L-Ribose

Product Name: L-Ribose
CAS No.: 24259-59-4
Chemical Name: L-Ribose
Synonyms: L-RIBOSE;Ribose;L - RNA;L-D-Ribose;L-(+)-Ribos;L-(+)-RIBOSE;z052L-Ribose;L-Ribose >L-Ribose ,98%;L-PLUS-RIBOSE
CBNumber: CB8256607
Molecular Formula: C5H10O5
Formula Weight: 150.13
MOL File: 24259-59-4.mol

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L-Ribose Property

Melting point:: 81-82 °C(lit.)
alpha: 20 º (c=2,water)
Boiling point:: 191.65°C (rough estimate)
Density: 1.1897 (rough estimate)
refractive index: 20 ° (C=1, H2O)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
pka: 12.22(at 25℃)
color: White to Off-White
Water Solubility: Soluble in water (100 mg/ml).
BRN: 1723084
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 24259-59-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-37-36-36/38
Safety Statements: 24/25-36-26-37/39
WGK Germany: 3
RTECS: 246-110-4
F: 3-10
HS Code: 29400000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R4377
Product name: L-(+)-Ribose
Packaging: 1g
Price: $591
Updated: 2024/03/01

TCI Chemical

Product number: R0068
Product name: L-Ribose
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: R0068
Product name: L-Ribose
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $40
Updated: 2024/03/01

Alfa Aesar

Product number: B21117
Product name: L-(+)-Ribose, 99%
Packaging: 1g
Price: $133.65
Updated: 2024/03/01

Alfa Aesar

Product number: B21117
Product name: L-(+)-Ribose, 99%
Packaging: 5g
Price: $538
Updated: 2021/12/16

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L-Ribose Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Uses

L-[1-13C]ribose is a compound useful in organic synthesis.

Uses

It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate.

Definition

A monosaccharide; a component of RNA.

Definition

ribose: A monosaccharide, C₅H₁₀O₅, rarely occurring free in nature but important as a component of RNA (ribonucleic acid). Its derivative deoxyribose, C₅H₁₀O₄, is equally important as a constituent of DNA (deoxyribonucleic acid), which carries the genetic code in chromosomes.

Biosynthesis

L-ribose is the enantiomer of D-ribose, which occurs naturally. It is a building block of many novel nucleotide analogue anti-viral drugs. Bio-production of L-ribose relies on a two-step reaction: (i) conversion of L-arabinose to L-ribulose by the catalytic action of L-arabinose isomerase (L-AI) and (ii) conversion of L-ribulose to L-ribose by the catalytic action of L-ribose isomerase (L-RI, EC 5.3.1.B3) or mannose-6-phosphate isomerase (MPI, EC 5.3.1.8, alternately named as phosphomannose isomerase). Among the two enzymes, L-RI is a rare enzyme discovered in 1996 by Professor Izumori's group, whereas MPI is an essential enzyme in metabolic pathways in humans and microorganisms[1].

Synthesis

A method for converting inexpensive, naturally occurring D-ribose into L-ribose is by interconverting the hydroxy group at Cl and the hydroxymethyl group at C5. L-Ribose is prepared from D-ribose by (a) forming a hydroxy-protected D-ribose, (b) reducing the hydroxy-protected D-ribose to a protected tetrol, (c) converting the tetrol to a tetraester, such as a tetraacetate; (d) hydrolyzing the protecting group to form a hydroxymethyl tetraester; (e) oxidizing the hydroxymethyl group to form a tetraester aldehyde; and (f) hydrolysing the ester groups to yield L-ribose.

References

[1] M. Helanto. “Biotechnological production of l-ribose from l-arabinose.” Applied Microbiology and Biotechnology 83 1 (2009): 77–83.

L-Ribose Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Ribose Suppliers

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View Lastest Price from L-Ribose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Ribose 24259-59-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 5000kg/month
Release date: 2023-01-06

Hebei Weibang Biotechnology Co., Ltd

Product: Ribose 24259-59-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-04

Shanghai Standard Technology Co., Ltd.

Product: L-Ribose 24259-59-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-01-20

24259-59-4, L-RiboseRelated Search:

Ribonucleic acid L-Arabinopyranose RIBOSE, D-(-)- DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* ribonucleic acid for injection 6-O-(TRIISOPROPYLSILYL)-D-GALACTAL CYCLIC CARBONATE D-TALOSE DNA polymeraseⅠfrom E.coli METHYL 2-DEOXY-D-RIBOSE DnaseⅠ Deoxycytidine triphosphate trisodium salt RIBONIC ACID POLY ADP-RIBOSE POLYMERASE 3'-GMP DISODIUM SALT CAD（Caspase-Activated Deoxyribonuclease） DNA，plasmid pSP64 2'-DEOXYURIDINE 5'-TRIPHOSPHATE SODIUM SALT 1,3,5-Tri-O-benzoyl-D-ribofuranose

(2S,3S,4S)-2,3,4,5-Tetrahydroxypentanal

L-Ribose ,98%

L-(+)-Ribos

(2R,3S,4R,5S)-5-(hydroxymethyl)oxolane-2,3,4-triol

L-D-Ribose

l-[1-13C]ribose

l-[UL-13C5]ribose

aldehydo-L-ribose

L-(+)-RIBOSE

L-RIBOSE

Ribose

L-PLUS-RIBOSE

L-Ribose (9CI)

L-(+)-Ribose,99%

z052L-Ribose

L-Ribose &gt

Ribose USP/EP/BP

L - RNA

L-Ribose (9CI, ACI)

24259-59-4

24295-59-4

24529-59-4

Carbohydrate Synthesis

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Sugars

Monosaccharides

Specialty Synthesis

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MonosaccharideSpecialty Synthesis

Carbohydrate Synthesis

Carbohydrates

Carbohydrates A to

Carbohydrates P-ZBiochemicals and Reagents

13C & 2H Sugars

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Biochemistry

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Ribose

Riboses and 2'-Deoxyriboses

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CARBOHYDRATE

Sugars, Carbohydrates & Glucosides

bc0001

Glycon Biochem