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LCZ696 InteMediate

Product Name
LCZ696 InteMediate
CAS No.
1426129-50-1
Chemical Name
LCZ696 InteMediate
Synonyms
(R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate;150kg;EOS-61581;LCZ696interN-3;Shakubiqu 50-1;LCZ696 InteMediate;(1-([1,1'-biphenyL;LCZ696 InteMediate I;(R)-tert-butyl (1-([1;)-3-hydroxypropan-2-yL
CBNumber
CB82723677
Molecular Formula
C20H25NO3
Formula Weight
327.42
MOL File
1426129-50-1.mol
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LCZ696 InteMediate Property

Boiling point:
514.5±50.0 °C(Predicted)
Density 
1.103±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.85±0.46(Predicted)
InChI
InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1
InChIKey
TYQICOFAZDVKMK-GOSISDBHSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B397950
Product name
N-​[(1R)​-​2-​[1,​1''-​Biphenyl]​-​4-​yl-​1-​(hydroxymethyl)​ethyl]​-carbamicAcid1,​1-​DimethylethylEster
Packaging
10g
Price
$880
Updated
2021/12/16
AK Scientific
Product number
J56908
Product name
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Packaging
25g
Price
$725
Updated
2021/12/16
AK Scientific
Product number
X3805
Product name
(R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Packaging
25g
Price
$967
Updated
2021/12/16
Ambeed
Product number
A120802
Product name
(R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Purity
95%
Packaging
250mg
Price
$5
Updated
2021/12/16
Ambeed
Product number
A120802
Product name
(R)-tert-Butyl(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
Purity
95%
Packaging
1g
Price
$7
Updated
2021/12/16
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LCZ696 InteMediate Chemical Properties,Usage,Production

Description

LCZ696 InteMediate is chemically known as (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate. It is a pharmaceutical intermediate compound and a by-product in the preparation of LCZ696 (Sacubitril/valsartan). LCZ696 InteMediate can also be used to synthesize (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid.

Uses

N-?[(1R)?-?2-?[1,?1''-?Biphenyl]?-?4-?yl-?1-?(hydroxymethyl)?ethyl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).

LCZ696 InteMediate Preparation Products And Raw materials

Raw materials

Preparation Products

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LCZ696 InteMediate Suppliers

China 277 India 5 United States 6 Global 288
Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
965
Advantage
58
hongqing Huafeng Pharmaceutical Technology Co., LTD
Tel
023-67950001 13883380852
Fax
023-68265899
Email
cqhfyy@foxmail.com
Country
China
ProdList
35
Advantage
55
Shandong Sihuan Pharmaceutical Co., Ltd.
Tel
0531-88993893 13335127975
Fax
QQ:787658403
Email
fairouz@sdsihuanpharm.com
Country
China
ProdList
88
Advantage
58
Shanghai Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
021-58955996
Email
info@chemexpress.com
Country
China
ProdList
774
Advantage
58
Shaanxi Youbang Biomedical Technology Co., Ltd.
Tel
0913-7167565 18754046789
Email
316745545@qq.com
Country
China
ProdList
212
Advantage
58
CHONGOINGJICHENG BIOPHARMACEUTICAL SCIENCE AND TECHNOLOGY CO.. LTD
Tel
023-67646862 18983213987
Email
cqlcg@foxmail.com
Country
China
ProdList
11
Advantage
58
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
995
Advantage
64
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View Lastest Price from LCZ696 InteMediate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
LCZ696 InteMediate 1426129-50-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-06
Shaanxi Dideu Medichem Co. Ltd
Product
LCZ696 InteMediate 1426129-50-1
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-11
Henan Bao Enluo International TradeCo.，LTD
Product
LCZ696 InteMediate 1426129-50-1
Price
US $50.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-08-08

1426129-50-1, LCZ696 InteMediateRelated Search:

Sacubitril Impurity 10 LCZ696 LCZ Impurity (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one Sacubitril Impurity 72 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid (S)-5-[(Biphenyl-4-yl)carbonyl]pyrrolidin-2-one LCZ696 interMediate Valsartan (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate AHU-377 (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
  • LCZ696 InteMediate
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate
  • LCZ696(valsartan + sacubitril) impurity 29
  • (R) -tert-butyl (1-([1,1'-biphenyl] -4-yl) -3-hydroxypropane-2-yl) carbamate
  • (R)-tert-butyl (1-([1
  • 1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • 1)(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • LCZ-696 Intermediate 39
  • EOS-61581
  • Carbamic acid, N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxyethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
  • (2-Biphenyl-4-yl-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester
  • LCZ696interN-3
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate1426129-50-1
  • (1-([1,1'-biphenyL
  • )-3-hydroxypropan-2-yL
  • tert-butylN-[(2R)-1-hydroxy-3-(4-phenylphenyl)propan-2-yl]carbamate
  • LCZ696 InteMediate USP/EP/BP
  • (R)-tert-butyl 1-(biphenyl-4-yl)-3-hydroxypropan-2-ylcarbamate
  • N-[(1R)-2-[1,1’-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-y...
  • D-N-Boc-biphenyl propanol
  • (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamateQ: What is (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the CAS Number of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What is the storage condition of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate Q: What are the applications of (R)-tert-butyl(1-([1,1-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxy
  • Benzenamine,2-bromo-10-methyl-
  • Methanol,3-chloro-,benzoate
  • 1,4-Benzenedicarboxylicacid,bis(4-methylethyl)ester
  • low price LCZ696 Intermediate
  • 1,1-Dimethylethyl N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamate
  • AMINO DIPHENYL METHANOL
  • Sacubitril Impurity 78
  • tert-Butyl N-(1R)-2-biphenyl-4-yl-1-(hydroxymethyl)ethylcarbamate
  • 150kg
  • (R)-2-(Boc-amino)-3-(4-biphenylyl)-1-propanol
  • LCZ696 InteMediate I
  • Shakubiqu 50-1
  • LCZ696 Intermediate A-1
  • Calcium bis(4-{[(2S,4R)-1-(4-biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoate)
  • (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate
  • N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester
  • 1426129-50-1
  • LCZ696
  • LCZ 696
  • 1426129-50-1