ChemicalBook > CAS DataBase List > FIIN-1

FIIN-1

Product Name
FIIN-1
CAS No.
1256152-35-8
Chemical Name
FIIN-1
Synonyms
FIIN-1;FIIN 1,FIIN1;FIIN 1 hydrochloride;N-(3-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-(4-(diethylamino)butylamino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide;2-Propenamide, N-[3-[[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-
CBNumber
CB82653864
Molecular Formula
C32H39Cl2N7O4
Formula Weight
656.6
MOL File
1256152-35-8.mol
More
Less

FIIN-1 Property

Density 
1.306±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
13.54±0.70(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
4002
Product name
FIIN1hydrochloride
Purity
≥96%(HPLC)
Packaging
10
Price
$253
Updated
2021/12/16
Tocris
Product number
4002
Product name
FIIN1hydrochloride
Purity
≥96%(HPLC)
Packaging
50
Price
$1034
Updated
2021/12/16
TRC
Product number
F336500
Product name
FIIN-1
Packaging
10mg
Price
$185
Updated
2021/12/16
Usbiological
Product number
255301
Product name
FIIN 1 hydrochloride
Packaging
10mg
Price
$516
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0008601
Product name
FIIN-1
Purity
95.00%
Packaging
5MG
Price
$450.15
Updated
2021/12/16
More
Less

FIIN-1 Chemical Properties,Usage,Production

Uses

FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1.The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.

Uses

FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1 (1).The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.

IC 50

FGFR1: 2.8 nM (Kd); FGFR2: 6.9 nM (Kd); FGFR3: 5.4 nM (Kd); FGFR4: 120 nM (Kd); FGFR1: 9.2 nM (IC50); FGFR2: 6.2 nM (IC50); FGFR3: 11.9 nM (IC50); FGFR4: 189 nM (IC50)

storage

Store at -20°C

FIIN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

FIIN-1 Suppliers

Canada 1 China 23 India 1 United Kingdom 1 United States 3 Global 29
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Shanghai SunSyn Pharmaceutical Co., Ltd.
Tel
18621020637 18621020637;
Email
sales@sunsynpharma.com
Country
China
ProdList
288
Advantage
55
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62220
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18221172427
Email
sale@fine-biotech.com
Country
China
ProdList
2772
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Proteintech China
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Shanghai Yubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
344843571@qq.com
Country
CHINA
ProdList
6655
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Beijing Baiao Innovation Technology Co., Ltd.
Tel
--
Fax
--
Email
3007606172@qq.com
Country
CHINA
ProdList
6002
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58

1256152-35-8, FIIN-1Related Search:


  • FIIN-1
  • N-(3-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-(4-(diethylamino)butylamino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide
  • FIIN 1 hydrochloride
  • FIIN 1,FIIN1
  • 2-Propenamide, N-[3-[[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-
  • 1256152-35-8
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Tyrosine Kinase Inhibitors
  • Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors