3-(1,3-OXAZOL-5-YL)ANILINE
- Product Name
- 3-(1,3-OXAZOL-5-YL)ANILINE
- CAS No.
- 157837-31-5
- Chemical Name
- 3-(1,3-OXAZOL-5-YL)ANILINE
- Synonyms
- BUTTPARK 43\57-51;3-(5-Oxazolyl)aniline;3-(Oxazol-5-yl)aniline;4-(3-Aminophenyl)oxazole;5-(3-AMINOPHENYL)OXAZOLE;3-(5-Oxazolyl)benzenamine;3-(oxazol-5-yl)benzenaMine;3-(1,3-OXAZOL-5-YL)ANILINE;Benzenamine, 3-(5-oxazolyl)-;[3-(Oxazol-5-yl)phenyl]amine
- CBNumber
- CB8266655
- Molecular Formula
- C9H8N2O
- Formula Weight
- 160.17
- MOL File
- 157837-31-5.mol
3-(1,3-OXAZOL-5-YL)ANILINE Property
- Melting point:
- 93-95°C
- Boiling point:
- 359.1±25.0 °C(Predicted)
- Density
- 1.204
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.81±0.10(Predicted)
- form
- solid
- Appearance
- Light brown to brown Solid
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-36-22
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2921420090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E588755
- Product name
- 3-(1,3-Oxazol-5-yl)aniline
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 042827
- Product name
- 3-(1,3-Oxazol-5-yl)aniline
- Purity
- >95%
- Packaging
- 500mg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 4H30-1-V5
- Product name
- 3-(1,3-Oxazol-5-yl)aniline
- Packaging
- 250mg
- Price
- $36
- Updated
- 2021/12/16
- Product number
- 042827
- Product name
- 3-(1,3-Oxazol-5-yl)aniline
- Purity
- >95%
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- 4H30-1-V5
- Product name
- 3-(1,3-Oxazol-5-yl)aniline
- Packaging
- 1g
- Price
- $88
- Updated
- 2021/12/16
3-(1,3-OXAZOL-5-YL)ANILINE Chemical Properties,Usage,Production
Synthesis
89808-77-5
157837-31-5
General procedure for the synthesis of 3-(5-oxazolyl)aniline using 5-(3-nitrophenyl)oxazole as starting material: firstly, intermediate 1a (3.52 g, 18.5 mmol) was dissolved in anhydrous ethanol (210 ml), followed by addition of water (21 ml) for dilution. Next, SnCl2-2H2O (20.9 g, 92.6 mmol) and HCl (15 ml, 180 mmol) were added to the reaction system. After the reaction mixture was stirred overnight at room temperature, the pH was adjusted using 10% NaOH aqueous solution to 7. Subsequently, the reaction mixture was extracted several times with EtOAc. The organic phases were combined, dried with MgSO4, filtered and the solvent was evaporated to give 3-(5-oxazolyl)aniline in the form of a light orange powder (2.74 g, 93% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) with chemical shifts of δ8.37 (s, 1H), 7.49 (s, 1H), 7.10 (t, J=7.8 Hz, 1H), 6.90 (t, J=1.8 Hz, 1H), 6.86 (d, J=7.6 Hz, 1H), 6.59-6.54 ( m, 1H), 5.25 (s, 2H).
References
[1] Patent: WO2015/144614, 2015, A1. Location in patent: Page/Page column 32; 33
[2] Patent: EP3144307, 2017, A1. Location in patent: Paragraph 0085; 0087
[3] Patent: WO2007/60026, 2007, A1. Location in patent: Page/Page column 53-54
[4] Patent: EP1612204, 2006, A1. Location in patent: Page/Page column 22
3-(1,3-OXAZOL-5-YL)ANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
3-(1,3-OXAZOL-5-YL)ANILINE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 3-(1,3-OXAZOL-5-YL)ANILINE manufacturers
- Product
- 3-(1,3-OXAZOL-5-YL)ANILINE 157837-31-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25