Z-VDVAD-AFC

Product Name: Z-VDVAD-AFC
CAS No.: 219138-08-6
Chemical Name: Z-VDVAD-AFC
Synonyms: Z-VDVAD-AFC;CBZ-VDVAD-AFC;Z-VDVAD-AFC USP/EP/BP;Z-Val-Asp-Ala-Asp-AFC;Z-VAL-ASP-VAL-ALA-ASP-AFC;CASPASE-2 SUBSTRATE I, FLUOROGENIC;L-α-Asparagine,N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-;L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine;(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid
CBNumber: CB8269964
Molecular Formula: C39H45F3N6O13
Formula Weight: 862.8
MOL File: 219138-08-6.mol

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Z-VDVAD-AFC Property

Boiling point:: 1153.6±65.0 °C(Predicted)
Density: 1.399±0.06 g/cm3(Predicted)
storage temp.: -15°C
pka: 4.09±0.10(Predicted)
Sequence: {Z}-Val-Asp-Val-Ala-Asp-{AFC}

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: HCH0136645
Product name: CASPASE-2 SUBSTRATE I, FLUOROGENIC
Purity: 95.00%
Packaging: 5MG
Price: $499.66
Updated: 2021/12/16

Chem-Impex

Product number: 32763
Product name: Z-Val-Asp-Val-Ala-Asp-AFC
Packaging: 5MG
Price: $805
Updated: 2021/12/16

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Z-VDVAD-AFC Chemical Properties,Usage,Production

Uses

Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

References

[1] Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79. DOI:10.1016/j.freeradbiomed.2010.11.022

Z-VDVAD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Z-VDVAD-AFC manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Z-VDVAD-AFC 219138-08-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-25

Career Henan Chemical Co

Product: Z-VDVAD-AFC 219138-08-6
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-01-08

219138-08-6, Z-VDVAD-AFCRelated Search:

Z-VAL-PHE-OME Z-VAL-VAL-ARG-AMC Z-VAL-ALA-ASN-AMC Z-YVAD-AFC Z-VEID-AFC Z-TYR-SER-OH UROKINASE SUBSTRATE I, COLORIMETRIC Z-VAL-ALA-ASP-AMC BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE Z-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE Z-VAL-LYS-LYS-ARG-AFC Z-VRPR-FMK (trifluoroacetate salt) L-Alaninamide,N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-[(2,6-dichlorobenzoyl)oxy]-1-(2-ethoxy-2-oxoethyl)-2-oxopropyl]-(9CI) AC-VDVAD-AFC SUC-ALA-ALA-ALA-AMC Z-VDVAD-AFC AFC Caspase 2, Fluorometric Substrate, VDVAD-AFC

CASPASE-2 SUBSTRATE I, FLUOROGENIC

Z-VDVAD-AFC

Z-VAL-ASP-VAL-ALA-ASP-AFC

Z-Val-Asp-Ala-Asp-AFC

(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid

N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine

L-α-Asparagine,N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-

Z-VDVAD-AFC USP/EP/BP

CBZ-VDVAD-AFC

L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)

219138-08-6

C39H45F3N6O13