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CGP 71683 HYDROCHLORIDE

Product Name
CGP 71683 HYDROCHLORIDE
CAS No.
192322-50-2
Chemical Name
CGP 71683 HYDROCHLORIDE
Synonyms
CGP 71683;CGP71683HCl;CGP-71683A HCl;UNII-45B73P82A3;CGP 71683 HYDROCHLORIDE;CGP 71683A hydrochloride;CGP-71683A; CGP 71683A; CGP71683A; UNII-45B73P82A3;N-[[TRANS-4-[[(4-AMINO-2-QUINAZOLINYL)AMINO]METHYL]CYCLOHEXYL]METHYL]-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-rel-(((1r,4r)-4-(((4-Aminoquinazolin-2-yl)amino)methyl)cyclohexyl)methyl)naphthalene-1-sulfonamide hydrochloride;1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
CBNumber
CB8269070
Molecular Formula
C26H30ClN5O2S
Formula Weight
512.07
MOL File
192322-50-2.mol
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CGP 71683 HYDROCHLORIDE Property

storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: ~14 mg/mL, soluble
form 
solid
color 
off-white
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Safety

Safety Statements 
24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28778
Product name
CGP 71683 (hydrochloride)
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
28778
Product name
CGP 71683 (hydrochloride)
Packaging
10mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
28778
Product name
CGP 71683 (hydrochloride)
Packaging
5mg
Price
$145
Updated
2024/03/01
Tocris
Product number
2199
Product name
CGP71683hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$223
Updated
2021/12/16
Tocris
Product number
2199
Product name
CGP71683hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$934
Updated
2021/12/16
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CGP 71683 HYDROCHLORIDE Chemical Properties,Usage,Production

Description

CGP 71683 is an antagonist of neuropeptide Y (NPY) receptor Y5 (IC50 = 1.4 nM in a radioligand binding assay). It is selective for Y5 over Y1, Y2, and Y4 receptors (IC50s = 2,765, 7,187, and 5,637 nM, respectively). It inhibits NPY-induced increases in BT-549 cell growth and MDA-MB-231 cell migration when used at a concentration of 0.25 μM. CGP 71683 (10 mg/kg, i.p.) inhibits increases in food intake induced by intracerebroventricular administration of NPY in rats.

Biological Activity

Extremely selective, non-peptide NPY Y 5 receptor antagonist. Displays > 1000-fold selectivity over Y 1 , Y 2 and Y 4 receptors; IC 50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y 5 , Y 1 , Y 2 and Y 4 receptors respectively. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats.

storage

Store at +4°C

CGP 71683 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CGP 71683 HYDROCHLORIDE Suppliers

China 41 Europe 1 Germany 3 India 1 Switzerland 1 United Kingdom 2 United States 8 Global 57
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
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55
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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Guangzhou Zhiya Chemdrugs Co.,Ltd
Tel
18122150900
Fax
QQ:2869377561
Email
sculk28@163.com
Country
China
ProdList
646
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2989
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58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9747
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58
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15820
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58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Country
China
ProdList
1988
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58

192322-50-2, CGP 71683 HYDROCHLORIDERelated Search:

CGP 71683 HYDROCHLORIDE W-5 HYDROCHLORIDE

  • CGP 71683 HYDROCHLORIDE
  • N-[[TRANS-4-[[(4-AMINO-2-QUINAZOLINYL)AMINO]METHYL]CYCLOHEXYL]METHYL]-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
  • CGP 71683
  • CGP71683HCl
  • 1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
  • UNII-45B73P82A3
  • CGP-71683A; CGP 71683A; CGP71683A; UNII-45B73P82A3
  • CGP 71683A hydrochloride
  • CGP-71683A HCl
  • N-rel-(((1r,4r)-4-(((4-Aminoquinazolin-2-yl)amino)methyl)cyclohexyl)methyl)naphthalene-1-sulfonamide hydrochloride
  • NPY receptor,CGP-71683,CGP 71683,Inhibitor,inhibit,CGP71683 hydrochloride,CGP-71683 hydrochloride,CGP71683,Neuropeptide Y Receptor
  • 192322-50-2
  • C26H30ClN5O2S
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Forensic and Veterinary Standards
  • Chromatography
  • Drug Standards
  • Neuropeptide Y (NPY ) receptor