3-(1,3-OXAZOL-5-YL)ANILINE

Product Name: 3-(1,3-OXAZOL-5-YL)ANILINE
CAS No.: 157837-31-5
Chemical Name: 3-(1,3-OXAZOL-5-YL)ANILINE
Synonyms: BUTTPARK 43\57-51;3-(5-Oxazolyl)aniline;3-(Oxazol-5-yl)aniline;4-(3-Aminophenyl)oxazole;5-(3-AMINOPHENYL)OXAZOLE;3-(5-Oxazolyl)benzenamine;3-(oxazol-5-yl)benzenaMine;3-(1,3-OXAZOL-5-YL)ANILINE;Benzenamine, 3-(5-oxazolyl)-;[3-(Oxazol-5-yl)phenyl]amine
CBNumber: CB8266655
Molecular Formula: C9H8N2O
Formula Weight: 160.17
MOL File: 157837-31-5.mol

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3-(1,3-OXAZOL-5-YL)ANILINE Property

Melting point:: 93-95°C
Boiling point:: 359.1±25.0 °C(Predicted)
Density: 1.204
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.81±0.10(Predicted)
form: solid
Appearance: Light brown to brown Solid

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-36-22
Safety Statements: 26-36/37/39
HazardClass: IRRITANT
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: E588755
Product name: 3-(1,3-Oxazol-5-yl)aniline
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 042827
Product name: 3-(1,3-Oxazol-5-yl)aniline
Purity: >95%
Packaging: 500mg
Price: $25
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-V5
Product name: 3-(1,3-Oxazol-5-yl)aniline
Packaging: 250mg
Price: $36
Updated: 2021/12/16

Matrix Scientific

Product number: 042827
Product name: 3-(1,3-Oxazol-5-yl)aniline
Purity: >95%
Packaging: 1g
Price: $39
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-V5
Product name: 3-(1,3-Oxazol-5-yl)aniline
Packaging: 1g
Price: $88
Updated: 2021/12/16

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3-(1,3-OXAZOL-5-YL)ANILINE Chemical Properties,Usage,Production

Synthesis

89808-77-5

157837-31-5

General procedure for the synthesis of 3-(5-oxazolyl)aniline using 5-(3-nitrophenyl)oxazole as starting material: firstly, intermediate 1a (3.52 g, 18.5 mmol) was dissolved in anhydrous ethanol (210 ml), followed by addition of water (21 ml) for dilution. Next, SnCl2-2H2O (20.9 g, 92.6 mmol) and HCl (15 ml, 180 mmol) were added to the reaction system. After the reaction mixture was stirred overnight at room temperature, the pH was adjusted using 10% NaOH aqueous solution to 7. Subsequently, the reaction mixture was extracted several times with EtOAc. The organic phases were combined, dried with MgSO4, filtered and the solvent was evaporated to give 3-(5-oxazolyl)aniline in the form of a light orange powder (2.74 g, 93% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) with chemical shifts of δ8.37 (s, 1H), 7.49 (s, 1H), 7.10 (t, J=7.8 Hz, 1H), 6.90 (t, J=1.8 Hz, 1H), 6.86 (d, J=7.6 Hz, 1H), 6.59-6.54 ( m, 1H), 5.25 (s, 2H).

References

[1] Patent: WO2015/144614, 2015, A1. Location in patent: Page/Page column 32; 33
[2] Patent: EP3144307, 2017, A1. Location in patent: Paragraph 0085; 0087
[3] Patent: WO2007/60026, 2007, A1. Location in patent: Page/Page column 53-54
[4] Patent: EP1612204, 2006, A1. Location in patent: Page/Page column 22

3-(1,3-OXAZOL-5-YL)ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(1,3-OXAZOL-5-YL)ANILINE manufacturers

Career Henan Chemical Co

Product: 3-(1,3-OXAZOL-5-YL)ANILINE 157837-31-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-25

157837-31-5, 3-(1,3-OXAZOL-5-YL)ANILINERelated Search:

3-(1,3-OXAZOL-5-YL)ANILINE 2-(1,3-OXAZOL-5-YL)ANILINE 4-(1,3-OXAZOL-5-YL)ANILINE,4-(1,3-Oxazol-5-yl)aniline, tech 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE 5-(3-Nitrophenyl)oxazole-4-carboxylic acid Ethyl 5-(3-nitrophenyl)oxazole-4-carboxylate 4-(2-CYCLOPROPYL-1,3-OXAZOL-5-YL)ANILINE 4-(2-METHYL-1,3-OXAZOL-5-YL)ANILINE 5-(3-NITROPHENYL)-1,3-OXAZOLE 4-(BENZO[D]OXAZOL-2-YL)ANILINE 4-(4,5-DIHYDRO-1,3-OXAZOL-2-YL)ANILINE 3-(1,2-oxazol-5-yl)aniline 4-(2-METHYL-1,3-OXAZOL-4-YL)ANILINE 4-(1,2-oxazol-5-yl)aniline 3-(4,5-dimethyl-1,3-oxazol-2-yl)aniline 4-(2-methyl-5-phenyl-1,3-oxazol-4-yl)aniline 5-(3-NITRO-PHENYL)-OXAZOL-2-YLAMINE

5-(3-AMINOPHENYL)OXAZOLE

3-(1,3-OXAZOL-5-YL)ANILINE

BUTTPARK 43\57-51

3-(oxazol-5-yl)benzenaMine

3-(5-Oxazolyl)aniline

[3-(1,3-Oxazol-5-yl)phenyl]amine

[3-(Oxazol-5-yl)phenyl]amine

3-(5-Oxazolyl)benzenamine

3-(Oxazol-5-yl)aniline

4-(3-Aminophenyl)oxazole

Benzenamine, 3-(5-oxazolyl)-

157837-31-5

Amines

Phenyls & Phenyl-Het

API intermediates

Phenyls & Phenyl-Het

Amines and Anilines

Heterocycles