NEUROPEPTIDE Y (3-36) (PORCINE)
- Product Name
- NEUROPEPTIDE Y (3-36) (PORCINE)
- CAS No.
- 143863-88-1
- Chemical Name
- NEUROPEPTIDE Y (3-36) (PORCINE)
- Synonyms
- NPY (3-36) (PORCINE);3-36-Neuropeptide Y(pig);3-36-Neuropeptide Y(swine);neuropeptide Y fragment 3-36;NEUROPEPTIDE Y (3-36) (PORCINE);NEUROPEPTIDE Y FRAGMENT 3-36 PORCINE;SKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2;NEUROPEPTIDE Y FRAGMENT 3-36, HUMAN,*POR CINE;SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2;H-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
- CBNumber
- CB8258085
- Molecular Formula
- C176H271N53O54
- Formula Weight
- 3993.36
- MOL File
- Mol file
NEUROPEPTIDE Y (3-36) (PORCINE) Property
- storage temp.
- −20°C
Safety
- WGK Germany
- 3
NEUROPEPTIDE Y (3-36) (PORCINE) Chemical Properties,Usage,Production
Uses
Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3].
in vivo
Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner[1].
Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)[2].
| Animal Model: | Adult male Wistar rats (250-300 g)[1] |
| Dosage: | 0.24, 0.72, 2.4, 7.2, 24 nM per animal |
| Administration: | Intracerebroventricular injection; single dose |
| Result: | Stimulated rat feeding dose-dependently. Produced no feeding effect alone, that Y2 activation alone elicited no feeding response. |
IC 50
NPY Y2 receptor
References
[1] O'Shea D, et al. Neuropeptide Y induced feeding in the rat is mediated by a novel receptor. Endocrinology. 1997 Jan;138(1):196-202. DOI:10.1210/endo.138.1.4899
[2] Grandt D, et al. Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul Pept. 1996 Nov 14;67(1):33-7. DOI:10.1016/s0167-0115(96)00104-8
[3] M Aldegunde, et al. Effects of neuropeptide Y on food intake and brain biogenic amines in the rainbow trout (Oncorhynchus mykiss), Peptides. 2006; 27(4):719-727. DOI:10.1016/j.peptides.2005.09.014
NEUROPEPTIDE Y (3-36) (PORCINE) Preparation Products And Raw materials
Raw materials
Preparation Products
NEUROPEPTIDE Y (3-36) (PORCINE) Suppliers
- Tel
- --
- Fax
- --
- info@polypeptide.de
- Country
- Germany
- ProdList
- 408
- Advantage
- 66
View Lastest Price from NEUROPEPTIDE Y (3-36) (PORCINE) manufacturers
- Product
- NEUROPEPTIDE Y (3-36) (PORCINE) 143863-88-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05