-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97%min
Supply Ability: 10KG
Release date: 2021-10-21

Career Henan Chemical Co

Product: tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate 1041026-71-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

1041026-71-4, 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylateRelated Search:

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2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid ethanedioate, 1,1-dimethylethyl ester

tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester heMioxylate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, ethanedioate (2:1)

1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate, hemioxalate salt

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, heMioxalate

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1)

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester ethanedioate

tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate

2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate

2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester, oxalic acid salt

2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate

2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxalate

2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate (2:1)

1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%

2,6-diazo-heterospiro [3,3] heptane-2-carboxylic acid tert-butyl semicarbamate

6-diazaspiro[3.3]heptane-2-carboxylate oxalate

3-Oxazolidinecarboxylicacid,2,2-dimethyl-4-(2-oxoethyl)-,1,1-dimethylethylester,(10S)-

2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1)

ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate

tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate semioxalate

1041026-71-4

2C10H18N2O2C2H2O4