ISOXAZOLE-5-CARBONYL CHLORIDE Property

Boiling point:

167-168 °C(lit.)

Density 

1.362 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4980(lit.)

Flash point:

190 °F

storage temp. 

Inert atmosphere,Room Temperature

pka

-4.58±0.50(Predicted)

form 

liquid

color 

Brown

Sensitive 

Moisture Sensitive

BRN 

4375023

CAS DataBase Reference

62348-13-4(CAS DataBase Reference)

Safety

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

Hazard Note 

Harmful/Corrosive/Moisture Sensitive

HazardClass 

8

PackingGroup 

II

HS Code 

2934999090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

ISOXAZOLE-5-CARBONYL CHLORIDE Chemical Properties,Usage,Production

Uses

Isoxazole-5-carbonyl chloride can undergo reaction with 1-benzhydrylpiperazine to give the corresponding 1-benzhydrylpiperazine derivative, which may be used in the treatment of cancer. It can also be used in the synthesis of N-Isoxazole-5-carbonyl-1,3-diphenyl-5-amino-1H-pyrazole, which can act like potent agent in the treatment of neurological and psychiatric illness.