ChemicalBook > CAS DataBase List > 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)

Product Name
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
CAS No.
33985-68-1
Chemical Name
3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
Synonyms
C-DIM5;DIM-C-pPhOMe;DIM C pPhOMe;DIM-C-pPhOCH3;C-DIM5 ，S0149;DIM-C-pPhOCH3(C-DIM5);DIM-C-pPhOCH3 >=98% (HPLC);DIM-C-pPhOCH3, 10 mM in DMSO;Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane;1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane
CBNumber
CB82682260
Molecular Formula
C24H20N2O
Formula Weight
352.43
MOL File
33985-68-1.mol
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3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Property

Melting point:
187-189 °C
Boiling point:
592.7±50.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: ≥30mg/mL
form 
powder
pka
16.63±0.30(Predicted)
color 
off-white to light yellow
InChI
1S/C24H20N2O/c1-27-17-12-10-16(11-13-17)24(20-14-25-22-8-4-2-6-18(20)22)21-15-26-23-9-5-3-7-19(21)23/h2-15,24-26H,1H3
InChIKey
ZCCMKJAXOIFTHH-UHFFFAOYSA-N
SMILES
COc1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45
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Safety

WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7946
Product name
DIM-C-pPhOCH3
Purity
≥98% (HPLC)
Packaging
5mg
Price
$125
Updated
2026/03/19
Sigma-Aldrich
Product number
D7946
Product name
DIM-C-pPhOCH3
Purity
≥98% (HPLC)
Packaging
25mg
Price
$510
Updated
2026/03/19
Cayman Chemical
Product number
27980
Product name
C-DIM5
Packaging
5mg
Price
$105
Updated
2024/03/01
Cayman Chemical
Product number
27980
Product name
C-DIM5
Packaging
25mg
Price
$420
Updated
2024/03/01
Cayman Chemical
Product number
27980
Product name
C-DIM5
Packaging
1mg
Price
$32
Updated
2024/03/01
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3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Chemical Properties,Usage,Production

Uses

[Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane, is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.

Biological Activity

DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist

in vivo

DIM-C-pPhOCH3 (25 mg/kg/d) also inhibits tumor growth in athymic nude mice bearing RKO cell xenografts. The effects of DIM-C-pPhOCH3 (25 mg/kg/d) on colon tumor growth are also investigated in athymic nude mice bearing RKO cell xenografts. Treatment with the DIM-C-pPhOCH3 significantly decreases tumor volumes and final tumor weights compared with corn oil controls[1].

IC 50

Nur77/NR4A1

storage

Store at -20°C

3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole) Suppliers

China 53 United Kingdom 1 United States 6 Global 60
Shanghai Run-Biotech Co., Ltd.
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021-57171705 13817537615
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China
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2280
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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+86-21-61629029
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product02@bidepharm.com
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China
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39999
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Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
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China
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4827
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55
Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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China
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9803
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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China
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86249
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ShangHai Biochempartner Co.,Ltd
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Shanghai SuperLan Chemcial Technique Centre
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Rhawn Reagent
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Angel Pharmatech, Ltd.
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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
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chemflowtech@sina.com
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33985-68-1, 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)Related Search:

2-Phenylindole

  • DIM-C-pPhOCH3
  • C-DIM5
  • 3,3'-((4-Methoxyphenyl)Methylene)bis(1H-indole)
  • 1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane
  • DIM-C-pPhOCH3(C-DIM5)
  • 1H-Indole, 3,3'-[(4-methoxyphenyl)methylene]bis-
  • DIM-C-pPhOCH3 >=98% (HPLC)
  • Bis(1H-indol-3-yl)(4-methoxyphenyl)]methane
  • Inhibitor,DIM-C-pPhOCH-3,DIM C pPhOCH3,DIMCpPhOCH3,inhibit
  • DIM C pPhOMe
  • DIM-C-pPhOMe
  • DIM-C-pPhOCH3, 10 mM in DMSO
  • C-DIM5 ，S0149
  • 33985-68-1