ChemicalBook > CAS DataBase List > GI 254023X
GI 254023X
- Product Name
- GI 254023X
- CAS No.
- 260264-93-5
- Chemical Name
- GI 254023X
- Synonyms
- GI4023;GI 254023X;SRI 028594);GI 254023X(GI 4023;GI 254023X;GI-254023X;GI4023;SRI028594;GI254023X; GI 254023X; GI-254023X;GI4023; GI-4023; GI 4023;(R)-N-((S)-3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl)-2-((S)-1-(N-hydroxyformamido)ethyl)-5-phenylpentanamide;(2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-2-[(1S)-1-(N-hydroxyformamido)ethyl]-5-phenylpentanamide;Benzenepentanamide, N-[(1S)-2,2-dimethyl-1-[(methylamino)carbonyl]propyl]-α-[(1S)-1-(formylhydroxyamino)ethyl]-, (αR)-;(2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]-propyl]-2-[(1S)-1-[formyl(hydroxy)amino]ethyl]-5-phenylpentanamide
- CBNumber
- CB82650737
- Molecular Formula
- C21H33N3O4
- Formula Weight
- 391.51
- MOL File
- 260264-93-5.mol
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GI 254023X Property
- Density
- 1.112±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble15mg/mL, clear
- pka
- 8.48±0.69(Predicted)
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0789
- Product name
- GI254023X
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $212
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0789
- Product name
- GI254023X
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $847
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28284
- Product name
- GI 254023X
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28284
- Product name
- GI 254023X
- Packaging
- 25mg
- Price
- $479
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28284
- Product name
- GI 254023X
- Packaging
- 5mg
- Price
- $166
- Updated
- 2024/03/01
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GI 254023X Chemical Properties,Usage,Production
Uses
GI 254023X is an ADAM10 metaloproteinase inhibitor.
Uses
GI254023X has been used to inhibit ADAM10 (ADAM metallopeptidase domain 10).
Definition
ChEBI: GI254023X is a L-valine derivative that is 3-methyl-L-valine in which carboxy OH group is replaced by a methylnitrilo group and the one of the amino hydrogens is replaced by a (2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl group. It is a potent MMP9 and ADAM10 metalloprotease inhibitor with IC50 of 2.5 and 5.3 nM, respectively. It has a role as an apoptosis inducer, an antineoplastic agent, a matrix metalloproteinase inhibitor and an EC 3.4.24.* (metalloendopeptidase) inhibitor. It is a L-valine derivative, an aldehyde and a member of hydroxylamines.
Biochem/physiol Actions
GI254023X is a potent and selective ADAM10 metalloproteinase inhibitor.
storage
Store at -20°C
GI 254023X Preparation Products And Raw materials
Raw materials
Preparation Products
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GI 254023X Suppliers
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