ChemicalBook > CAS DataBase List > (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid

(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid

Product Name
(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid
CAS No.
1378388-16-9
Chemical Name
(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid
Synonyms
GS-5816 interMediate;Velpatasvir Impurity 5;Velpatasvir Intermediate 3;Velpatasvir Intermediate-I SS-Isomer;Velpatasvir intermediate II- SS isomer;(2S,4S)-4-(Methoxymethyl)-1,2-pyrrolidine;(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl);N-Tert-Butoxycarbonyl-(4S)-4-Methoxymethyl-L-proline;(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline;(2s,4s)-4-(methoxymethyl)-1,2-pyrrolidinedicarboxylic acid
CBNumber
CB82671053
Molecular Formula
C12H21NO5
Formula Weight
259.3
MOL File
1378388-16-9.mol
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(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid Property

Boiling point:
371.2±27.0 °C(Predicted)
Density 
1.162±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.91±0.40(Predicted)
form 
Solid
color 
White to off-white
optical activity
Consistent with structure
Water Solubility 
12.2g/L
InChI
InChI=1S/C12H21NO5/c1-12(2,3)18-11(16)13-6-8(7-17-4)5-9(13)10(14)15/h8-9H,5-7H2,1-4H3,(H,14,15)/t8-,9-/m0/s1
InChIKey
OHPUCEUCBHBIAW-IUCAKERBSA-N
SMILES
N1(C(OC(C)(C)C)=O)C[C@@H](COC)C[C@H]1C(O)=O
LogP
1.16
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B809148
Product name
(2S,4S)-1-(tert-Butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylicAcid
Packaging
5g
Price
$585
Updated
2021/12/16
TRC
Product number
B809148
Product name
(2S,4S)-1-(tert-Butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylicAcid
Packaging
10g
Price
$1025
Updated
2021/12/16
AK Scientific
Product number
0455DU
Product name
(2S,4S)-1-(Tert-butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylicacid
Packaging
10g
Price
$479
Updated
2021/12/16
Ambeed
Product number
A143736
Product name
(2S,4S)-1-(tert-Butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylicacid
Purity
95%
Packaging
250mg
Price
$26
Updated
2021/12/16
Ambeed
Product number
A143736
Product name
(2S,4S)-1-(tert-Butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylicacid
Purity
95%
Packaging
1g
Price
$60
Updated
2021/12/16
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(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

(2S,4S)-1-(tert-Butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylic Acid is an antiviral agent and Velpatasvir (V116000) intermediate. Velpatasvir is a NS5A inhibitor in patients with hepatitis C (HCV) infection.

(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid Suppliers

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View Lastest Price from (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid 1378388-16-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Guangzhou Sunton Biotechnology Co., Ltd.
Product
(2S,4S)-4-(methoxymethyl)-1, 2-pyrrolidine dicarboxylic acid, 1-tert-butyl ester 1378388-16-9
Price
US $48.00-40.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200tons
Release date
2021-03-30
Zhuozhou Wenxi import and Export Co., Ltd
Product
(2S,4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)pyrrolidine-2-carboxylic acid 1378388-16-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

1378388-16-9, (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acidRelated Search:

tert-Butyl carbazate (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid Cyclopropanamine,2-(3,4-difluorophenyl)-(1R,2S) -(2R,3R)-2,3-dihydroxybutanedioate (1:1) 9-Bromo-3-(2-Bromo Acetyl)-10,11-Dihydro-5H-dibenzo(c,g) Chromen-8(9H)-one N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER Velpatasvir intermediate Velpatasvir Velpatasvir intermediate Velpatasvir intermediate (R)-2-(methoxycarbonylamino)-2-phenylacetic acid Velpatasvir Co Povidone Velpatasvir intermediate (2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidine-2-carboxylic acid BOC-L-PYROGLUTAMIC ACID BENZYL ESTER Velpatasvir-A12 3-(2-bromoacetyl)-10,11-dihydro-5H-Benzo[d]naphtho[2,3-b]pyran-8(9H)-one (2S,4R)-4-(Methoxymethyl)-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid

  • Velpatasvir Impurity 5
  • (2S,4S)-4-(Methoxymethyl)-1,2-pyrrolidine
  • (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid
  • (2S,4S)-4-(Methoxymethyl)-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
  • GS-5816 interMediate
  • 3-(2-bromoacetyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one
  • Velpatasvir Intermediate 3
  • N-Tert-Butoxycarbonyl-(4S)-4-Methoxymethyl-L-proline
  • (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)
  • (2s,4s)-4-(methoxymethyl)-1,2-pyrrolidinedicarboxylic acid
  • (2 S,4S)-4-(methoxy methyl)-1,2-pyrrolidine dimethyl acid 1-tert-butyl ester
  • 1,2-Pyrrolidinedicarboxylic acid, 4-(methoxymethyl)-, 1-(1,1-dimethylethyl) ester, (2S,4S)-
  • (2S,4S)-4-(methoxymethyl)-1, 2-pyrrolidine dicarboxylic acid, 1-tert-butyl ester
  • Velpatasvir Intermediate-I SS-Isomer
  • (2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine...
  • Velpatasvir intermediate II- SS isomer
  • (2S, 4S) -1- (tert butoxycarbonyl) -4- (methoxymethyl) pyrroline-2-carboxylic acid
  • (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline
  • 1378388-16-9
  • 378390-29-4
  • 1378388-16-9