LCZ696 InteMediate
- Product Name
- LCZ696 InteMediate
- CAS No.
- 1426129-50-1
- Chemical Name
- LCZ696 InteMediate
- Synonyms
- (R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate;150kg;EOS-61581;LCZ696interN-3;Shakubiqu 50-1;LCZ696 InteMediate;(1-([1,1'-biphenyL;LCZ696 InteMediate I;(R)-tert-butyl (1-([1;)-3-hydroxypropan-2-yL
- CBNumber
- CB82723677
- Molecular Formula
- C20H25NO3
- Formula Weight
- 327.42
- MOL File
- 1426129-50-1.mol
LCZ696 InteMediate Property
- Boiling point:
- 514.5±50.0 °C(Predicted)
- Density
- 1.103±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 11.85±0.46(Predicted)
- InChI
- InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1
- InChIKey
- TYQICOFAZDVKMK-GOSISDBHSA-N
- SMILES
- C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B397950
- Product name
- N-[(1R)-2-[1,1''-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-carbamicAcid1,1-DimethylethylEster
- Packaging
- 10g
- Price
- $880
- Updated
- 2021/12/16
- Product number
- X3805
- Product name
- (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
- Packaging
- 25g
- Price
- $967
- Updated
- 2021/12/16
- Product number
- J56908
- Product name
- (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
- Packaging
- 25g
- Price
- $725
- Updated
- 2021/12/16
- Product number
- A120802
- Product name
- (R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $5
- Updated
- 2021/12/16
- Product number
- A120802
- Product name
- (R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
- Purity
- 95%
- Packaging
- 1g
- Price
- $7
- Updated
- 2021/12/16
LCZ696 InteMediate Chemical Properties,Usage,Production
Description
LCZ696 InteMediate is chemically known as (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate. It is a pharmaceutical intermediate compound and a by-product in the preparation of LCZ696 (Sacubitril/valsartan). LCZ696 InteMediate can also be used to synthesize (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid.
Uses
N-?[(1R)?-?2-?[1,?1''-?Biphenyl]?-?4-?yl-?1-?(hydroxymethyl)?ethyl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).
LCZ696 InteMediate Preparation Products And Raw materials
Raw materials
Preparation Products
LCZ696 InteMediate Suppliers
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- 0512-62857507
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- +86-512-62857507
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- Country
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View Lastest Price from LCZ696 InteMediate manufacturers
- Product
- LCZ696 InteMediate 1426129-50-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-06
- Product
- LCZ696 InteMediate 1426129-50-1
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-11
- Product
- LCZ696 InteMediate 1426129-50-1
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-08-08