ChemicalBook > CAS DataBase List > Se-Methylselenocysteine

Se-Methylselenocysteine

Product Name
Se-Methylselenocysteine
CAS No.
26046-90-2
Chemical Name
Se-Methylselenocysteine
Synonyms
SEMC;L-Se-Methylselenocysteine;SE-METHYLSELENO-L-CYSTEINE;MSeC;SeMSC;Se MSC;SeMCys;Se-MSC;METHYLSELENO-L-CYSTEINE;SE-METHYLSELENOCYSTEINE
CBNumber
CB8265719
Molecular Formula
C4H9NO2Se
Formula Weight
182.08
MOL File
26046-90-2.mol
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Se-Methylselenocysteine Property

Melting point:
177 °C(dec.)
Boiling point:
314.1±37.0 °C(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Water (Slightly)
form 
Powder
pka
2.17±0.10(Predicted)
color 
White to slightly yellow
InChI
InChI=1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
InChIKey
XDSSPSLGNGIIHP-VKHMYHEASA-N
SMILES
C(O)(=O)[C@H](C[Se]C)N
LogP
-0.043 (est)
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Safety

Hazard Codes 
T,N
Risk Statements 
23/25-33-50/53
Safety Statements 
20/21-28-45-60-61-28A
RIDADR 
UN 3283 6.1/PG 2
WGK Germany 
3
10-23
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A634438
Product name
2-Amino-3-methylselenylPropionicAcid
Packaging
100mg
Price
$205
Updated
2021/12/16
TRC
Product number
A634438
Product name
2-Amino-3-methylselenylPropionicAcid
Packaging
250mg
Price
$405
Updated
2021/12/16
Matrix Scientific
Product number
096121
Product name
(R)-2-Amino-3-(methylselanyl)propanoic acid
Purity
95+%
Packaging
250mg
Price
$439
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK314842
Product name
Se-Methylseleno-L-cysteine
Purity
98%
Packaging
50mg
Price
$67
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK314842
Product name
Se-Methylseleno-L-cysteine
Purity
98%
Packaging
250mg
Price
$177
Updated
2021/12/16
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Se-Methylselenocysteine Chemical Properties,Usage,Production

Description

Se-methyl selenocysteine (MSC) is a naturally occurring selenium compoundwith favourable pharmacokinetic properties andth high peroral bioavailability in humans. MSC is synthesized by plants such as garlic, astragalus, onions and broccoli. Se-methylselenocysteine has been proven to have a chemo-preventive property, which is shown by several authors via various cell culture models and animal models. It has also been shown to have anti-carcinogenic properties by inducing cell cycle arrest and apoptotic cell death. It is considered a pro-drug because the compound per se is not toxic unless it is metabolized by the enzymes Kynurenine aminotransferase 1 (KYAT1), Kynurenine aminotransferase 3 (KYAT3) and cystathionine γ-lyase (CTH). Of these, KYAT1 plays a vital role in MSC metabolism.

Chemical Properties

white to slightly yellow powder

Uses

2-Amino-3-methylselenyl propionic acid is an inhibitor of DMBA-induced mammary tumors.

Definition

ChEBI: Se-methyl-L-selenocysteine is an L-alpha-amino acid compound having methylselanylmethyl as the side-chain. It has a role as an antineoplastic agent. It is a Se-methylselenocysteine, a non-proteinogenic L-alpha-amino acid and a L-selenocysteine derivative. It is a conjugate base of a Se-methyl-L-selenocysteinium. It is a conjugate acid of a Se-methyl-L-selenocysteinate. It is an enantiomer of a Se-methyl-D-selenocysteine. It is a tautomer of a Se-methyl-L-selenocysteine zwitterion.

benefits

Se-methylselenocysteine (MSC) is a naturally occurring selenium compound with favorable pharmacokinetic properties and high peroral bioavailability in humans. MSC has been proven to have a chemo-preventive property, which several authors show via various cell culture models and animal models. It has also been shown to have anti-carcinogenic properties by inducing cell cycle arrest and apoptotic cell death. It is considered a pro-drug because the compound per se is not toxic unless it is metabolized by the enzymes Kynurenine aminotransferase 1 (KYAT1), Kynurenine aminotransferase 3 (KYAT3) and cystathionine γ-lyase (CTH). Of these, KYAT1 plays a vital role in MSC metabolism. KYAT1 is a PLP dependent enzyme whose main function is to cleave carbon-sulfur bonds. KYAT is a bi-functional enzyme that catalyzes transamination and β-elimination reactions with single substrates. KYAT1 metabolizes MSC into β-methylselenopyruvate (MSP) and methylselenol via transamination and β-elimination catalysis.

Se-Methylselenocysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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Se-Methylselenocysteine Suppliers

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View Lastest Price from Se-Methylselenocysteine manufacturers

Shangdong Yuanlitai Nutratech Co.,ltd
Product
L-Se-methylselenocysteine, MSC 26046-90-2
Price
US $0.00-0.00/G
Min. Order
1G
Purity
99%
Supply Ability
1000
Release date
2024-12-04
BINBO BIOLOGICAL CO.,LTD
Product
3-(Methylseleno)-L-alanine 26046-90-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000 kg
Release date
2024-04-07
Hebei Yanxi Chemical Co., Ltd.
Product
(2R)-2-amino-3-methylselanylpropanoic acid 26046-90-2
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-18

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  • Peptide Synthesis
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