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(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL

Product Name
(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL
CAS No.
57794-08-8
Chemical Name
(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL
Synonyms
(1S,2S)-cyclohexane-1,2-diol;(S,S)-(+)-1,2-CYCLOHEXANEDIOL;1,2-Cyclohexanediol, (1S,2S)-;(1S,2S)-1α,2β-Cyclohexanediol;(1S)-TRANS-1,2-CYCLOHEXANEDIOL;[1S,2S,(+)]-1,2-Cyclohexanediol;(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL;(1S,2S)-trans-1,2-Cyclohexanediol,98%;(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL 98%;(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL, 99% ( 99% EE/GLC)
CBNumber
CB8265320
Molecular Formula
C6H12O2
Formula Weight
116.16
MOL File
57794-08-8.mol
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(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL Property

Melting point:
107-109 °C(lit.)
Boiling point:
177.22°C (rough estimate)
Density 
0.9958 (rough estimate)
refractive index 
1.4270 (estimate)
Flash point:
134 °C
pka
14.49±0.40(Predicted)
optical activity
[α]20/D +39°, c = 1.6 in H2O
BRN 
1901343
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37-41
Safety Statements 
26-39
WGK Germany 
3
HS Code 
29061990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
421804
Product name
(1S,2S)-trans-1,2-Cyclohexanediol
Purity
99%
Packaging
250mg
Price
$122
Updated
2024/03/01
Sigma-Aldrich
Product number
421804
Product name
(1S,2S)-trans-1,2-Cyclohexanediol
Purity
99%
Packaging
1g
Price
$382
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0004498
Product name
(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL
Purity
95.00%
Packaging
250MG
Price
$636.21
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0004498
Product name
(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL
Purity
95.00%
Packaging
1G
Price
$902.29
Updated
2021/12/16
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(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystals

Uses

(1S,2S)-trans-1,2-Cyclohexanediol may be used in the preparation of (1S,2S)-1,2-cyclohexanediyl bis(4-vinylbenzoate) by reacting with 4-vinylbenzoyl chloride. It may also be used as a chiral ligand for the preparation of non-racemic hydroxy phosphonates via titanium alkoxide-catalyzed addition of dimethyl phosphite to the corresponding aldehydes.

Purification Methods

The enantiomers have been recrystallised from *C6H6 or EtOAc. The (±) diol has been resolved via the distrychnine salt of the hemisulfate [Hayward et al. J Chem Soc Perkin Trans 1 2413 1976], or the 1-menthoxy acetates. {l-trans-diastereoisomer has m 64o, []D -91.7o (c 1.4 EtOH) from pet ether or aqueous EtOH and yields the (-)-trans-diol } and {d-trans-diastereoisomer has m 126-127o, []D -32.7o (c 0.8 EtOH) from pet ether or aqueous EtOH and yields the (+)-trans diol}. The bis-4-nitrobenzoate has m 126.5o []D (-) and (+) 25.5o (c 1.1 CHCl3), and the bis-3,5-dinitrobenzoate has m 160o []D ± 83.0o (c 1.8 CHCl3) [Wilson & Read J Chem Soc 1269 1935]. [Beilstein 6 III 4060.]

(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL Suppliers

Belgium 1 China 29 France 1 Germany 1 Japan 1 Switzerland 1 United States 6 Global 40
Interchim S.A.
Tel
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Fax
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Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76

57794-08-8, (1S,2S)-TRANS-1,2-CYCLOHEXANEDIOLRelated Search:

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Geneticin L-QUEBRACHITOL Inositol nicotinate MYO-INOSITOL 2-MONOPHOSPHATE DI(CYCLOHEXYLAMMONIUM) SALT VERATRINE Spectinomycin FORSKOLIN, 7-DEACETYL-7-O-HEMISUCCINYL- Neomycin sulfate RIBOSTAMYCIN SULFATE SALT Streptomycin sulfate (+/-)-TRANS-1,2-CYCLOHEXANEDIOL,TRANS-1,2-CYCLOHEXANEDIOL (1R,2R)-TRANS-1,2-CYCLOHEXANEDIOL, 99% ( 99% EE/GLC),(1R,2R)-TRANS-1,2-CYCLOHEXANEDIOL,(1R)-TRANS-1,2-CYCLOHEXANEDIOL,(1R,2R)-TRANS-1,2-CYCLOHEXANEDIOL 98% TRANS-1,4-CYCLOHEXANEDIOL TRANS-1,2-CYCLOHEXANEDIOL DIACETATE 1,2-Cyclohexanediol D-INS(1,4,5)P3, 3LI 1L-EPI-2-INOSOSE

  • (1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL
  • (1S)-TRANS-1,2-CYCLOHEXANEDIOL
  • (1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL, 99% ( 99% EE/GLC)
  • (1S,2S)-TRANS-1,2-CYCLOHEXANEDIOL 98%
  • (1S,2S)-1α,2β-Cyclohexanediol
  • [1S,2S,(+)]-1,2-Cyclohexanediol
  • (1S,2S)-trans-1,2-Cyclohexanediol,98%
  • (S,S)-(+)-1,2-CYCLOHEXANEDIOL
  • (1S,2S)-cyclohexane-1,2-diol
  • 1,2-Cyclohexanediol, (1S,2S)-
  • 57794-08-8
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