2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- Product Name
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- CAS No.
- 1041026-71-4
- Chemical Name
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- Synonyms
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate;tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1);2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate;6-diazaspiro[3.3]heptane-2-carboxylate oxalate;1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%;1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%;2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1);2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate;ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate;tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
- CBNumber
- CB82548539
- Molecular Formula
- C22H38N4O8
- Formula Weight
- 486.56
- MOL File
- 1041026-71-4.mol
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Property
- Melting point:
- 206-209℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Slightly soluble in water.
- Stability:
- Hygroscopic
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P321Specific treatment (see … on this label).
N-Bromosuccinimide Price
- Product number
- H63763
- Product name
- 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97%
- Packaging
- 250mg
- Price
- $163
- Updated
- 2023/06/20
- Product number
- H63763
- Product name
- 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97%
- Packaging
- 1g
- Price
- $519
- Updated
- 2023/06/20
- Product number
- D417620
- Product name
- 2,6-Diazaspiro[3.3]heptane-2-carboxylicAcidtert-ButylEsterHemioxalate
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- D6051
- Product name
- 2,6-Diazaspiro[3.3]heptane-2-carboxylicacidtert-butylesterhemioxalate
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $30
- Updated
- 2021/12/16
- Product number
- OR312002
- Product name
- 2,6-Diazaspiro[3.3]heptane,N2-BOCprotectedhemioxalate
- Purity
- 97%
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Chemical Properties,Usage,Production
Chemical Properties
white to yellow Solid.
Uses
It is employed as a intermediate for pharmaceutical.
Uses
2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.
Preparation
Synthesis of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate: Take a 500mL single-necked bottle, add 6-toluenesulfonyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester (7g, 20mmol), dissolve in methanol (200mL), add magnesium chips (3.84 g) g, 0.16 mol, 8 equiv) and stirred at room temperature. The reaction solution gradually turned into a white viscous state with the dissolution of the magnesium scraps, and TLC showed that the reaction of the raw materials was completed. The solvent was removed by rotary evaporation, ether (150 mL) was added, stirred at room temperature for 1 h, filtered through celite, the filtrate was dried over anhydrous sodium sulfate, and an ethanol solution (3 mL) of anhydrous oxalic acid (0.89 g, 9.9 mmol, 0.5 equiv) was added dropwise, A white precipitate appeared immediately, which was filtered under reduced pressure to give 3.2 g of a colorless solid, 82%.
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Suppliers
- Tel
- 15055708011 15055708011
- 2093564781@qq.com
- Country
- China
- ProdList
- 343
- Advantage
- 58
- Tel
- 15955174703
- Fax
- -
- 149498276@qq.com
- Country
- China
- ProdList
- 80
- Advantage
- 58
- Tel
- 0551-62887095 13856031416
- 65854417@qq.com
- Country
- China
- ProdList
- 174
- Advantage
- 58
- Tel
- 18914494296
- sab202211@163.com
- Country
- China
- ProdList
- 1603
- Advantage
- 58
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 4986
- Advantage
- 55
- Tel
- 0760-+86-0760-88665202 13824707890
- kexinBiotec@163.com
- Country
- China
- ProdList
- 139
- Advantage
- 58
- Tel
- 0551-68136310 18705595789
- Fax
- 0551-68136307
- 939249921@qq.com
- Country
- China
- ProdList
- 42
- Advantage
- 55
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44688
- Advantage
- 61
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12390
- Advantage
- 60
View Lastest Price from 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate manufacturers
- Product
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate 1041026-71-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97%min
- Supply Ability
- 10KG
- Release date
- 2021-10-21
- Product
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate 1041026-71-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500KG
- Release date
- 2018-08-19